How far is Palermo, ME from Sanford, ME?
The driving distance from Palermo, ME to Sanford, ME is about 110 miles (177.1 km), with a travel time of about 01h 57m by car.
- The straight-line flight distance is about 93.1 miles (149.8 km).
- For a round trip, plan for roughly 03h 54m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 57m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Maine, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Rain Showers then Patchy Fog
Partly Cloudy
Driving Route Map
The map below follows the saved road route between Palermo and Sanford.
Turn-by-Turn Driving Directions
Step-by-step road directions between Palermo and Sanford.
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1
Start on Branch Mills Road
1.2 km · 3 min · Branch Mills Road
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2
At the end of the road, turn right
15 mi · 21 min
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3
Turn left onto North Belfast Avenue
1.6 km · 2 min · North Belfast Avenue
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4
At the end of the road, turn left onto Bangor Street
2936 ft · 53 sec · Bangor Street
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5
Enter the roundabout and take exit 2 toward Cony Circle
49 m · 3 sec · Memorial Drive
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6
Exit the rotary onto Memorial Drive
1.1 km · 2 min · Memorial Drive
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7
Enter the roundabout and take exit 3 toward Memorial Circle
122 m · 7 sec · State Street
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8
Exit the rotary onto State Street
1007 ft · 19 sec · State Street
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9
Turn right onto Capitol Street
1.3 km · 1 min · Capitol Street
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10
Turn straight onto Armory Street
915 ft · 20 sec · Armory Street
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11
Turn left onto Western Avenue
1.1 km · 1 min · Western Avenue
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12
Take the exit slight right toward I 95: Portland, Waterville, Bangor
1829 ft · 44 sec
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13
Keep slight left to continue on I-95 South: Portland, Kittery
3262 ft · 1 min
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14
Merge slight left onto Maine Turnpike
5.9 mi · 6 min · Maine Turnpike
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15
Keep slight right to continue on I 295 South, ME 9, ME 126: Gardiner, Brunswick
50.5 mi · 59 min
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16
Keep slight left
2.6 mi · 4 min
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17
Merge slight left onto Maine Turnpike
11.6 mi · 12 min · Maine Turnpike
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18
Take the exit slight right toward ME 111: Biddeford
1.2 km · 2 min
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19
Turn right onto Alfred Street
1.4 mi · 2 min · Alfred Street
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20
Continue on Alfred Road
8.2 mi · 9 min · Alfred Road
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21
Continue on Biddeford Road
1.8 mi · 2 min · Biddeford Road
-
22
Continue on Sanford Road
2.4 mi · 4 min · Sanford Road
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23
Continue on Cottage Street
1.2 mi · 3 min · Cottage Street
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24
Turn left onto River Street
872 ft · 26 sec · River Street
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25
Continue on Washington Street
763 ft · 25 sec · Washington Street
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26
Turn left
27 m · 7 sec
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27
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Palermo and Sanford.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 295 South
Keep slight right to continue on I 295 South, ME 9, ME 126: Gardiner, Brunswick
50.5 mi · 00h 59m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Chance Rain Showers then Patchy Fog leaving Palermo and Partly Cloudy near Sanford.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Palermo to Sanford?
The road trip is about 110 miles (177.1 km) and usually takes 01h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Freeport is a useful midpoint, sitting about 53.8 miles from Palermo and 56.2 miles from Sanford.
How much longer is the road route than the straight-line distance?
The direct path is about 93.1 miles (149.8 km), while the road route adds roughly 16.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 2:36 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.31 one way or $30.61 round trip. Estimated CO2 is about 34.5 kg one way.
What should you check before leaving?
Before you leave, expect Chance Rain Showers then Patchy Fog around Palermo and Partly Cloudy near Sanford.
Stop Ideas Near Freeport
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Freeport.
Freeport
Brunswick Maine Street Station
Bath, Maine
Portland Transportation Center
Flight Path Map
This map shows the direct air route between Palermo and Sanford. Straight-line distance: 93.09 mi (149.81 km).
#1 Palermo
Town in Waldo County, Maine, United States of America
| Population | 1,525 |
| Coordinates | 44.4078500, -69.4739300 |
| Altitude | 111 |
| Country | United States |
#2 Sanford
City in York County, Maine, United States
| Population | 21,253 |
| Coordinates | 43.4392500, -70.7742200 |
| Altitude | 92 |
| Country | United States |
End: (-70.77414, 43.439348)
Estimated Travel Time
Distance: 177 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 40m |
| 40 mph (64.37 km/h) | 02h 45m |
| 50 mph (80.47 km/h) | 02h 12m |
| 60 mph (96.56 km/h) | 01h 50m |
| 70 mph (112.65 km/h) | 01h 34m |
| 80 mph (129 km/h) | 01h 22m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.95 | $15.31 | $30.61 |
| Mid-grade | $4.46 | $17.29 | $34.59 |
| Premium | $4.86 | $18.85 | $37.70 |
| Diesel | $6.00 | $23.27 | $46.54 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Maine · Apr 16, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.