How far is Amarillo, TX from Port Isabel, TX?
The driving distance from Amarillo, TX to Port Isabel, TX is about 798.8 miles (1285.6 km), with a travel time of about 14h 06m by car.
- The straight-line flight distance is about 689 miles (1108.8 km).
- For a round trip, plan for roughly 28h 12m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 14h 06m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Areas Of Fog
Sunny
Driving Route Map
The map below follows the saved road route between Amarillo and Port Isabel.
Turn-by-Turn Driving Directions
Step-by-step road directions between Amarillo and Port Isabel.
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1
Start on East Amarillo Boulevard
87 m · 9 sec · East Amarillo Boulevard
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2
Turn right onto North Pierce Street
2278 ft · 58 sec · North Pierce Street
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3
Continue on North Pierce Street
1.5 km · 3 min · North Pierce Street
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4
Continue on Canyon Expressway
14 mi · 16 min · Canyon Expressway
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5
Keep slight left to continue on Marshall Formby Memorial Highway
103.7 mi · 1 hr 44 min · Marshall Formby Memorial Highway
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6
Take the exit slight right toward Loop 289
1011 ft · 25 sec
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7
Turn straight onto North Interstate 27
2536 ft · 1 min · North Interstate 27
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8
Turn left onto North Loop 289
1110 ft · 24 sec · North Loop 289
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9
Take the ramp slight left
885 ft · 22 sec
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10
Merge slight left
7.5 mi · 9 min
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11
Take the exit slight right toward Spur 331: Southeast Drive
128 m · 10 sec
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12
Keep slight right to continue on Spur 331: Southeast Drive
71 m · 6 sec
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13
Turn straight onto Southeast Loop 289
563 ft · 16 sec · Southeast Loop 289
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14
Turn right onto Southeast Drive
1.9 mi · 3 min · Southeast Drive
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15
Merge slight right onto Slaton Road
996 ft · 13 sec · Slaton Road
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16
Continue on East Highway 84
6.9 mi · 7 min · East Highway 84
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17
Continue on Trooper Jerry Don Davis Memorial Highway
4.5 mi · 5 min · Trooper Jerry Don Davis Memorial Highway
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18
Continue on East Highway 84
20 mi · 20 min · East Highway 84
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19
Continue on North US Highway 84
1 mi · 1 min · North US Highway 84
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20
Turn left onto East 15th Street
734 ft · 17 sec · East 15th Street
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21
Turn right onto Ralls Road
1863 ft · 38 sec · Ralls Road
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22
Turn straight onto North Avenue F
1.1 mi · 2 min · North Avenue F
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23
At the end of the road, turn left onto US Highway 84
73.9 mi · 1 hr 14 min · US Highway 84
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24
Keep slight left to continue on I 20 East, US 84 East: Abilene
6.5 mi · 7 min
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25
Take the exit slight right toward SH 70 South, SH 70 Business: Sweetwater, San Angelo
737 ft · 18 sec
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26
Turn slight left onto Southwest Georgia Avenue
624 ft · 17 sec · Southwest Georgia Avenue
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27
Turn right onto Lamar Street
1.2 km · 1 min · Lamar Street
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28
Continue on State Highway 70
10.4 mi · 11 min · State Highway 70
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29
Turn left onto State Highway 153
29.5 mi · 33 min · State Highway 153
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30
Turn right
12.3 mi · 13 min
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31
Turn left
6.3 mi · 7 min
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32
At the end of the road, turn right onto Hutchings Avenue
118 m · 18 sec · Hutchings Avenue
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33
Turn left onto South 7th Street
16.5 mi · 18 min · South 7th Street
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34
Continue on Grassmeyer Street
41.9 mi · 45 min · Grassmeyer Street
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35
Continue on Ellis Street
29.4 mi · 31 min · Ellis Street
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36
Take the exit left toward I 10 East: San Antonio
40 mi · 38 min
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37
Continue straight
54.3 mi · 55 min
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38
Keep slight right
17.4 mi · 20 min
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39
