How far is Mayo, FL from Jacksonville, FL?
The driving distance from Mayo, FL to Jacksonville, FL is about 105.8 miles (170.3 km), with a travel time of about 01h 43m by car.
- The straight-line flight distance is about 92.8 miles (149.3 km).
- For a round trip, plan for roughly 03h 27m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 43m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat of Columbia County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Partly Cloudy
Driving Route Map
The map below follows the saved road route between Mayo and Jacksonville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mayo and Jacksonville.
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1
Start on Main Street
43 m · 8 sec · Main Street
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2
Turn right onto North Fletcher Avenue
20.7 mi · 27 min · North Fletcher Avenue
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3
Enter the roundabout and take exit 2 toward 11th Street Southwest
47 m · 4 sec · 11th Street Southwest
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4
Exit the roundabout onto 11th Street Southwest
933 ft · 24 sec · 11th Street Southwest
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5
Turn left onto Houston Avenue Southwest
3202 ft · 1 min · Houston Avenue Southwest
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6
Continue on Houston Avenue Northwest
2777 ft · 59 sec · Houston Avenue Northwest
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7
Turn right onto Winderweedle Street Northwest
1699 ft · 50 sec · Winderweedle Street Northwest
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8
Turn left onto Ohio Avenue
1.9 mi · 3 min · Ohio Avenue
-
9
Take the ramp slight right
1700 ft · 41 sec
-
10
Merge slight left
78.4 mi · 1 hr 26 min
-
11
Take the exit slight left toward I 95 South: Jacksonville Beaches, Daytona Beach
2176 ft · 34 sec
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12
Keep slight left to continue on I 95 North: International Airport, Savannah
1.1 km · 57 sec
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13
Merge slight left
1.2 km · 1 min
-
14
Take the exit slight right toward Union Street, Beaver Street
916 ft · 26 sec
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15
Turn straight onto Union Street
1.2 km · 2 min · Union Street
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16
Arrive at your destination
0 m · 1 sec · Union Street
Car Route Details
A richer read on the saved driving route between Mayo and Jacksonville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Ohio Avenue
Merge slight left
78.4 mi · 01h 26m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Chance Showers And Thunderstorms leaving Mayo and Partly Cloudy near Jacksonville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mayo to Jacksonville?
The road trip is about 105.8 miles (170.3 km) and usually takes 01h 43m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Lake City is a useful midpoint, sitting about 52.9 miles from Mayo and 53 miles from Jacksonville.
How much longer is the road route than the straight-line distance?
The direct path is about 92.8 miles (149.3 km), while the road route adds roughly 13 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 3:02 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.51 one way or $31.03 round trip. Estimated CO2 is about 33.2 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Mayo and Partly Cloudy near Jacksonville.
Stop Ideas Near Lake City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Lake City.
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Flight Path Map
This map shows the direct air route between Mayo and Jacksonville. Straight-line distance: 92.75 mi (149.27 km).
#1 Mayo
Municipality in Lafayette, Florida, USA
| Population | 1,289 |
| Coordinates | 30.0530000, -83.1748600 |
| Altitude | 27 |
| Country | United States |
#2 Jacksonville
The thirteenth most populous city in the United States and the center of the Jacksonville metropolitan area.
| Population | 920,570 |
| Coordinates | 30.3321800, -81.6556500 |
| Altitude | 5 |
| Country | United States |
End: Union Street (-81.655668, 30.332118)
Estimated Travel Time
Distance: 170 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 31m |
| 40 mph (64.37 km/h) | 02h 38m |
| 50 mph (80.47 km/h) | 02h 06m |
| 60 mph (96.56 km/h) | 01h 45m |
| 70 mph (112.65 km/h) | 01h 30m |
| 80 mph (129 km/h) | 01h 19m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $15.51 | $31.03 |
| Mid-grade | $4.60 | $17.19 | $34.38 |
| Premium | $4.90 | $18.31 | $36.62 |
| Diesel | $4.35 | $16.27 | $32.54 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.