How far is Houston, TX from Port Isabel, TX?
The driving distance from Houston, TX to Port Isabel, TX is about 368.8 miles (593.5 km), with a travel time of about 07h 01m by car.
- The straight-line flight distance is about 278.7 miles (448.5 km).
- For a round trip, plan for roughly 14h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 01m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Mostly Cloudy
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Houston and Port Isabel.
Turn-by-Turn Driving Directions
Step-by-step road directions between Houston and Port Isabel.
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1
Start on Louisiana Street
45 m · 12 sec · Louisiana Street
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2
Turn left onto Congress Street
91 m · 15 sec · Congress Street
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3
Turn left onto Smith Street
2.7 mi · 6 min · Smith Street
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4
Merge slight left onto Southwest Freeway
32.8 mi · 38 min · Southwest Freeway
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5
Take the exit slight right toward Spur 10: Cottonwood, Church Road, Hartledge Road
1158 ft · 28 sec
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6
Turn straight onto Southwest Freeway Frontage Road
1.5 km · 2 min · Southwest Freeway Frontage Road
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7
Continue on Southwest Freeway Frontage Road
2217 ft · 1 min · Southwest Freeway Frontage Road
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8
Continue on US 59 Southbound Frontage Road
1.4 km · 2 min · US 59 Southbound Frontage Road
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9
Take the ramp straight
1027 ft · 25 sec
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10
Merge slight left
9.2 mi · 11 min
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11
Keep slight left
6.6 mi · 8 min
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12
Take the exit slight right
1.5 mi · 2 min
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13
Continue on US Highway 59
74.7 mi · 1 hr 22 min · US Highway 59
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14
Keep slight left to continue on Spur 91
1.6 km · 1 min · Spur 91
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15
Merge slight right onto US Highway 77 South
33.2 mi · 38 min · US Highway 77 South
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16
Turn straight onto Alamo Street
37.1 mi · 43 min · Alamo Street
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17
Take the exit straight toward I 37, US 77, I 69E
538 ft · 13 sec
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18
Keep slight left
1965 ft · 48 sec
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19
Merge slight right
2.5 mi · 2 min
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20
Take the exit slight right toward I 69E, US 77: Kingsville, Brownsville
31.3 mi · 34 min
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21
Keep slight left to continue on U.S. Highway 77
61.3 mi · 1 hr 9 min · U.S. Highway 77
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22
Keep slight left to continue on U.S. Highway 77
43.7 mi · 47 min · U.S. Highway 77
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23
Continue on North Expressway
2.1 mi · 2 min · North Expressway
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24
Keep slight right to continue on Interstate 169
3.7 mi · 4 min · Interstate 169
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25
Continue on I-169, TX 550 Toll
1.3 km · 52 sec · I-169, TX 550 Toll
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26
Continue straight
2 mi · 2 min
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27
Continue on State Highway 550
3.7 mi · 4 min · State Highway 550
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28
Turn left
1123 ft · 27 sec
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29
Merge slight left onto Brownsville-Port Isabel Highway
14.1 mi · 16 min · Brownsville-Port Isabel Highway
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30
Turn right onto State Highway 100
1 mi · 3 min · State Highway 100
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31
Turn slight right onto West Queen Isabella Boulevard
779 ft · 24 sec · West Queen Isabella Boulevard
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32
Turn right onto South Musina Street
865 ft · 25 sec · South Musina Street
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33
Arrive at your destination
0 m · 1 sec · South Musina Street
Car Route Details
A richer read on the saved driving route between Houston and Port Isabel.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US Highway 59
Continue on US Highway 59
74.7 mi · 01h 22m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Showers And Thunderstorms then Mostly Cloudy leaving Houston and Showers And Thunderstorms Likely near Port Isabel.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Houston to Port Isabel?
The road trip is about 368.8 miles (593.5 km) and usually takes 07h 01m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Sinton is a useful midpoint, sitting about 184.6 miles from Houston and 184.1 miles from Port Isabel.
How much longer is the road route than the straight-line distance?
The direct path is about 278.7 miles (448.5 km), while the road route adds roughly 90.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $49.16 one way or $98.33 round trip. Estimated CO2 is about 115.6 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Mostly Cloudy around Houston and Showers And Thunderstorms Likely near Port Isabel.
Flight Path Map
This map shows the direct air route between Houston and Port Isabel. Straight-line distance: 278.72 mi (448.55 km).
#1 Houston
The fourth most populous city in the United States and the center of the Houston metropolitan area.
| Population | 2,316,120 |
| Coordinates | 29.7632800, -95.3632700 |
| Altitude | 12 |
| Country | United States |
#2 Port Isabel
City in Cameron County, Texas, United States
| Population | 6,226 |
| Coordinates | 26.0734100, -97.2085800 |
| Altitude | 2 |
| Country | United States |
End: Port Isabel (-97.20858, 26.07341)
Estimated Travel Time
Distance: 593 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 17m |
| 40 mph (64.37 km/h) | 09h 13m |
| 50 mph (80.47 km/h) | 07h 22m |
| 60 mph (96.56 km/h) | 06h 08m |
| 70 mph (112.65 km/h) | 05h 16m |
| 80 mph (129 km/h) | 04h 36m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $49.16 | $98.33 |
| Mid-grade | $4.25 | $55.32 | $110.64 |
| Premium | $4.59 | $59.73 | $119.46 |
| Diesel | $3.99 | $51.95 | $103.90 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.