Keep slight right to continue on McDermott Freeway
1.7 mi · 2 min · McDermott Freeway
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40
Take the exit slight right toward Santa Rosa Street, Downtown
2505 ft · 1 min
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41
Turn straight onto North Pecos-La Trinidad
804 ft · 16 sec · North Pecos-La Trinidad
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42
Keep slight right to continue on North Pecos-La Trinidad
2963 ft · 1 min · North Pecos-La Trinidad
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43
Turn left onto Dolorosa Street
2725 ft · 1 min · Dolorosa Street
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44
Continue on West Market Street
1893 ft · 42 sec · West Market Street
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45
Continue on East Market Street
2143 ft · 41 sec · East Market Street
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46
Turn right onto Tower of the Americas Way
957 ft · 21 sec · Tower of the Americas Way
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47
Take the ramp slight left toward I 37 South, US 281 South
1374 ft · 34 sec
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48
Merge slight left onto William J Bordelon Freeway
1.4 mi · 2 min · William J Bordelon Freeway
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49
Continue on Lucian Adams Freeway
125.1 mi · 2 hr 7 min · Lucian Adams Freeway
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50
Take the exit slight right toward I 69E, US 77: Kingsville, Brownsville
31.3 mi · 34 min
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51
Keep slight left to continue on U.S. Highway 77
61.3 mi · 1 hr 9 min · U.S. Highway 77
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52
Keep slight left to continue on U.S. Highway 77
43.7 mi · 47 min · U.S. Highway 77
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53
Continue on North Expressway
2.1 mi · 2 min · North Expressway
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54
Keep slight right to continue on Interstate 169
3.7 mi · 4 min · Interstate 169
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55
Continue on I-169, TX 550 Toll
1.3 km · 52 sec · I-169, TX 550 Toll
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56
Continue straight
2 mi · 2 min
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57
Continue on State Highway 550
3.7 mi · 4 min · State Highway 550
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58
Turn left
1123 ft · 27 sec
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59
Merge slight left onto Brownsville-Port Isabel Highway
14.1 mi · 16 min · Brownsville-Port Isabel Highway
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60
Turn right onto State Highway 100
1 mi · 3 min · State Highway 100
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61
Turn slight right onto West Queen Isabella Boulevard
779 ft · 24 sec · West Queen Isabella Boulevard
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62
Turn right onto South Musina Street
865 ft · 25 sec · South Musina Street
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63
Arrive at your destination
0 m · 1 sec · South Musina Street
Car Route Details
A richer read on the saved driving route between Amarillo and Port Isabel.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Lucian Adams Freeway
Continue on Lucian Adams Freeway
125 mi · 02h 07m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Areas Of Fog leaving Amarillo and Sunny near Port Isabel.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Amarillo to Port Isabel?
The road trip is about 798.8 miles (1285.6 km) and usually takes 14h 06m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Junction is a useful midpoint, sitting about 399.4 miles from Amarillo and 399.4 miles from Port Isabel.
How much longer is the road route than the straight-line distance?
The direct path is about 689 miles (1108.8 km), while the road route adds roughly 109.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $108.22 one way or $216.44 round trip. Estimated CO2 is about 250.5 kg one way.
What should you check before leaving?
Before you leave, expect Areas Of Fog around Amarillo and Sunny near Port Isabel.
Flight Path Map
This map shows the direct air route between Amarillo and Port Isabel. Straight-line distance: 689 mi (1108.84 km).
#1 Amarillo
The second most populous city in Texas Panhandle.
| Population | 199,654 |
| Coordinates | 35.2220000, -101.8313000 |
| Altitude | 1118 |
| Country | United States |
#2 Port Isabel
City in Cameron County, Texas, United States
| Population | 6,226 |
| Coordinates | 26.0734100, -97.2085800 |
| Altitude | 2 |
| Country | United States |
End: Port Isabel (-97.20858, 26.07341)
Estimated Travel Time
Distance: 1286 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 26h 36m |
| 40 mph (64.37 km/h) | 19h 58m |
| 50 mph (80.47 km/h) | 15h 58m |
| 60 mph (96.56 km/h) | 13h 18m |
| 70 mph (112.65 km/h) | 11h 24m |
| 80 mph (129 km/h) | 09h 57m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.84 | $108.22 | $216.44 |
| Mid-grade | $4.35 | $122.54 | $245.08 |
| Premium | $4.72 | $133.14 | $266.28 |
| Diesel | $5.78 | $162.83 | $325.65 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Oct 15, 2026