How far is Key Largo, FL from Cape Coral, FL?
The driving distance from Key Largo, FL to Cape Coral, FL is about 187.4 miles (301.6 km), with a travel time of about 03h 34m by car.
- The straight-line flight distance is about 138.3 miles (222.6 km).
- For a round trip, plan for roughly 07h 08m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 34m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Broward County, Florida.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Key Largo and Cape Coral.
Turn-by-Turn Driving Directions
Step-by-step road directions between Key Largo and Cape Coral.
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1
Start on Harbor Drive
94 m · 16 sec · Harbor Drive
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2
Turn right onto Overseas Highway
9.3 mi · 16 min · Overseas Highway
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3
Continue on Dixie Highway
19.4 mi · 27 min · Dixie Highway
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4
Take the exit slight right toward Miami, Orlando, Florida's Turnpike North
1785 ft · 38 sec
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5
Continue on Homestead Extension of Florida's Turnpike
13.2 mi · 16 min · Homestead Extension of Florida's Turnpike
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6
Keep slight right to continue on Homestead Extension of Florida's Turnpike
3.6 mi · 5 min · Homestead Extension of Florida's Turnpike
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7
Keep slight left to continue on Homestead Extension of Florida's Turnpike
2.5 mi · 3 min · Homestead Extension of Florida's Turnpike
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8
Keep slight right to continue on Homestead Extension of Florida's Turnpike
15.5 mi · 18 min · Homestead Extension of Florida's Turnpike
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9
Take the exit slight right toward US 27: Okeechobee Road
1140 ft · 28 sec
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10
Keep slight right to continue on US 27: Okeechobee Road
633 ft · 16 sec
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11
Merge slight left onto Okeechobee Road
17.6 mi · 23 min · Okeechobee Road
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12
Take the exit slight right toward I 75: Miami, Fort Lauderdale, Naples
1360 ft · 33 sec
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13
Keep slight left to continue on I 75 North: Naples
1.3 km · 2 min
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14
Merge slight left onto Alligator Alley
106.6 mi · 1 hr 54 min · Alligator Alley
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15
Take the exit slight right toward CR 876: Cape Coral
1765 ft · 43 sec
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16
Keep slight left to continue on CR 876 West: Lee County Sports Complex, Florida SouthWestern State College, Cape Coral
160 m · 17 sec
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17
Turn left onto CR 876 West
35 m · 5 sec
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18
Turn left onto Daniels Parkway
4.8 mi · 8 min · Daniels Parkway
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19
Turn right onto South Cleveland Avenue
1.1 km · 1 min · South Cleveland Avenue
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20
Turn left onto College Parkway
3.2 mi · 6 min · College Parkway
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21
Continue on Cape Coral Bridge Road
1.1 km · 1 min · Cape Coral Bridge Road
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22
Continue on Cape Coral Parkway East
1 mi · 2 min · Cape Coral Parkway East
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23
Turn right
61 m · 15 sec
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24
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Key Largo and Cape Coral.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Alligator Alley
Merge slight left onto Alligator Alley
107 mi · 01h 54m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Rain Showers leaving Key Largo and Mostly Sunny near Cape Coral.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Key Largo to Cape Coral?
The road trip is about 187.4 miles (301.6 km) and usually takes 03h 34m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Weston is a useful midpoint, sitting about 100.3 miles from Key Largo and 87.1 miles from Cape Coral.
How much longer is the road route than the straight-line distance?
The direct path is about 138.3 miles (222.6 km), while the road route adds roughly 49.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 9:52 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $27.42 one way or $54.84 round trip. Estimated CO2 is about 58.7 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Rain Showers around Key Largo and Mostly Sunny near Cape Coral.
Stop Ideas Near Weston
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Weston.
Fort Lauderdale
Hollywood
Miami Intermodal Center
Deerfield Beach
Flight Path Map
This map shows the direct air route between Key Largo and Cape Coral. Straight-line distance: 138.32 mi (222.61 km).
#1 Key Largo
Census designated place in Florida, United States
| Population | 10,433 |
| Coordinates | 25.0865200, -80.4472800 |
| Altitude | 2 |
| Country | United States |
#2 Cape Coral
The second most populous city in Lee County, Florida.
| Population | 200,972 |
| Coordinates | 26.5628500, -81.9495300 |
| Altitude | 1 |
| Country | United States |
End: (-81.94953, 26.562855)
Estimated Travel Time
Distance: 302 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 14m |
| 40 mph (64.37 km/h) | 04h 41m |
| 50 mph (80.47 km/h) | 03h 44m |
| 60 mph (96.56 km/h) | 03h 07m |
| 70 mph (112.65 km/h) | 02h 40m |
| 80 mph (129 km/h) | 02h 20m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $27.42 | $54.84 |
| Mid-grade | $4.60 | $30.38 | $60.76 |
| Premium | $4.90 | $32.36 | $64.73 |
| Diesel | $4.35 | $28.75 | $57.51 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 07, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.