How far is De Soto, MO from St. Louis, MO?
The driving distance from De Soto, MO to St. Louis, MO is about 47.1 miles (75.8 km), with a travel time of about 00h 50m by car.
- The straight-line flight distance is about 38.8 miles (62.5 km).
- For a round trip, plan for roughly 01h 40m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 00h 50m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census designated place
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Scattered Rain Showers
Driving Route Map
The map below follows the saved road route between De Soto and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between De Soto and St. Louis.
-
1
Start on Easton Street
133 m · 24 sec · Easton Street
-
2
At the end of the road, turn left onto North Main Street
1 km · 57 sec · North Main Street
-
3
Turn right onto Fountain City Road
1.2 km · 2 min · Fountain City Road
-
4
Turn right
4.2 mi · 5 min
-
5
Take the ramp left toward US 67 North: Festus, Crystal City
1377 ft · 18 sec
-
6
Merge slight left
5.7 mi · 7 min
-
7
Keep slight right
1750 ft · 27 sec
-
8
Take the exit straight toward I 55 North: Saint Louis
1735 ft · 49 sec
-
9
Merge slight left
20.5 mi · 22 min
-
10
Continue on Rosa Parks Highway
12.5 mi · 16 min · Rosa Parks Highway
-
11
Take the exit slight right toward MO 30 East: Gravois Avenue
1001 ft · 24 sec
-
12
Turn slight right onto Gravois Avenue
1044 ft · 27 sec · Gravois Avenue
-
13
Continue on South Tucker Boulevard
1.3 mi · 3 min · South Tucker Boulevard
-
14
Turn right onto Market Street
26 m · 2 sec · Market Street
-
15
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between De Soto and St. Louis.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Merge slight left
20.5 mi · 00h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Chance Showers And Thunderstorms leaving De Soto and Scattered Rain Showers near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from De Soto to St. Louis?
The road trip is about 47.1 miles (75.8 km) and usually takes 00h 50m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Barnhart is a useful midpoint, sitting about 23.5 miles from De Soto and 23.5 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 38.8 miles (62.5 km), while the road route adds roughly 8.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 4:50 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $6.26 one way or $12.52 round trip. Estimated CO2 is about 14.8 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around De Soto and Scattered Rain Showers near St. Louis.
Stop Ideas Near Barnhart
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Barnhart.
Kirkwood
Gateway Transportation Center
Washington
Alton
Flight Path Map
This map shows the direct air route between De Soto and St. Louis. Straight-line distance: 38.86 mi (62.54 km).
#1 De Soto
City in Jefferson County, Missouri
| Population | 6,340 |
| Coordinates | 38.1395000, -90.5551300 |
| Altitude | 160 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 76 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 01h 34m |
| 40 mph (64.37 km/h) | 01h 10m |
| 50 mph (80.47 km/h) | 00h 56m |
| 60 mph (96.56 km/h) | 00h 47m |
| 70 mph (112.65 km/h) | 00h 40m |
| 80 mph (129 km/h) | 00h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $6.26 | $12.52 |
| Mid-grade | $4.25 | $7.06 | $14.12 |
| Premium | $4.65 | $7.73 | $15.45 |
| Diesel | $5.30 | $8.80 | $17.61 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 31, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.