How far is Port Isabel, TX from Amarillo, TX?
The driving distance from Port Isabel, TX to Amarillo, TX is about 798.6 miles (1285.2 km), with a travel time of about 11h 50m by car.
- The straight-line flight distance is about 689 miles (1108.8 km).
- For a round trip, plan for roughly 23h 40m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 11h 50m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Areas Of Fog
Driving Route Map
The map below follows the saved road route between Port Isabel and Amarillo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Port Isabel and Amarillo.
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1
Start on South Musina Street
985 ft · 33 sec · South Musina Street
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2
Turn left onto West Queen Isabella Boulevard
741 ft · 23 sec · West Queen Isabella Boulevard
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3
Turn straight onto State Highway 100
1 mi · 3 min · State Highway 100
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4
Turn left
14.1 mi · 15 min
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5
Take the exit slight right toward TX 550
936 ft · 23 sec
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6
Keep slight right to continue on TX 550
14 m · 1 sec
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7
Turn right onto State Highway 550
3.6 mi · 4 min · State Highway 550
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8
Continue straight
1.9 mi · 2 min
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9
Continue on I-169, TX 550 Toll
1.5 km · 59 sec · I-169, TX 550 Toll
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10
Continue on Interstate 169
3.6 mi · 4 min · Interstate 169
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11
Merge slight left onto North Expressway
2.2 mi · 2 min · North Expressway
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12
Continue on U.S. Highway 77
102 mi · 1 hr 53 min · U.S. Highway 77
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13
Keep slight right
623 ft · 8 sec
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14
Keep slight right
1.2 km · 2 min
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15
Turn left onto FM 772
1009 ft · 17 sec · FM 772
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16
Turn straight onto South 6th Street
4.4 mi · 7 min · South 6th Street
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17
Turn left onto West King Avenue
14.5 mi · 18 min · West King Avenue
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18
Take the ramp right
1 km · 2 min
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19
Merge slight left
54.2 mi · 1 hr 2 min
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20
Keep slight left to continue on Nueces Street
14.7 mi · 19 min · Nueces Street
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21
Continue straight
1199 ft · 16 sec
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22
Take the exit straight
68.3 mi · 1 hr 11 min
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23
Take the exit slight right toward Cesar Estrada Chavez Boulevard, Alamodome
1054 ft · 28 sec
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24
Turn left onto East César E. Chávez Boulevard
1.4 mi · 3 min · East César E. Chávez Boulevard
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25
Take the ramp straight toward I 10 West, I 35 North
1303 ft · 32 sec
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26
Merge slight left onto South Pan Am Expressway
28 m · 1 sec · South Pan Am Expressway
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27
Take the exit slight right toward I 10 West, US 87 North: El Paso
1.4 km · 1 min · McDermott Freeway
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28
Keep slight left to continue on McDermott Freeway
14.6 mi · 17 min · McDermott Freeway
-
29
Keep slight right
98.7 mi · 1 hr 37 min
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30
Take the exit slight right toward US 83 North, US 377: Junction, Menard
1665 ft · 44 sec
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31
Turn right onto North Main Street
29.3 mi · 31 min · North Main Street
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32
Continue on Frisco Avenue
41.9 mi · 45 min · Frisco Avenue
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33
Continue on Roberts Avenue
16.5 mi · 18 min · Roberts Avenue
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34
Turn right onto Hutchings Avenue
118 m · 18 sec · Hutchings Avenue
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35
Turn left onto North Broadway Street
6.3 mi · 7 min · North Broadway Street
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36
Turn right
12.3 mi · 13 min
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37
Turn left onto State Highway 153
29.5 mi · 33 min · State Highway 153
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38
Keep slight right to continue on State Highway 153
6 m · 1 sec · State Highway 153
