How far is Sanford, ME from Palermo, ME?
The driving distance from Sanford, ME to Palermo, ME is about 108.8 miles (175.1 km), with a travel time of about 02h 16m by car.
- The straight-line flight distance is about 93.1 miles (149.8 km).
- For a round trip, plan for roughly 04h 32m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 16m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Maine, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Patchy Fog
Driving Route Map
The map below follows the saved road route between Sanford and Palermo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Sanford and Palermo.
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1
Start on the route
27 m · 8 sec
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2
Turn right onto Washington Street
763 ft · 23 sec · Washington Street
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3
Continue on River Street
872 ft · 26 sec · River Street
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4
Turn right onto Cottage Street
1.2 mi · 3 min · Cottage Street
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5
Continue on Sanford Road
2.4 mi · 4 min · Sanford Road
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6
Continue on Biddeford Road
1.8 mi · 2 min · Biddeford Road
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7
Continue on Alfred Road
8.2 mi · 9 min · Alfred Road
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8
Continue on Alfred Street
1.4 mi · 2 min · Alfred Street
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9
Take the ramp left
735 ft · 1 min
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10
Keep slight right to continue on I 95 North Toll: Portland, Augusta
1317 ft · 33 sec
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11
Merge slight left onto Maine Turnpike
12.2 mi · 13 min · Maine Turnpike
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12
Keep slight right to continue on Downtown Portland
52.5 mi · 1 hr 1 min
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13
Merge slight left onto Maine Turnpike
9.8 mi · 11 min · Maine Turnpike
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14
Take the exit slight right toward ME 3: Augusta, Belfast
767 ft · 26 sec
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15
Keep slight right
834 ft · 20 sec
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16
Merge slight left onto Augusta Bypass
2.5 mi · 4 min · Augusta Bypass
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17
Continue on North Belfast Avenue
8.1 mi · 12 min · North Belfast Avenue
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18
Continue on Belfast Road
1077 ft · 17 sec · Belfast Road
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19
Continue on Route 3
6.7 mi · 9 min · Route 3
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20
Turn left onto Branch Mills Road
1.2 km · 3 min · Branch Mills Road
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21
Arrive at your destination
0 m · 1 sec · Branch Mills Road
Car Route Details
A richer read on the saved driving route between Sanford and Palermo.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Downtown Portland
Keep slight right to continue on Downtown Portland
52.5 mi · 01h 01m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Partly Cloudy leaving Sanford and Chance Rain Showers then Patchy Fog near Palermo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Sanford to Palermo?
The road trip is about 108.8 miles (175.1 km) and usually takes 02h 16m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Freeport is a useful midpoint, sitting about 54.4 miles from Sanford and 54.4 miles from Palermo.
How much longer is the road route than the straight-line distance?
The direct path is about 93.1 miles (149.8 km), while the road route adds roughly 15.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 1:58 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.15 one way or $30.30 round trip. Estimated CO2 is about 34.1 kg one way.
What should you check before leaving?
Before you leave, expect Partly Cloudy around Sanford and Chance Rain Showers then Patchy Fog near Palermo.
Stop Ideas Near Freeport
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Freeport.
Freeport
Brunswick Maine Street Station
Bath, Maine
Portland Transportation Center
Flight Path Map
This map shows the direct air route between Sanford and Palermo. Straight-line distance: 93.09 mi (149.81 km).
#1 Sanford
City in York County, Maine, United States
| Population | 21,253 |
| Coordinates | 43.4392500, -70.7742200 |
| Altitude | 92 |
| Country | United States |
#2 Palermo
Town in Waldo County, Maine, United States of America
| Population | 1,525 |
| Coordinates | 44.4078500, -69.4739300 |
| Altitude | 111 |
| Country | United States |
End: Palermo (-69.47393, 44.40785)
Estimated Travel Time
Distance: 175 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 37m |
| 40 mph (64.37 km/h) | 02h 43m |
| 50 mph (80.47 km/h) | 02h 10m |
| 60 mph (96.56 km/h) | 01h 48m |
| 70 mph (112.65 km/h) | 01h 33m |
| 80 mph (129 km/h) | 01h 21m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.95 | $15.15 | $30.30 |
| Mid-grade | $4.46 | $17.11 | $34.23 |
| Premium | $4.86 | $18.65 | $37.31 |
| Diesel | $6.00 | $23.03 | $46.06 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Maine · Apr 16, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.