How far is Port Isabel, TX from Houston, TX?
The driving distance from Port Isabel, TX to Houston, TX is about 363.8 miles (585.5 km), with a travel time of about 05h 41m by car.
- The straight-line flight distance is about 278.7 miles (448.5 km).
- For a round trip, plan for roughly 11h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 41m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Chance Showers And Thunderstorms then Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Port Isabel and Houston.
Turn-by-Turn Driving Directions
Step-by-step road directions between Port Isabel and Houston.
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1
Start on South Musina Street
985 ft · 33 sec · South Musina Street
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2
Turn left onto West Queen Isabella Boulevard
741 ft · 23 sec · West Queen Isabella Boulevard
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3
Turn straight onto State Highway 100
1 mi · 3 min · State Highway 100
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4
Turn left
14.1 mi · 15 min
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5
Take the exit slight right toward TX 550
936 ft · 23 sec
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6
Keep slight right to continue on TX 550
14 m · 1 sec
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7
Turn right onto State Highway 550
3.6 mi · 4 min · State Highway 550
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8
Continue straight
1.9 mi · 2 min
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9
Continue on I-169, TX 550 Toll
1.5 km · 59 sec · I-169, TX 550 Toll
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10
Continue on Interstate 169
3.6 mi · 4 min · Interstate 169
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11
Merge slight left onto North Expressway
2.2 mi · 2 min · North Expressway
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12
Continue on U.S. Highway 77
102 mi · 1 hr 53 min · U.S. Highway 77
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13
Keep slight left
1157 ft · 14 sec
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14
Merge slight right
1.2 mi · 1 min
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15
Continue on U.S. Highway 77
11.6 mi · 13 min · U.S. Highway 77
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16
Take the exit slight right
1410 ft · 34 sec
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17
Turn straight onto US Highway 77 Frontage Road
148 m · 18 sec · US Highway 77 Frontage Road
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18
Turn right onto County Road 10
1 mi · 4 min · County Road 10
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19
Turn left onto County Road 79
4 mi · 16 min · County Road 79
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20
Turn left onto County Road 18
848 ft · 44 sec · County Road 18
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21
Turn sharp right
1.1 mi · 3 min
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22
Take the ramp straight
2351 ft · 57 sec
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23
Merge slight left onto Driscoll Bypass
2.3 mi · 2 min · Driscoll Bypass
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24
Continue on U.S. Highway 77
13.2 mi · 14 min · U.S. Highway 77
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25
Merge slight left
1.4 mi · 1 min
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26
Keep slight left
1.3 km · 50 sec
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27
Continue straight
141 m · 5 sec
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28
Take the exit slight right toward Sinton, Victoria
37.6 mi · 44 min
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29
Turn slight right onto United States Highway 77
33 mi · 37 min · United States Highway 77
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30
Keep slight left to continue on Spur 91
1.5 mi · 2 min · Spur 91
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31
Merge slight left onto US Highway 59 South
88.6 mi · 1 hr 38 min · US Highway 59 South
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32
Take the exit slight right
1551 ft · 38 sec
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33
Continue on 59 Northbound Frontage Road
1.6 mi · 2 min · 59 Northbound Frontage Road
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34
Continue straight
2146 ft · 59 sec
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35
Continue on US 59 Northbound Frontage Road
2 mi · 5 min · US 59 Northbound Frontage Road
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36
Continue on Southwest Freeway Frontage Road
1.3 mi · 3 min · Southwest Freeway Frontage Road
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37
Take the ramp slight left toward I 69 North, US 59 North
1304 ft · 32 sec
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38
Merge slight left onto Southwest Freeway
32.6 mi · 38 min · Southwest Freeway
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39
Keep slight left to continue on Richmond Avenue, Downtown via Louisiana Street
1.4 km · 1 min
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40
Take the exit slight right toward Downtown, Louisiana Street
47 m · 4 sec
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41
Continue on Louisiana Street
1.9 mi · 5 min · Louisiana Street
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42
Arrive at your destination
0 m · 1 sec · Louisiana Street
Car Route Details
A richer read on the saved driving route between Port Isabel and Houston.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
U.S. Highway 77
Continue on U.S. Highway 77
102 mi · 01h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Port Isabel and Chance Showers And Thunderstorms then Mostly Cloudy near Houston.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Port Isabel to Houston?
The road trip is about 363.8 miles (585.5 km) and usually takes 05h 41m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Sinton is a useful midpoint, sitting about 185.1 miles from Port Isabel and 178.7 miles from Houston.
How much longer is the road route than the straight-line distance?
The direct path is about 278.7 miles (448.5 km), while the road route adds roughly 85.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:38 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $48.52 one way or $97.04 round trip. Estimated CO2 is about 114.1 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Port Isabel and Chance Showers And Thunderstorms then Mostly Cloudy near Houston.
Flight Path Map
This map shows the direct air route between Port Isabel and Houston. Straight-line distance: 278.72 mi (448.55 km).
#1 Port Isabel
City in Cameron County, Texas, United States
| Population | 6,226 |
| Coordinates | 26.0734100, -97.2085800 |
| Altitude | 2 |
| Country | United States |
#2 Houston
The fourth most populous city in the United States and the center of the Houston metropolitan area.
| Population | 2,316,120 |
| Coordinates | 29.7632800, -95.3632700 |
| Altitude | 12 |
| Country | United States |
End: Louisiana Street (-95.363596, 29.76347)
Estimated Travel Time
Distance: 585 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 07m |
| 40 mph (64.37 km/h) | 09h 05m |
| 50 mph (80.47 km/h) | 07h 16m |
| 60 mph (96.56 km/h) | 06h 03m |
| 70 mph (112.65 km/h) | 05h 11m |
| 80 mph (129 km/h) | 04h 32m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $48.52 | $97.04 |
| Mid-grade | $4.25 | $54.60 | $109.19 |
| Premium | $4.59 | $58.95 | $117.90 |
| Diesel | $3.99 | $51.27 | $102.54 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.