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39
Turn right onto State Highway 70
10.4 mi · 11 min · State Highway 70
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40
Continue on Lamar Street
1.3 km · 1 min · Lamar Street
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41
Turn left onto Northwest Georgia Avenue
670 ft · 17 sec · Northwest Georgia Avenue
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42
Take the ramp slight left toward I 20 West: Midland
104 m · 8 sec
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43
Merge slight left
6 mi · 6 min
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44
Take the exit slight right toward US 84 West: Snyder, Lubbock
1721 ft · 20 sec
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45
Keep slight left
74.2 mi · 1 hr 14 min
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46
Turn right onto South Avenue F
1 mi · 2 min · South Avenue F
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47
Keep slight left to continue on North Avenue F
617 ft · 11 sec · North Avenue F
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48
Turn straight onto Ralls Road
1863 ft · 39 sec · Ralls Road
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49
Turn left onto East 15th Street
734 ft · 17 sec · East 15th Street
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50
Turn right onto North US Highway 84
1 mi · 1 min · North US Highway 84
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51
Continue on Highway 84
20 mi · 20 min · Highway 84
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52
Continue on Trooper Jerry Don Davis Memorial Highway
4.6 mi · 5 min · Trooper Jerry Don Davis Memorial Highway
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53
Continue on East Highway 84
6.8 mi · 7 min · East Highway 84
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54
Continue on Slaton Road
4.5 mi · 6 min · Slaton Road
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55
Take the exit slight right
1302 ft · 27 sec
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56
Turn slight right onto Interstate 27
98 m · 6 sec · Interstate 27
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57
Take the ramp straight
1303 ft · 32 sec
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58
Merge slight left onto Marshall Formby Memorial Highway
109.9 mi · 1 hr 51 min · Marshall Formby Memorial Highway
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59
Continue on Canyon Expressway
13.5 mi · 15 min · Canyon Expressway
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60
Keep slight left to continue on US 87 North
1.5 km · 2 min
-
61
Keep slight right to continue on South Fillmore Street
1.1 km · 2 min · South Fillmore Street
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62
Turn right onto East Amarillo Boulevard
32 m · 1 sec · East Amarillo Boulevard
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63
Arrive at your destination
0 m · 1 sec · East Amarillo Boulevard
Car Route Details
A richer read on the saved driving route between Port Isabel and Amarillo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Marshall Formby Memorial Highway
Merge slight left onto Marshall Formby Memorial Highway
110 mi · 01h 51m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving Port Isabel and Areas Of Fog near Amarillo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Port Isabel to Amarillo?
The road trip is about 798.6 miles (1285.2 km) and usually takes 11h 50m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Junction is a useful midpoint, sitting about 398 miles from Port Isabel and 400.6 miles from Amarillo.
How much longer is the road route than the straight-line distance?
The direct path is about 689 miles (1108.8 km), while the road route adds roughly 109.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $108.18 one way or $216.37 round trip. Estimated CO2 is about 250.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Port Isabel and Areas Of Fog near Amarillo.
Flight Path Map
This map shows the direct air route between Port Isabel and Amarillo. Straight-line distance: 689 mi (1108.84 km).
#1 Port Isabel
City in Cameron County, Texas, United States
| Population | 6,226 |
| Coordinates | 26.0734100, -97.2085800 |
| Altitude | 2 |
| Country | United States |
#2 Amarillo
The second most populous city in Texas Panhandle.
| Population | 199,654 |
| Coordinates | 35.2220000, -101.8313000 |
| Altitude | 1118 |
| Country | United States |
End: East Amarillo Boulevard (-101.8313, 35.221963)
Estimated Travel Time
Distance: 1285 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 26h 36m |
| 40 mph (64.37 km/h) | 19h 57m |
| 50 mph (80.47 km/h) | 15h 58m |
| 60 mph (96.56 km/h) | 13h 18m |
| 70 mph (112.65 km/h) | 11h 24m |
| 80 mph (129 km/h) | 09h 57m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.84 | $108.18 | $216.37 |
| Mid-grade | $4.35 | $122.50 | $245.00 |
| Premium | $4.72 | $133.09 | $266.19 |
| Diesel | $5.78 | $162.77 | $325.54 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Oct 15, 2026