How far is Muleshoe, TX from Frisco, TX?
The driving distance from Muleshoe, TX to Frisco, TX is about 401 miles (645.3 km), with a travel time of about 06h 12m by car.
- The straight-line flight distance is about 347.2 miles (558.8 km).
- For a round trip, plan for roughly 12h 24m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 12m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Texas, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Cloudy
Driving Route Map
The map below follows the saved road route between Muleshoe and Frisco.
Turn-by-Turn Driving Directions
Step-by-step road directions between Muleshoe and Frisco.
-
1
Start on North 1st Street
20 m · 7 sec · North 1st Street
-
2
Turn left onto East American Boulevard
17.8 mi · 18 min · East American Boulevard
-
3
Continue straight
8 mi · 8 min
-
4
Continue straight
35.3 mi · 36 min
-
5
Turn left onto FM 2641
5.4 mi · 9 min · FM 2641
-
6
Continue on Bluefield Street
1.2 km · 1 min · Bluefield Street
-
7
Continue on Regis Street
2.8 mi · 4 min · Regis Street
-
8
Continue on East Kent Street
1.3 km · 1 min · East Kent Street
-
9
Continue on East FM 2641
2 mi · 2 min · East FM 2641
-
10
At the end of the road, turn left
150 mi · 2 hr 39 min
-
11
Turn left onto North Main Street
3174 ft · 41 sec · North Main Street
-
12
Continue on US Highway 82
1.5 mi · 2 min · US Highway 82
-
13
Take the exit left toward US 82 East, US 183 North, US 277 North, US 283 North: Wichita Falls
48.1 mi · 54 min
-
14
Keep slight right to continue on US 82 East, US 281 South, US 287 South: Fort Worth
1.5 km · 2 min
-
15
Merge slight left onto Central East Freeway
1441 ft · 20 sec · Central East Freeway
-
16
Keep slight right to continue on Central East Freeway
1.8 mi · 2 min · Central East Freeway
-
17
Keep slight right to continue on Central East Freeway
69.8 mi · 1 hr 13 min · Central East Freeway
-
18
Take the exit slight right
764 ft · 21 sec
-
19
Keep slight left
45 m · 4 sec
-
20
Turn left onto West US Highway 380
21.8 mi · 25 min · West US Highway 380
-
21
Continue on West University Drive
3.3 mi · 4 min · West University Drive
-
22
Take the exit slight right
88 m · 8 sec
-
23
Turn straight onto North Interstate 35
599 ft · 12 sec · North Interstate 35
-
24
Take the ramp slight left toward I 35 South
753 ft · 18 sec
-
25
Merge slight left
1.6 km · 1 min
-
26
Continue on I 35E South: Dallas
8.3 mi · 9 min
-
27
Take the exit slight right toward FM 2181: Swisher Road
939 ft · 27 sec
-
28
Turn straight onto South Interstate 35E
1 mi · 2 min · South Interstate 35E
-
29
Turn left onto West Swisher Road
1.1 mi · 2 min · West Swisher Road
-
30
Continue on Lewisville Lake Toll Bridge
2.1 mi · 3 min · Lewisville Lake Toll Bridge
-
31
Continue on West Eldorado Parkway
3.8 mi · 7 min · West Eldorado Parkway
-
32
Continue on East Eldorado Parkway
2.7 mi · 5 min · East Eldorado Parkway
-
33
Turn right onto Witt Road
1.6 km · 2 min · Witt Road
-
34
Turn left onto King Road
2713 ft · 1 min · King Road
-
35
Continue on Main Street
3.9 mi · 8 min · Main Street
-
36
Turn left onto 5th Street
121 m · 21 sec · 5th Street
-
37
Turn right onto Oak Street
109 m · 18 sec · Oak Street
-
38
Turn right onto 6th Street
108 m · 18 sec · 6th Street
-
39
Turn right onto Main Street
82 m · 8 sec · Main Street
-
40
Arrive at your destination
0 m · 1 sec · Main Street
Car Route Details
A richer read on the saved driving route between Muleshoe and Frisco.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Longest stretch
At the end of the road, turn left
150 mi · 02h 39m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Muleshoe and Mostly Cloudy near Frisco.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Muleshoe to Frisco?
The road trip is about 401 miles (645.3 km) and usually takes 06h 12m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Benjamin is a useful midpoint, sitting about 198.5 miles from Muleshoe and 202.4 miles from Frisco.
How much longer is the road route than the straight-line distance?
The direct path is about 347.2 miles (558.8 km), while the road route adds roughly 53.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $53.47 one way or $106.95 round trip. Estimated CO2 is about 125.8 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Muleshoe and Mostly Cloudy near Frisco.
Stop Ideas Near Benjamin
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Munday City Hall
Benjamin City Office
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Benjamin.
Flight Path Map
This map shows the direct air route between Muleshoe and Frisco. Straight-line distance: 347.2 mi (558.76 km).
#1 Muleshoe
City in Texas, USA
| Population | 4,822 |
| Coordinates | 34.2264700, -102.7238300 |
| Altitude | 1156 |
| Country | United States |
#2 Frisco
Frisco is a city in the US state of Texas located in the counties of Collin and Denton, and an affluent and rapidly developing suburb of Dallas.
| Population | 209,980 |
| Coordinates | 33.1506700, -96.8236100 |
| Altitude | 212 |
| Country | United States |
End: Main Street (-96.823654, 33.150495)
Estimated Travel Time
Distance: 645 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 21m |
| 40 mph (64.37 km/h) | 10h 01m |
| 50 mph (80.47 km/h) | 08h 01m |
| 60 mph (96.56 km/h) | 06h 40m |
| 70 mph (112.65 km/h) | 05h 43m |
| 80 mph (129 km/h) | 05h 00m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $53.47 | $106.95 |
| Mid-grade | $4.25 | $60.17 | $120.33 |
| Premium | $4.59 | $64.96 | $129.93 |
| Diesel | $3.99 | $56.50 | $113.00 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.