How far is Medford, OR from Nyssa, OR?
The driving distance from Medford, OR to Nyssa, OR is about 417.7 miles (672.2 km), with a travel time of about 10h 14m by car.
- The straight-line flight distance is about 315.3 miles (507.5 km).
- For a round trip, plan for roughly 20h 28m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM PDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 10h 14m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Oregon, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Light Rain Likely
Rain Showers
Driving Route Map
The map below follows the saved road route between Medford and Nyssa.
Turn-by-Turn Driving Directions
Step-by-step road directions between Medford and Nyssa.
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1
Start on North Fir Street
580 ft · 18 sec · North Fir Street
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2
Turn right onto West 4th Street
2226 ft · 54 sec · West 4th Street
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3
Continue on Biddle Road
1.3 mi · 2 min · Biddle Road
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4
Take the ramp right
1221 ft · 36 sec
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5
Merge slight left onto Crater Lake Highway
2251 ft · 52 sec · Crater Lake Highway
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6
Turn straight onto Rogue Valley Expressway
4.5 mi · 6 min · Rogue Valley Expressway
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7
At the end of the road, turn left onto Crater Lake Highway
2826 ft · 39 sec · Crater Lake Highway
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8
Turn right onto Lake of the Woods Highway
1.7 mi · 2 min · Lake of the Woods Highway
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9
Enter the roundabout and take exit 2 toward Lake of the Woods Highway
37 m · 2 sec · Lake of the Woods Highway
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10
Exit the roundabout onto Lake of the Woods Highway
2785 ft · 36 sec · Lake of the Woods Highway
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11
Keep slight right to continue on Lake of the Woods Highway
30 mi · 34 min · Lake of the Woods Highway
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12
Continue on Falls Highway
11.4 mi · 16 min · Falls Highway
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13
Turn left onto Westside Road
2680 ft · 42 sec · Westside Road
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14
Continue on West Side Road
1.3 mi · 2 min · West Side Road
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15
Continue on Westside Road
14.9 mi · 20 min · Westside Road
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16
Continue on Sevenmile Road
4.7 mi · 7 min · Sevenmile Road
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17
At the end of the road, turn right onto Weed Road East
2630 ft · 58 sec · Weed Road East
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18
Turn left onto Loosley Road
1.5 mi · 3 min · Loosley Road
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19
Turn right onto Crater Lake Highway
5.3 mi · 8 min · Crater Lake Highway
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20
Turn left onto Chiloquin Highway
3.1 mi · 4 min · Chiloquin Highway
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21
Take the ramp left
1348 ft · 37 sec
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22
Merge slight left onto The Dalles-California Highway
19.5 mi · 23 min · The Dalles-California Highway
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23
Turn right onto Silver Lake Road
35.6 mi · 49 min · Silver Lake Road
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24
Continue on Bear Flat Road
14.8 mi · 20 min · Bear Flat Road
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25
Turn right onto Fremont Highway
11.3 mi · 19 min · Fremont Highway
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26
Turn left onto Old Lake Road
14.8 mi · 20 min · Old Lake Road
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27
Turn right onto Christmas Valley Highway
41.2 mi · 57 min · Christmas Valley Highway
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28
At the end of the road, turn left
37.1 mi · 43 min
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29
Continue on Central Oregon Highway
25.8 mi · 32 min · Central Oregon Highway
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30
Continue on Hines Boulevard
1 km · 1 min · Hines Boulevard
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31
Continue on West Monroe Street
1638 ft · 1 min · West Monroe Street
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32
Turn left onto North Alvord Avenue
2240 ft · 2 min · North Alvord Avenue
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33
Turn right onto West D Street
86 m · 18 sec · West D Street
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34
Turn left onto North Broadway Avenue
695 ft · 38 sec · North Broadway Avenue
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35
Turn straight onto Seneca Drive
57.1 mi · 1 hr 47 min · Seneca Drive
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36
Continue on 4th Street
1725 ft · 1 min · 4th Street
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37
Continue on Central Oregon Highway
54.8 mi · 1 hr 42 min · Central Oregon Highway
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38
Continue on A Street West
1.6 km · 1 min · A Street West
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39
Merge slight left onto Central Oregon Highway
11.4 mi · 13 min · Central Oregon Highway
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40
Enter the roundabout and take exit 1 toward Central Oregon Highway
14 m · 1 sec · Central Oregon Highway
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41
Exit the roundabout onto Central Oregon Highway
7.8 mi · 12 min · Central Oregon Highway
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42
Continue on Main Street
1398 ft · 24 sec · Main Street
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43
Arrive at your destination
0 m · 1 sec · East Main Street
Car Route Details
A richer read on the saved driving route between Medford and Nyssa.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Seneca Drive
Turn straight onto Seneca Drive
57.1 mi · 01h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Light Rain Likely leaving Medford and Rain Showers near Nyssa.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Medford to Nyssa?
The road trip is about 417.7 miles (672.2 km) and usually takes 10h 14m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Paisley is a useful midpoint, sitting about 208.5 miles from Medford and 209.2 miles from Nyssa.
How much longer is the road route than the straight-line distance?
The direct path is about 315.3 miles (507.5 km), while the road route adds roughly 102.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM PDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $72.98 one way or $145.96 round trip. Estimated CO2 is about 131 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Medford and Nyssa, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Light Rain Likely around Medford and Rain Showers near Nyssa.
Stop Ideas Near Paisley
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Paisley.
Klamath Falls station
Chemult
Klamath Falls, OR
Flight Path Map
This map shows the direct air route between Medford and Nyssa. Straight-line distance: 315.33 mi (507.47 km).
#1 Medford
The most populous city in Jackson County, Oregon.
| Population | 83,412 |
| Coordinates | 42.3265200, -122.8755900 |
| Altitude | 421 |
| Country | United States |
#2 Nyssa
City in Malheur County, Oregon, United States
| Population | 3,231 |
| Coordinates | 43.8768300, -116.9948800 |
| Altitude | 664 |
| Country | United States |
End: Nyssa (-116.99488, 43.87683)
Estimated Travel Time
Distance: 672 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 55m |
| 40 mph (64.37 km/h) | 10h 26m |
| 50 mph (80.47 km/h) | 08h 21m |
| 60 mph (96.56 km/h) | 06h 57m |
| 70 mph (112.65 km/h) | 05h 58m |
| 80 mph (129 km/h) | 05h 12m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.95 | $72.98 | $145.96 |
| Mid-grade | $5.34 | $78.68 | $157.36 |
| Premium | $5.57 | $82.04 | $164.09 |
| Diesel | $6.37 | $93.83 | $187.67 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Oregon · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.