How far is Key Largo, FL from Tallahassee, FL?
The driving distance from Key Largo, FL to Tallahassee, FL is about 546.9 miles (880.1 km), with a travel time of about 08h 21m by car.
- The straight-line flight distance is about 437.7 miles (704.4 km).
- For a round trip, plan for roughly 16h 42m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 08h 21m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Osceola County, Florida.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers
Mostly Cloudy then Patchy Fog
Driving Route Map
The map below follows the saved road route between Key Largo and Tallahassee.
Turn-by-Turn Driving Directions
Step-by-step road directions between Key Largo and Tallahassee.
-
1
Start on Harbor Drive
94 m · 16 sec · Harbor Drive
-
2
Turn right onto Overseas Highway
9.3 mi · 16 min · Overseas Highway
-
3
Continue on Dixie Highway
19.4 mi · 27 min · Dixie Highway
-
4
Take the exit slight right toward Miami, Orlando, Florida's Turnpike North
1785 ft · 38 sec
-
5
Continue on Homestead Extension of Florida's Turnpike
13.2 mi · 16 min · Homestead Extension of Florida's Turnpike
-
6
Keep slight right to continue on Homestead Extension of Florida's Turnpike
3.6 mi · 5 min · Homestead Extension of Florida's Turnpike
-
7
Keep slight left to continue on Homestead Extension of Florida's Turnpike
2.5 mi · 3 min · Homestead Extension of Florida's Turnpike
-
8
Keep slight right to continue on Homestead Extension of Florida's Turnpike
27.1 mi · 30 min · Homestead Extension of Florida's Turnpike
-
9
Keep slight right to continue on Homestead Extension of Florida's Turnpike
1 mi · 1 min · Homestead Extension of Florida's Turnpike
-
10
Merge slight left onto Florida's Turnpike
260.5 mi · 4 hr 43 min · Florida's Turnpike
-
11
Keep slight left to continue on Florida's Turnpike
1281 ft · 16 sec · Florida's Turnpike
-
12
Merge slight left
106.9 mi · 1 hr 55 min
-
13
Take the exit slight right toward I 10: Jacksonville, Tallahassee
820 ft · 16 sec
-
14
Keep slight left to continue on I 10 West: Tallahassee
1569 ft · 30 sec
-
15
Merge slight right
87.7 mi · 1 hr 34 min
-
16
Turn left onto Mahan Drive
6.7 mi · 12 min · Mahan Drive
-
17
Continue on East Tennessee Street
3252 ft · 1 min · East Tennessee Street
-
18
Turn left onto North Franklin Boulevard
2568 ft · 1 min · North Franklin Boulevard
-
19
Turn right onto East Pensacola Street
1087 ft · 40 sec · East Pensacola Street
-
20
Turn left onto South Calhoun Street
64 m · 10 sec · South Calhoun Street
-
21
Turn right onto Apalachee Parkway
103 m · 12 sec · Apalachee Parkway
-
22
Turn right onto South Monroe Street
9 m · 1 sec · South Monroe Street
-
23
Arrive at your destination
0 m · 1 sec · South Monroe Street
Car Route Details
A richer read on the saved driving route between Key Largo and Tallahassee.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Merge slight left onto Florida's Turnpike
261 mi · 04h 43m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Slight Chance Rain Showers leaving Key Largo and Mostly Cloudy then Patchy Fog near Tallahassee.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Key Largo to Tallahassee?
The road trip is about 546.9 miles (880.1 km) and usually takes 08h 21m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Saint Cloud is a useful midpoint, sitting about 270.5 miles from Key Largo and 276.3 miles from Tallahassee.
How much longer is the road route than the straight-line distance?
The direct path is about 437.7 miles (704.4 km), while the road route adds roughly 109.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $80.06 one way or $160.11 round trip. Estimated CO2 is about 171.5 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Rain Showers around Key Largo and Mostly Cloudy then Patchy Fog near Tallahassee.
Stop Ideas Near Saint Cloud
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Cloud.
Kissimmee
Orlando Health/Amtrak
Winter Park
Winter Haven
Flight Path Map
This map shows the direct air route between Key Largo and Tallahassee. Straight-line distance: 437.71 mi (704.42 km).
#1 Key Largo
Census designated place in Florida, United States
| Population | 10,433 |
| Coordinates | 25.0865200, -80.4472800 |
| Altitude | 2 |
| Country | United States |
#2 Tallahassee
The capital of Florida.
| Population | 196,326 |
| Coordinates | 30.4382600, -84.2807300 |
| Altitude | 62 |
| Country | United States |
End: South Monroe Street (-84.280628, 30.438261)
Estimated Travel Time
Distance: 880 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 18h 13m |
| 40 mph (64.37 km/h) | 13h 40m |
| 50 mph (80.47 km/h) | 10h 56m |
| 60 mph (96.56 km/h) | 09h 06m |
| 70 mph (112.65 km/h) | 07h 48m |
| 80 mph (129 km/h) | 06h 49m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $80.06 | $160.11 |
| Mid-grade | $4.60 | $88.70 | $177.41 |
| Premium | $4.90 | $94.49 | $188.99 |
| Diesel | $4.35 | $83.96 | $167.91 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 07, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.