How far is Key Largo, FL from Clearwater, FL?

The driving distance from Key Largo, FL to Clearwater, FL is about 330.3 miles (531.6 km), with a travel time of about 05h 16m by car.

  • The straight-line flight distance is about 246.4 miles (396.6 km).
  • For a round trip, plan for roughly 10h 33m of driving time before adding stops, traffic, or weather delays.
  • A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Trip Tools

Reverse, save, or send this route

This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.

Reverse Route
Quick Snapshot
Road
330.32 mi
05h 16m
Flight
246.42 mi
396.58 km direct

This drive is better planned with a longer stop or an overnight stay.

Learn Distance

Choose another destination from Key Largo.

Flight Distance

Direct air line
246.42 mi
Kilometers
396.58 km
Flight Time
00h 29m

Driving Distance

Road route
330.32 mi
Kilometers
531.6 km
Drive Time
05h 16m

Gas Cost Calculator

Leave and Arrive Planner

Pick a departure time to see your estimated arrival and same-day return window.

Drive time stays fixed at 05h 16m.

Arrival Snapshot
Arrive in Clearwater
Thu, Apr 23, 4:07 AM EDT
Return by in Key Largo
Thu, Apr 23, 9:24 AM EDT
Useful when you're deciding between a quick errand, a day trip, or a longer stop.
Leave Key Largo
2026-04-22T22:50
Arrive Clearwater
Thu, Apr 23, 4:07 AM EDT
Route Timing
05h 16m
One way by road
Best Departure Window
6:00 AM to 8:00 AM EDT
Leave early for more breathing room
Arrive between
11:17 AM to 1:17 PM EDT

An early departure helps you fit a real stop into the day without turning the return into a late-night drive.

Leave by
6:26 AM EDT
Keeps a same-day return open with about 04h 00m at the destination.
Back in Key Largo
9:00 PM EDT
Early departure recommended

You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.

Halfway Point

A useful midpoint for breaks, coffee, or meeting in the middle.

Mid-route stop
Golden Gate
FL

Census designated place

From Key Largo
164.3 mi
02h 38m
To Clearwater
166 mi
02h 38m

Route Weather Snapshot

Check the forecast at both ends before you head out.

Origin
80°F
Wednesday

Mostly Sunny

Starts
Wed, Apr 22 6:00 AM EDT
Wind
15 to 20 mph E
Destination
81°F
Wednesday

Partly Sunny

Starts
Wed, Apr 22 6:00 AM EDT
Wind
7 to 10 mph ENE

Driving Route Map

The map below follows the saved road route between Key Largo and Clearwater.

Turn-by-Turn Driving Directions

Step-by-step road directions between Key Largo and Clearwater.

