How far is Muleshoe, TX from Laredo, TX?
The driving distance from Muleshoe, TX to Laredo, TX is about 595.1 miles (957.7 km), with a travel time of about 09h 10m by car.
- The straight-line flight distance is about 501.9 miles (807.7 km).
- For a round trip, plan for roughly 18h 21m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 09h 10m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Menard County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Muleshoe and Laredo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Muleshoe and Laredo.
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1
Start on North 1st Street
20 m · 7 sec · North 1st Street
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2
Turn left onto East American Boulevard
17.8 mi · 18 min · East American Boulevard
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3
Continue straight
8 mi · 8 min
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4
Continue straight
42 mi · 44 min
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5
Merge slight left onto Avenue Q
4 mi · 5 min · Avenue Q
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6
Continue on Slaton Road
4.8 mi · 6 min · Slaton Road
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7
Continue on East Highway 84
6.9 mi · 7 min · East Highway 84
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8
Continue on Trooper Jerry Don Davis Memorial Highway
4.5 mi · 5 min · Trooper Jerry Don Davis Memorial Highway
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9
Continue on East Highway 84
20 mi · 20 min · East Highway 84
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10
Continue on North US Highway 84
1 mi · 1 min · North US Highway 84
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11
Turn left onto East 15th Street
734 ft · 17 sec · East 15th Street
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12
Turn right onto Ralls Road
1863 ft · 38 sec · Ralls Road
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13
Turn straight onto North Avenue F
1.1 mi · 2 min · North Avenue F
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14
At the end of the road, turn left onto US Highway 84
73.9 mi · 1 hr 14 min · US Highway 84
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15
Keep slight left to continue on I 20 East, US 84 East: Abilene
6.5 mi · 7 min
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16
Take the exit slight right toward SH 70 South, SH 70 Business: Sweetwater, San Angelo
737 ft · 18 sec
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17
Turn slight left onto Southwest Georgia Avenue
624 ft · 17 sec · Southwest Georgia Avenue
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18
Turn right onto Lamar Street
1.2 km · 1 min · Lamar Street
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19
Continue on State Highway 70
10.4 mi · 11 min · State Highway 70
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20
Turn left onto State Highway 153
29.5 mi · 33 min · State Highway 153
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21
Turn right
12.3 mi · 13 min
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22
Turn left
6.3 mi · 7 min
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23
At the end of the road, turn right onto Hutchings Avenue
118 m · 18 sec · Hutchings Avenue
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24
Turn left onto South 7th Street
16.5 mi · 18 min · South 7th Street
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25
Continue on Grassmeyer Street
41.9 mi · 45 min · Grassmeyer Street
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26
Continue on Ellis Street
29.4 mi · 31 min · Ellis Street
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27
Take the exit left toward I 10 East: San Antonio
40 mi · 38 min
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28
Continue straight
54.3 mi · 55 min
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29
Keep slight right
5.4 mi · 6 min
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30
Take the exit slight right toward Frontage Road
3038 ft · 1 min
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31
Turn straight onto Interstate 10 West
2224 ft · 41 sec · Interstate 10 West
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32
Turn right onto North Loop 1604 West
3234 ft · 1 min · North Loop 1604 West
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33
Take the ramp slight left toward Loop 1604 West
1157 ft · 28 sec
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34
Merge slight left onto Anderson Loop
24.4 mi · 29 min · Anderson Loop
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35
Turn right onto Interstate 35 South
940 ft · 20 sec · Interstate 35 South
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36
Take the ramp slight left toward I 35 South
1153 ft · 28 sec
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37
Merge slight left onto Purple Heart Trail
139.7 mi · 2 hr 21 min · Purple Heart Trail
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38
Turn right onto Houston Street
1607 ft · 42 sec · Houston Street
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39
Turn left onto Salinas Avenue
83 m · 12 sec · Salinas Avenue
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40
Turn left onto Matamoros Street
93 m · 5 sec · Matamoros Street
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41
Arrive at your destination
0 m · 1 sec · Matamoros Street
Car Route Details
A richer read on the saved driving route between Muleshoe and Laredo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Purple Heart Trail
Merge slight left onto Purple Heart Trail
140 mi · 02h 21m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Muleshoe and Mostly Sunny near Laredo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Muleshoe to Laredo?
The road trip is about 595.1 miles (957.7 km) and usually takes 09h 10m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Menard is a useful midpoint, sitting about 302.7 miles from Muleshoe and 292.4 miles from Laredo.
How much longer is the road route than the straight-line distance?
The direct path is about 501.9 miles (807.7 km), while the road route adds roughly 93.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $79.36 one way or $158.72 round trip. Estimated CO2 is about 186.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Muleshoe and Mostly Sunny near Laredo.
Stop Ideas Near Menard
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Menard City Hall
Eden City Hall
Eden Housing Authority
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Menard.
Flight Path Map
This map shows the direct air route between Muleshoe and Laredo. Straight-line distance: 501.88 mi (807.69 km).
#1 Muleshoe
City in Texas, USA
| Population | 4,822 |
| Coordinates | 34.2264700, -102.7238300 |
| Altitude | 1156 |
| Country | United States |
#2 Laredo
The third most populous city in Texas and the center of the Laredo metropolitan area.
| Population | 263,640 |
| Coordinates | 27.5064100, -99.5075400 |
| Altitude | 126 |
| Country | United States |
End: Matamoros Street (-99.507507, 27.506385)
Estimated Travel Time
Distance: 958 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 19h 49m |
| 40 mph (64.37 km/h) | 14h 52m |
| 50 mph (80.47 km/h) | 11h 54m |
| 60 mph (96.56 km/h) | 09h 55m |
| 70 mph (112.65 km/h) | 08h 30m |
| 80 mph (129 km/h) | 07h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $79.36 | $158.72 |
| Mid-grade | $4.25 | $89.29 | $178.58 |
| Premium | $4.59 | $96.41 | $192.82 |
| Diesel | $3.99 | $83.85 | $167.71 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.