How far is Mayo, FL from Fort Lauderdale, FL?
The driving distance from Mayo, FL to Fort Lauderdale, FL is about 371.5 miles (597.9 km), with a travel time of about 07h 01m by car.
- The straight-line flight distance is about 328.5 miles (528.6 km).
- For a round trip, plan for roughly 14h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 01m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Osceola County, Florida.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Mostly Sunny then Slight Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Mayo and Fort Lauderdale.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mayo and Fort Lauderdale.
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1
Start on Main Street
1.1 km · 1 min · Main Street
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2
Continue on US Highway 27
40.3 mi · 54 min · US Highway 27
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3
Continue on Northeast 1st Avenue
3011 ft · 1 min · Northeast 1st Avenue
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4
Turn right onto Santa Fe Boulevard
1.4 km · 1 min · Santa Fe Boulevard
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5
Continue on ML King Memorial Highway
3.8 mi · 5 min · ML King Memorial Highway
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6
Take the ramp slight right toward I 75 South: Tampa
1.3 km · 1 min
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7
Merge slight left
70.8 mi · 1 hr 16 min
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8
Take the exit slight left toward Florida's Turnpike South, Orlando
240.6 mi · 4 hr 20 min · Florida's Turnpike
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9
Take the exit slight right toward Coconut Creek Parkway, Martin Luther King Boulevard
1 km · 2 min
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10
Keep slight left to continue on East Martin Luther King Boulevard, Atlantic Boulevard
77 m · 15 sec
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11
Turn left onto Dr. Martin Luther King Boulevard
1.4 mi · 3 min · Dr. Martin Luther King Boulevard
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12
Turn left onto Northwest 16th Avenue
696 ft · 25 sec · Northwest 16th Avenue
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13
Turn right onto North Andrews Avenue
3159 ft · 1 min · North Andrews Avenue
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14
Turn left onto West Atlantic Boulevard
151 m · 17 sec · West Atlantic Boulevard
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15
Take the ramp slight right toward I 95 South: Miami
2315 ft · 58 sec
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16
Merge slight left
7.2 mi · 8 min
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17
Take the exit slight right toward SR 842: Broward Boulevard, Downtown
2709 ft · 1 min
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18
Turn left onto West Broward Boulevard
1.8 mi · 4 min · West Broward Boulevard
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19
Continue on East Broward Boulevard
988 ft · 35 sec · East Broward Boulevard
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20
Arrive at your destination
0 m · 1 sec · East Broward Boulevard
Car Route Details
A richer read on the saved driving route between Mayo and Fort Lauderdale.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Take the exit slight left toward Florida's Turnpike South, Orlando
241 mi · 04h 20m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Chance Showers And Thunderstorms leaving Mayo and Mostly Sunny then Slight Chance Showers And Thunderstorms near Fort Lauderdale.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mayo to Fort Lauderdale?
The road trip is about 371.5 miles (597.9 km) and usually takes 07h 01m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Saint Cloud is a useful midpoint, sitting about 186 miles from Mayo and 185.5 miles from Fort Lauderdale.
How much longer is the road route than the straight-line distance?
The direct path is about 328.5 miles (528.6 km), while the road route adds roughly 43 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $54.38 one way or $108.76 round trip. Estimated CO2 is about 116.5 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around Mayo and Mostly Sunny then Slight Chance Showers And Thunderstorms near Fort Lauderdale.
Stop Ideas Near Saint Cloud
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Cloud.
Kissimmee
Orlando Health/Amtrak
Winter Park
Winter Haven
Flight Path Map
This map shows the direct air route between Mayo and Fort Lauderdale. Straight-line distance: 328.45 mi (528.59 km).
#1 Mayo
Municipality in Lafayette, Florida, USA
| Population | 1,289 |
| Coordinates | 30.0530000, -83.1748600 |
| Altitude | 27 |
| Country | United States |
#2 Fort Lauderdale
The second most populous city in Broward County, Florida.
| Population | 184,245 |
| Coordinates | 26.1223100, -80.1433800 |
| Altitude | 1 |
| Country | United States |
End: Fort Lauderdale (-80.14338, 26.12231)
Estimated Travel Time
Distance: 598 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 22m |
| 40 mph (64.37 km/h) | 09h 17m |
| 50 mph (80.47 km/h) | 07h 25m |
| 60 mph (96.56 km/h) | 06h 11m |
| 70 mph (112.65 km/h) | 05h 18m |
| 80 mph (129 km/h) | 04h 38m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $54.38 | $108.76 |
| Mid-grade | $4.60 | $60.25 | $120.51 |
| Premium | $4.90 | $64.19 | $128.37 |
| Diesel | $4.35 | $57.03 | $114.06 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 26, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.