De Soto County, county in Mississippi, United States. As of 2020 county had an estimated population of 173,323 inhabitants. The county was created 187 years ago in 1836. Its county seat is "Hernando".
There are 5 city/town in De Soto County, MS. The largest city of De Soto County is Southaven with a population of 56,644. Other cities include, Olive Branch population 39,646, Horn Lake population 27,282, Hernando population 16,854 and Walls population 1,441
Cities, Towns, Neighborhoods & Other Populated Places in De Soto County.
|Hernando||City in Mississippi||De Soto||16,854|
|Horn Lake||City in De Soto County, Mississippi, United States||De Soto||27,282|
|Olive Branch||City in De Soto County, Mississippi, United States||De Soto||39,646|
|Southaven||City in DeSoto County, Mississippi, United States||De Soto||56,644|
|Walls||Town in Mississippi||De Soto||1,441|