How far is Tallahassee, FL from San Antonio, FL?
The driving distance from Tallahassee, FL to San Antonio, FL is about 245.8 miles (395.5 km), with a travel time of about 04h 37m by car.
- The straight-line flight distance is about 188.9 miles (304 km).
- For a round trip, plan for roughly 09h 14m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 37m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Alachua County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Tallahassee and San Antonio.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tallahassee and San Antonio.
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1
Start on South Monroe Street
55 m · 8 sec · South Monroe Street
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2
Turn right onto East Pensacola Street
1428 ft · 47 sec · East Pensacola Street
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3
Turn left onto South Franklin Boulevard
2557 ft · 1 min · South Franklin Boulevard
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4
Turn right onto East Tennessee Street
3230 ft · 1 min · East Tennessee Street
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5
Continue on Mahan Drive
6.5 mi · 12 min · Mahan Drive
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6
Take the ramp slight right toward I 10 East: Lake City
1.1 km · 1 min
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7
Merge slight left
86.9 mi · 1 hr 33 min
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8
Take the exit slight right toward I-75 South: Tampa
1959 ft · 37 sec
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9
Merge slight left
141.8 mi · 2 hr 32 min
-
10
Take the exit slight right toward CR 41: Dade City
674 ft · 23 sec
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11
Keep slight right
78 m · 6 sec
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12
Turn straight onto Blanton Road
1.6 mi · 2 min · Blanton Road
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13
Turn right onto James Road
1310 ft · 43 sec · James Road
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14
Turn left onto Jessamine Road
3 mi · 5 min · Jessamine Road
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15
Continue on Curley Road
2.2 mi · 4 min · Curley Road
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16
Continue on Curley Street
1.2 km · 2 min · Curley Street
-
17
Turn right onto Pennsylvania Avenue
19 m · 3 sec · Pennsylvania Avenue
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18
Arrive at your destination
0 m · 1 sec · Pennsylvania Avenue
Car Route Details
A richer read on the saved driving route between Tallahassee and San Antonio.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I-75 South
Merge slight left
142 mi · 02h 32m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Tallahassee and Sunny near San Antonio.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tallahassee to San Antonio?
The road trip is about 245.8 miles (395.5 km) and usually takes 04h 37m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
High Springs is a useful midpoint, sitting about 123 miles from Tallahassee and 122.8 miles from San Antonio.
How much longer is the road route than the straight-line distance?
The direct path is about 188.9 miles (304 km), while the road route adds roughly 56.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:46 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.96 one way or $71.93 round trip. Estimated CO2 is about 77.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Tallahassee and Sunny near San Antonio.
Stop Ideas Near High Springs
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to High Springs.
Gainesville, Florida
Waldo, Florida
Ocala, Florida
Palatka
Flight Path Map
This map shows the direct air route between Tallahassee and San Antonio. Straight-line distance: 188.89 mi (303.99 km).
#1 Tallahassee
The capital of Florida.
| Population | 196,326 |
| Coordinates | 30.4382600, -84.2807300 |
| Altitude | 62 |
| Country | United States |
#2 San Antonio
City in Pasco County, Florida, USA
| Population | 1,506 |
| Coordinates | 28.3361100, -82.2745300 |
| Altitude | 51 |
| Country | United States |
End: San Antonio (-82.27453, 28.33611)
Estimated Travel Time
Distance: 395 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 11m |
| 40 mph (64.37 km/h) | 06h 08m |
| 50 mph (80.47 km/h) | 04h 54m |
| 60 mph (96.56 km/h) | 04h 05m |
| 70 mph (112.65 km/h) | 03h 30m |
| 80 mph (129 km/h) | 03h 03m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $35.96 | $71.93 |
| Mid-grade | $4.60 | $39.85 | $79.69 |
| Premium | $4.90 | $42.45 | $84.90 |
| Diesel | $4.35 | $37.71 | $75.43 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.