How far is Waynesville, MO from Cape Girardeau, MO?
The driving distance from Waynesville, MO to Cape Girardeau, MO is about 197.7 miles (318.1 km), with a travel time of about 03h 34m by car.
- The straight-line flight distance is about 151.3 miles (243.5 km).
- For a round trip, plan for roughly 07h 09m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 34m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Jefferson County, Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Waynesville and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Waynesville and Cape Girardeau.
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1
Start on the route
2.1 mi · 4 min
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2
Turn left onto I 44 East: Rolla
652 ft · 16 sec
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3
Merge slight left
78.6 mi · 1 hr 25 min
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4
Take the exit slight right toward MO WW, MO AB, MO 30: Saint Clair
895 ft · 23 sec
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5
Turn right
728 ft · 22 sec
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6
Continue on West Gravois Avenue
1012 ft · 25 sec · West Gravois Avenue
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7
Take the exit slight right toward MO 30, MO 47
58 m · 5 sec
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8
Merge slight left onto East Gravois Avenue
27 mi · 38 min · East Gravois Avenue
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9
Turn right
11.6 mi · 17 min
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10
Take the exit slight right
55 m · 5 sec
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11
Turn right onto Metropolitan Boulevard
641 ft · 15 sec · Metropolitan Boulevard
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12
Enter the roundabout and take exit 3 toward I 55 South: Cape Girardeau
66 m · 10 sec
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13
Exit the roundabout onto I 55 South: Cape Girardeau
832 ft · 10 sec
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14
Merge slight left onto Jeff McBride Memorial Highway
84.8 mi · 1 hr 31 min · Jeff McBride Memorial Highway
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15
Take the exit slight right toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
814 ft · 17 sec
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16
Keep slight left to continue on I 55 Business, US 61 South, MO 34 East: Cape Girardeau
1354 ft · 29 sec
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17
Continue on North Kingshighway
3.6 mi · 6 min · North Kingshighway
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18
Turn left onto Broadway Street
2 mi · 4 min · Broadway Street
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19
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Waynesville and Cape Girardeau.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Jeff McBride Memorial Highway
Merge slight left onto Jeff McBride Memorial Highway
84.8 mi · 01h 31m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving Waynesville and Chance Rain Showers near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Waynesville to Cape Girardeau?
The road trip is about 197.7 miles (318.1 km) and usually takes 03h 34m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Scotsdale is a useful midpoint, sitting about 105.5 miles from Waynesville and 92.1 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 151.3 miles (243.5 km), while the road route adds roughly 46.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:50 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $26.28 one way or $52.57 round trip. Estimated CO2 is about 61.9 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around Waynesville and Chance Rain Showers near Cape Girardeau.
Stop Ideas Near Scotsdale
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Scotsdale.
Kirkwood
Washington
Gateway Transportation Center
Alton
Flight Path Map
This map shows the direct air route between Waynesville and Cape Girardeau. Straight-line distance: 151.29 mi (243.47 km).
#1 Waynesville
City in Pulaski County, Missouri, United States
| Population | 5,308 |
| Coordinates | 37.8286500, -92.2007200 |
| Altitude | 246 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 318 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 35m |
| 40 mph (64.37 km/h) | 04h 56m |
| 50 mph (80.47 km/h) | 03h 57m |
| 60 mph (96.56 km/h) | 03h 17m |
| 70 mph (112.65 km/h) | 02h 49m |
| 80 mph (129 km/h) | 02h 27m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $26.28 | $52.57 |
| Mid-grade | $4.25 | $29.64 | $59.29 |
| Premium | $4.65 | $32.44 | $64.88 |
| Diesel | $5.30 | $36.97 | $73.94 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 30, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.