  1. 1

    Start on Harbor Drive

    94 m · 16 sec · Harbor Drive

  2. 2

    Turn right onto Overseas Highway

    9.3 mi · 16 min · Overseas Highway

  3. 3

    Continue on Dixie Highway

    19.4 mi · 27 min · Dixie Highway

  4. 4

    Take the exit slight right toward Miami, Orlando, Florida's Turnpike North

    1785 ft · 38 sec

  5. 5

    Continue on Homestead Extension of Florida's Turnpike

    13.2 mi · 16 min · Homestead Extension of Florida's Turnpike

  6. 6

    Keep slight right to continue on Homestead Extension of Florida's Turnpike

    3.6 mi · 5 min · Homestead Extension of Florida's Turnpike

  7. 7

    Keep slight left to continue on Homestead Extension of Florida's Turnpike

    2.5 mi · 3 min · Homestead Extension of Florida's Turnpike

  8. 8

    Keep slight right to continue on Homestead Extension of Florida's Turnpike

    15.5 mi · 18 min · Homestead Extension of Florida's Turnpike

  9. 9

    Take the exit slight right toward US 27: Okeechobee Road

    1140 ft · 28 sec

  10. 10

    Keep slight right to continue on US 27: Okeechobee Road

    633 ft · 16 sec

  11. 11

    Merge slight left onto Okeechobee Road

    17.6 mi · 23 min · Okeechobee Road

  12. 12

    Take the exit slight right toward I 75: Miami, Fort Lauderdale, Naples

    1360 ft · 33 sec

  13. 13

    Keep slight left to continue on I 75 North: Naples

    1.3 km · 2 min

  14. 14

    Merge slight left onto Alligator Alley

    203.5 mi · 3 hr 38 min · Alligator Alley

  15. 15

    Take the exit slight right toward I 275 North: Saint Petersburg

    5.7 mi · 8 min

  16. 16

    Keep slight left

    1610 ft · 20 sec

  17. 17

    Merge slight right onto Sunshine Skyway Bridge

    19.5 mi · 23 min · Sunshine Skyway Bridge

  18. 18

    Take the exit slight right toward 54th Avenue North Westbound

    1483 ft · 36 sec

  19. 19

    Turn straight onto 54th Avenue North

    1.5 km · 2 min · 54th Avenue North

  20. 20

    Turn right onto 34th Street North

    2972 ft · 1 min · 34th Street North

  21. 21

    Continue on US Highway 19 North

    9.1 mi · 13 min · US Highway 19 North

  22. 22

    Take the exit slight right toward FL 60: Seville Boulevard, Gulf To Bay

    556 ft · 14 sec

  23. 23

    Continue on US 19 Northbound Frontage Road

    2125 ft · 54 sec · US 19 Northbound Frontage Road

  24. 24

    Continue on Northbound Frontage Road

    1034 ft · 25 sec · Northbound Frontage Road

  25. 25

    Take the exit slight left

    635 ft · 20 sec

  26. 26

    Continue on Gulf to Bay Boulevard

    2.7 mi · 5 min · Gulf to Bay Boulevard

  27. 27

    Continue on Court Street

    1.5 mi · 3 min · Court Street

  28. 28

    Turn right onto South Ft Harrison Avenue

    1297 ft · 40 sec · South Ft Harrison Avenue

  29. 29

    Arrive at your destination

    0 m · 1 sec · North Fort Harrison Avenue

Car Route Details

A richer read on the saved driving route between Key Largo and Clearwater.

OSRM road route
Drive Character

Long-distance drive

This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.

Directions
29 steps
9 turns on the saved route
Ramps & Exits
10
3 merges, 7 ramps or exits
Navigation Density
8.8 / 100 mi
Decision points by distance
Main Roads
Alligator Alley
203 mi · 62%
Homestead Extension of Florida's Turnpike
34.8 mi · 11%
Sunshine Skyway Bridge
19.5 mi · 6%
Dixie Highway
19.4 mi · 6%
Okeechobee Road
17.6 mi · 5%
Overseas Highway
9.29 mi · 3%
Longest Stretch

Alligator Alley

Merge slight left onto Alligator Alley

203 mi · 03h 38m

Route Summary

A quick read on whether this route feels easy, ambitious, or worth planning around.

Trip Read

A longer out-and-back drive

This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.

Drive Time
05h 16m
Long day trip
Same-Day Return
10h 34m
Round-trip wheel time
Road vs Air
+83.9 mi
246.4 mi direct line
Halfway Stop
Golden Gate
02h 38m from Key Largo
Leave By
6:26 AM EDT
Early departure recommended
Weather Watch

Mostly Sunny leaving Key Largo and Partly Sunny near Clearwater.

Trip Questions

Direct answers travelers usually want before committing to the drive.

How long does it take to drive from Key Largo to Clearwater?

The road trip is about 330.3 miles (531.6 km) and usually takes 05h 16m in normal driving conditions.

Is this a same-day trip or an overnight route?

This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.

What is the halfway point on this route?

Golden Gate is a useful midpoint, sitting about 164.3 miles from Key Largo and 166 miles from Clearwater.

How much longer is the road route than the straight-line distance?

The direct path is about 246.4 miles (396.6 km), while the road route adds roughly 83.9 extra miles because roads do not follow the straight air line.

When is the best time to leave for this route?

A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:26 AM EDT.

How much will gas cost for this route?

Using about 28.3 MPG, regular gas is estimated at $48.37 one way or $96.73 round trip. Estimated CO2 is about 103.6 kg one way.

What should you check before leaving?

Before you leave, expect Mostly Sunny around Key Largo and Partly Sunny near Clearwater.

Stop Ideas Near Golden Gate

Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.

Mid-route Guidance
Local place coverage is thin around Golden Gate, so nearby transit and meeting points are shown instead.
Reviewed stop coverage is still thin around this midpoint, so practical transit waypoints are shown on the right.

Transit and Meeting Points

Useful pickup, handoff, or rendezvous points close to Golden Gate.

BUS

Fort Myers, Florida

58 mi away
6050 Plaza Drive
BUS

Port Charlotte, Florida

98 mi away
909 King Highway

Flight Path Map

This map shows the direct air route between Key Largo and Clearwater. Straight-line distance: 246.42 mi (396.58 km).

Key Largo

#1 Key Largo

Census designated place in Florida, United States

Population10,433
Coordinates25.0865200, -80.4472800
Altitude2
CountryUnited States
Clearwater

#2 Clearwater

The second most populous city in Pinellas County, Florida.

Population116,552
Coordinates27.9658500, -82.8001000
Altitude9
CountryUnited States
Start: Harbor Drive (-80.44767, 25.086521)
End: North Fort Harrison Avenue (-82.799962, 27.965851)

Estimated Travel Time

Distance: 532 km by road

SpeedTime
30 mph (48.3 km/h)11h 00m
40 mph (64.37 km/h)08h 15m
50 mph (80.47 km/h)06h 36m
60 mph (96.56 km/h)05h 30m
70 mph (112.65 km/h)04h 43m
80 mph (129 km/h)04h 07m

Fuel, Round Trip and CO2

Estimated fuel cost and emissions for this route.

One-way fuel
11.66 gal
44.12 L · about $48.37
Round trip
$96.73
23.32 gal · 88.24 L
Estimated CO2
103.6 kg one way
Round trip: 207.2 kg / 457 lb CO2, using regular gasoline.
Fuel$/galOne wayRound trip
Regular gas $4.15 $48.37 $96.73
Mid-grade $4.60 $53.59 $107.18
Premium $4.90 $57.09 $114.17
Diesel $4.35 $50.72 $101.44

Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.

Prices in Florida · Apr 23, 2026

There is no time difference between Key Largo and Clearwater. The current time is 22:50:48.

Distance to Other Cities

Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.

How did we calculate? Place names are translated into coordinates. The Haversine formula calculates straight-line distance; driving distance uses road network data.