How far is Tallahassee, FL from Key Largo, FL?
The driving distance from Tallahassee, FL to Key Largo, FL is about 540.4 miles (869.7 km), with a travel time of about 10h 07m by car.
- The straight-line flight distance is about 437.7 miles (704.4 km).
- For a round trip, plan for roughly 20h 14m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 10h 07m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
A city in Osceola County, Florida.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy then Patchy Fog
Slight Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Tallahassee and Key Largo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tallahassee and Key Largo.
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1
Start on South Monroe Street
55 m · 8 sec · South Monroe Street
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2
Turn right onto East Pensacola Street
1428 ft · 47 sec · East Pensacola Street
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3
Turn left onto South Franklin Boulevard
2557 ft · 1 min · South Franklin Boulevard
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4
Turn right onto East Tennessee Street
3230 ft · 1 min · East Tennessee Street
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5
Continue on Mahan Drive
6.5 mi · 12 min · Mahan Drive
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6
Take the ramp slight right toward I 10 East: Lake City
1.1 km · 1 min
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7
Merge slight left
86.9 mi · 1 hr 33 min
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8
Take the exit slight right toward I-75 South: Tampa
1959 ft · 37 sec
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9
Merge slight left
107.2 mi · 1 hr 55 min
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10
Take the exit slight left toward Florida's Turnpike South, Orlando
261 mi · 4 hr 43 min · Florida's Turnpike
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11
Take the exit slight right toward Florida's Turnpike Toll South, Homestead
1197 ft · 20 sec · Homestead Extension of Florida's Turnpike
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12
Keep slight left to continue on Homestead Extension of Florida's Turnpike
46.9 mi · 54 min · Homestead Extension of Florida's Turnpike
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13
Keep slight left
2930 ft · 1 min
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14
Merge slight left onto Dixie Highway
19.2 mi · 27 min · Dixie Highway
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15
Continue on Overseas Highway
9.3 mi · 16 min · Overseas Highway
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16
Continue on Overseas Highway
138 m · 28 sec · Overseas Highway
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17
Turn right onto Harbor Drive
94 m · 14 sec · Harbor Drive
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18
Arrive at your destination
0 m · 1 sec · Harbor Drive
Car Route Details
A richer read on the saved driving route between Tallahassee and Key Largo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Take the exit slight left toward Florida's Turnpike South, Orlando
261 mi · 04h 43m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Cloudy then Patchy Fog leaving Tallahassee and Slight Chance Rain Showers near Key Largo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tallahassee to Key Largo?
The road trip is about 540.4 miles (869.7 km) and usually takes 10h 07m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Saint Cloud is a useful midpoint, sitting about 270.5 miles from Tallahassee and 269.9 miles from Key Largo.
How much longer is the road route than the straight-line distance?
The direct path is about 437.7 miles (704.4 km), while the road route adds roughly 102.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $79.10 one way or $158.20 round trip. Estimated CO2 is about 169.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy then Patchy Fog around Tallahassee and Slight Chance Rain Showers near Key Largo.
Stop Ideas Near Saint Cloud
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Cloud.
Kissimmee
Orlando Health/Amtrak
Winter Park
Winter Haven
Flight Path Map
This map shows the direct air route between Tallahassee and Key Largo. Straight-line distance: 437.71 mi (704.42 km).
#1 Tallahassee
The capital of Florida.
| Population | 196,326 |
| Coordinates | 30.4382600, -84.2807300 |
| Altitude | 62 |
| Country | United States |
#2 Key Largo
Census designated place in Florida, United States
| Population | 10,433 |
| Coordinates | 25.0865200, -80.4472800 |
| Altitude | 2 |
| Country | United States |
End: Key Largo (-80.44728, 25.08652)
Estimated Travel Time
Distance: 870 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 18h 00m |
| 40 mph (64.37 km/h) | 13h 30m |
| 50 mph (80.47 km/h) | 10h 48m |
| 60 mph (96.56 km/h) | 09h 00m |
| 70 mph (112.65 km/h) | 07h 43m |
| 80 mph (129 km/h) | 06h 44m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $79.10 | $158.20 |
| Mid-grade | $4.60 | $87.65 | $175.29 |
| Premium | $4.90 | $93.37 | $186.73 |
| Diesel | $4.35 | $82.95 | $165.91 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 07, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.