How far is Brownsville, TX from Santa Fe, TX?
The driving distance from Brownsville, TX to Santa Fe, TX is about 368.7 miles (593.3 km), with a travel time of about 07h 30m by car.
- The straight-line flight distance is about 281.2 miles (452.6 km).
- For a round trip, plan for roughly 15h 01m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 30m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Frederick County Maryland
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between Brownsville and Santa Fe.
Turn-by-Turn Driving Directions
Step-by-step road directions between Brownsville and Santa Fe.
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1
Start on East Washington Street
1682 ft · 41 sec · East Washington Street
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2
Turn right onto East 7th Street
1.5 km · 2 min · East 7th Street
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3
Turn left onto North Frontage Road
999 ft · 20 sec · North Frontage Road
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4
Take the ramp slight left toward I 69E North, US 77 North, US 83 North
2235 ft · 55 sec
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5
Merge slight left onto North Expressway
10.6 mi · 12 min · North Expressway
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6
Continue on U.S. Highway 77
102 mi · 1 hr 53 min · U.S. Highway 77
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7
Keep slight left
1157 ft · 14 sec
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8
Merge slight right
1.2 mi · 1 min
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9
Continue on U.S. Highway 77
11.6 mi · 13 min · U.S. Highway 77
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10
Take the exit slight right
1410 ft · 34 sec
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11
Turn straight onto US Highway 77 Frontage Road
148 m · 18 sec · US Highway 77 Frontage Road
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12
Turn right onto County Road 10
1 mi · 4 min · County Road 10
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13
Turn left onto County Road 79
4 mi · 16 min · County Road 79
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14
Turn left onto County Road 18
848 ft · 44 sec · County Road 18
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15
Turn sharp right
1.1 mi · 3 min
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16
Take the ramp straight
2351 ft · 57 sec
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17
Merge slight left onto Driscoll Bypass
2.3 mi · 2 min · Driscoll Bypass
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18
Continue on U.S. Highway 77
13.2 mi · 14 min · U.S. Highway 77
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19
Merge slight left
1.4 mi · 1 min
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20
Keep slight left
1.3 km · 50 sec
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21
Continue straight
141 m · 5 sec
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22
Take the exit slight right toward Sinton, Victoria
37.6 mi · 44 min
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23
Turn slight right onto United States Highway 77
33 mi · 37 min · United States Highway 77
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24
Keep slight left to continue on Spur 91
1.5 mi · 2 min · Spur 91
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25
Merge slight left onto US Highway 59 South
88.6 mi · 1 hr 38 min · US Highway 59 South
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26
Take the exit slight right
1551 ft · 38 sec
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27
Continue on 59 Northbound Frontage Road
1.6 mi · 2 min · 59 Northbound Frontage Road
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28
Continue straight
2146 ft · 59 sec
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29
Continue on US 59 Northbound Frontage Road
2 mi · 5 min · US 59 Northbound Frontage Road
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30
Continue on Southwest Freeway Frontage Road
1.3 mi · 3 min · Southwest Freeway Frontage Road
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31
Take the ramp slight left toward I 69 North, US 59 North
1304 ft · 32 sec
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32
Merge slight left onto Southwest Freeway
13.9 mi · 15 min · Southwest Freeway
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33
Take the exit slight right
1047 ft · 18 sec
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34
Turn straight onto Southwest Freeway Frontage Road
1 km · 59 sec · Southwest Freeway Frontage Road
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35
Turn right onto State Highway 6 South
6.8 mi · 11 min · State Highway 6 South
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36
Continue straight
1997 ft · 38 sec
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37
Continue straight
1.1 mi · 2 min
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38
Continue straight
1.8 mi · 3 min
-
39
Continue straight
1.3 mi · 2 min
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40
Continue straight
23.6 mi · 35 min
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41
Arrive at your destination
0 m · 1 sec · Highway 6
Car Route Details
A richer read on the saved driving route between Brownsville and Santa Fe.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
U.S. Highway 77
Continue on U.S. Highway 77
102 mi · 01h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Brownsville and Showers And Thunderstorms near Santa Fe.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Brownsville to Santa Fe?
The road trip is about 368.7 miles (593.3 km) and usually takes 07h 30m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Woodsboro is a useful midpoint, sitting about 184.6 miles from Brownsville and 184.1 miles from Santa Fe.
How much longer is the road route than the straight-line distance?
The direct path is about 281.2 miles (452.6 km), while the road route adds roughly 87.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $49.16 one way or $98.33 round trip. Estimated CO2 is about 115.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Brownsville and Showers And Thunderstorms near Santa Fe.
Flight Path Map
This map shows the direct air route between Brownsville and Santa Fe. Straight-line distance: 281.26 mi (452.65 km).
#1 Brownsville
The southernmost city in Texas.
| Population | 183,428 |
| Coordinates | 25.9017500, -97.4974800 |
| Altitude | 10 |
| Country | United States |
#2 Santa Fe
City in Galveston County, Texas, United States
| Population | 13,461 |
| Coordinates | 29.3780100, -95.1057600 |
| Altitude | 9 |
| Country | United States |
End: Santa Fe (-95.10576, 29.37801)
Estimated Travel Time
Distance: 593 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 17m |
| 40 mph (64.37 km/h) | 09h 13m |
| 50 mph (80.47 km/h) | 07h 22m |
| 60 mph (96.56 km/h) | 06h 08m |
| 70 mph (112.65 km/h) | 05h 16m |
| 80 mph (129 km/h) | 04h 35m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $49.16 | $98.33 |
| Mid-grade | $4.25 | $55.32 | $110.64 |
| Premium | $4.59 | $59.73 | $119.46 |
| Diesel | $3.99 | $51.95 | $103.90 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.