How far is Nyssa, OR from Medford, OR?
The driving distance from Nyssa, OR to Medford, OR is about 436.5 miles (702.5 km), with a travel time of about 07h 54m by car.
- The straight-line flight distance is about 315.3 miles (507.5 km).
- For a round trip, plan for roughly 15h 49m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM MDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 54m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers
Light Rain Likely
Driving Route Map
The map below follows the saved road route between Nyssa and Medford.
Turn-by-Turn Driving Directions
Step-by-step road directions between Nyssa and Medford.
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1
Start on East Main Street
1379 ft · 23 sec · East Main Street
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2
Continue on Central Oregon Highway
7.8 mi · 12 min · Central Oregon Highway
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3
Enter the roundabout and take exit 3 toward Central Oregon Highway
128 m · 6 sec · Central Oregon Highway
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4
Exit the roundabout onto Central Oregon Highway
11.4 mi · 13 min · Central Oregon Highway
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5
Continue on Washington Street East
1.1 mi · 1 min · Washington Street East
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6
Merge slight right onto Central Oregon Highway
54.7 mi · 1 hr 42 min · Central Oregon Highway
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7
Continue on 4th Street
1725 ft · 1 min · 4th Street
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8
Continue on Central Oregon Highway
57.1 mi · 1 hr 47 min · Central Oregon Highway
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9
Continue on North Broadway Avenue
695 ft · 40 sec · North Broadway Avenue
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10
Turn right onto West D Street
86 m · 18 sec · West D Street
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11
Turn left onto North Alvord Avenue
2240 ft · 2 min · North Alvord Avenue
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12
Turn right onto West Monroe Street
1638 ft · 58 sec · West Monroe Street
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13
Continue on Hines Boulevard
1 km · 1 min · Hines Boulevard
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14
Continue on Oregon Avenue
25.8 mi · 32 min · Oregon Avenue
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15
Turn left
37.1 mi · 43 min
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16
Turn right onto Christmas Valley Highway
41.2 mi · 57 min · Christmas Valley Highway
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17
Turn left onto Old Lake Road
14.8 mi · 20 min · Old Lake Road
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18
At the end of the road, turn right onto Fremont Highway
11.3 mi · 19 min · Fremont Highway
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19
Turn left onto Bear Flat Road
14.8 mi · 20 min · Bear Flat Road
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20
Continue on Silver Lake Road
35.6 mi · 49 min · Silver Lake Road
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21
Turn left onto The Dalles-California Highway
19.6 mi · 23 min · The Dalles-California Highway
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22
Take the exit slight right toward OR 422: Chiloquin, Crater Lake
149 m · 13 sec
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23
Turn right onto Chiloquin Highway
3 mi · 4 min · Chiloquin Highway
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24
Turn right onto Crater Lake Highway
5.3 mi · 8 min · Crater Lake Highway
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25
Turn left onto Loosley Road
1.5 mi · 3 min · Loosley Road
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26
Turn right onto Weed Road East
2630 ft · 58 sec · Weed Road East
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27
Turn left onto Sevenmile Road
4.7 mi · 6 min · Sevenmile Road
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28
Continue on Westside Road
14.9 mi · 20 min · Westside Road
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29
Continue on West Side Road
1.3 mi · 2 min · West Side Road
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30
Continue on Westside Road
2680 ft · 44 sec · Westside Road
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31
At the end of the road, turn right onto Falls Highway
11.4 mi · 15 min · Falls Highway
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32
Continue on Lake of the Woods Highway
29.9 mi · 34 min · Lake of the Woods Highway
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33
Keep slight right to continue on Lake of the Woods Highway
1.1 km · 46 sec · Lake of the Woods Highway
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34
Enter the roundabout and take exit 2 toward Lake of the Woods Highway
33 m · 1 sec · Lake of the Woods Highway
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35
Exit the roundabout onto Lake of the Woods Highway
1.7 mi · 2 min · Lake of the Woods Highway
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36
Turn left onto Crater Lake Highway
2651 ft · 34 sec · Crater Lake Highway
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37
Turn right onto Rogue Valley Expressway
4.4 mi · 6 min · Rogue Valley Expressway
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38
Continue on Crater Lake Highway
1990 ft · 40 sec · Crater Lake Highway
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39
Turn left onto Poplar Drive
1.5 km · 2 min · Poplar Drive
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40
Turn right onto East McAndrews Road
916 ft · 20 sec · East McAndrews Road
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41
Turn left onto Biddle Road
156 m · 18 sec · Biddle Road
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42
Keep slight right to continue on Biddle Road
726 ft · 14 sec · Biddle Road
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43
Keep slight right to continue on Biddle Road
1147 ft · 22 sec · Biddle Road
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44
Keep slight right to continue on Biddle Road
1432 ft · 29 sec · Biddle Road
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45
Continue on East 4th Street
2182 ft · 56 sec · East 4th Street
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46
Turn left onto North Fir Street
580 ft · 16 sec · North Fir Street
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47
Arrive at your destination
0 m · 1 sec · North Fir Street
Car Route Details
A richer read on the saved driving route between Nyssa and Medford.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Central Oregon Highway
Continue on Central Oregon Highway
57.1 mi · 01h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Rain Showers leaving Nyssa and Light Rain Likely near Medford.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Nyssa to Medford?
The road trip is about 436.5 miles (702.5 km) and usually takes 07h 54m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Paisley is a useful midpoint, sitting about 208.5 miles from Nyssa and 228 miles from Medford.
How much longer is the road route than the straight-line distance?
The direct path is about 315.3 miles (507.5 km), while the road route adds roughly 121.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM MDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $76.25 one way or $152.49 round trip. Estimated CO2 is about 136.9 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Nyssa and Medford, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Rain Showers around Nyssa and Light Rain Likely near Medford.
Stop Ideas Near Paisley
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Paisley.
Klamath Falls station
Chemult
Klamath Falls, OR
Flight Path Map
This map shows the direct air route between Nyssa and Medford. Straight-line distance: 315.33 mi (507.47 km).
#1 Nyssa
City in Malheur County, Oregon, United States
| Population | 3,231 |
| Coordinates | 43.8768300, -116.9948800 |
| Altitude | 664 |
| Country | United States |
#2 Medford
The most populous city in Jackson County, Oregon.
| Population | 83,412 |
| Coordinates | 42.3265200, -122.8755900 |
| Altitude | 421 |
| Country | United States |
End: North Fir Street (-122.875345, 42.326645)
Estimated Travel Time
Distance: 703 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 14h 32m |
| 40 mph (64.37 km/h) | 10h 54m |
| 50 mph (80.47 km/h) | 08h 43m |
| 60 mph (96.56 km/h) | 07h 16m |
| 70 mph (112.65 km/h) | 06h 14m |
| 80 mph (129 km/h) | 05h 26m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.95 | $76.25 | $152.49 |
| Mid-grade | $5.34 | $82.21 | $164.41 |
| Premium | $5.57 | $85.72 | $171.43 |
| Diesel | $6.37 | $98.04 | $196.07 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Oregon · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.