How far is Santa Fe, TX from Brownsville, TX?
The driving distance from Santa Fe, TX to Brownsville, TX is about 367.4 miles (591.3 km), with a travel time of about 07h 09m by car.
- The straight-line flight distance is about 281.2 miles (452.6 km).
- For a round trip, plan for roughly 14h 19m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 09m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Frederick County Maryland
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Santa Fe and Brownsville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Santa Fe and Brownsville.
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1
Start on Highway 6
3.3 mi · 5 min · Highway 6
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2
Continue on East State Highway 6
16.9 mi · 25 min · East State Highway 6
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3
Continue on Alvin-Sugarland Road
4.4 mi · 7 min · Alvin-Sugarland Road
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4
Continue straight
891 ft · 17 sec
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5
Continue straight
2.5 mi · 4 min
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6
Continue straight
7.9 mi · 13 min
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7
Turn left onto Southwest Freeway Frontage Road
2972 ft · 51 sec · Southwest Freeway Frontage Road
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8
Take the ramp slight left toward US 59 South, I 69 South
1146 ft · 15 sec
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9
Merge slight left onto Southwest Freeway
14 mi · 15 min · Southwest Freeway
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10
Take the exit slight right toward Spur 10: Cottonwood, Church Road, Hartledge Road
1158 ft · 28 sec
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11
Turn straight onto Southwest Freeway Frontage Road
1.5 km · 2 min · Southwest Freeway Frontage Road
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12
Continue on Southwest Freeway Frontage Road
2217 ft · 1 min · Southwest Freeway Frontage Road
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13
Continue on US 59 Southbound Frontage Road
1.4 km · 2 min · US 59 Southbound Frontage Road
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14
Take the ramp straight
1027 ft · 25 sec
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15
Merge slight left
9.2 mi · 11 min
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16
Keep slight left
6.6 mi · 8 min
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17
Take the exit slight right
1.5 mi · 2 min
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18
Continue on US Highway 59
74.7 mi · 1 hr 22 min · US Highway 59
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19
Keep slight left to continue on Spur 91
1.6 km · 1 min · Spur 91
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20
Merge slight right onto US Highway 77 South
33.2 mi · 38 min · US Highway 77 South
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21
Turn straight onto Alamo Street
37.1 mi · 43 min · Alamo Street
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22
Take the exit straight toward I 37, US 77, I 69E
538 ft · 13 sec
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23
Keep slight left
1965 ft · 48 sec
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24
Merge slight right
2.5 mi · 2 min
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25
Take the exit slight right toward I 69E, US 77: Kingsville, Brownsville
31.3 mi · 34 min
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26
Keep slight left to continue on U.S. Highway 77
61.3 mi · 1 hr 9 min · U.S. Highway 77
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27
Keep slight left to continue on U.S. Highway 77
43.7 mi · 47 min · U.S. Highway 77
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28
Continue on North Expressway
2.1 mi · 2 min · North Expressway
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29
Keep slight left to continue on North Expressway
9 mi · 10 min · North Expressway
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30
Take the exit slight right toward 12th-14th Street
1730 ft · 42 sec
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31
Turn straight onto South Expressway
101 m · 9 sec · South Expressway
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32
Turn right onto East 12th Street
1.2 km · 2 min · East 12th Street
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33
Turn right onto East Washington Street
9 m · 1 sec · East Washington Street
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34
Arrive at your destination
0 m · 1 sec · East Washington Street
Car Route Details
A richer read on the saved driving route between Santa Fe and Brownsville.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
US Highway 59
Continue on US Highway 59
74.7 mi · 01h 22m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Showers And Thunderstorms leaving Santa Fe and Mostly Sunny near Brownsville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Santa Fe to Brownsville?
The road trip is about 367.4 miles (591.3 km) and usually takes 07h 09m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Woodsboro is a useful midpoint, sitting about 184 miles from Santa Fe and 183.5 miles from Brownsville.
How much longer is the road route than the straight-line distance?
The direct path is about 281.2 miles (452.6 km), while the road route adds roughly 86.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $49.01 one way or $98.03 round trip. Estimated CO2 is about 115.3 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Santa Fe and Mostly Sunny near Brownsville.
Flight Path Map
This map shows the direct air route between Santa Fe and Brownsville. Straight-line distance: 281.26 mi (452.65 km).
#1 Santa Fe
City in Galveston County, Texas, United States
| Population | 13,461 |
| Coordinates | 29.3780100, -95.1057600 |
| Altitude | 9 |
| Country | United States |
#2 Brownsville
The southernmost city in Texas.
| Population | 183,428 |
| Coordinates | 25.9017500, -97.4974800 |
| Altitude | 10 |
| Country | United States |
End: Brownsville (-97.49748, 25.90175)
Estimated Travel Time
Distance: 591 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 14m |
| 40 mph (64.37 km/h) | 09h 11m |
| 50 mph (80.47 km/h) | 07h 20m |
| 60 mph (96.56 km/h) | 06h 07m |
| 70 mph (112.65 km/h) | 05h 14m |
| 80 mph (129 km/h) | 04h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $49.01 | $98.03 |
| Mid-grade | $4.25 | $55.15 | $110.30 |
| Premium | $4.59 | $59.55 | $119.09 |
| Diesel | $3.99 | $51.79 | $103.58 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.