How far is Sanford, ME from Presque Isle, ME?
The driving distance from Sanford, ME to Presque Isle, ME is about 319.9 miles (514.9 km), with a travel time of about 05h 08m by car.
- The straight-line flight distance is about 261.3 miles (420.5 km).
- For a round trip, plan for roughly 10h 16m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 08m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Penobscot County, Maine, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Showers
Light Rain
Driving Route Map
The map below follows the saved road route between Sanford and Presque Isle.
Turn-by-Turn Driving Directions
Step-by-step road directions between Sanford and Presque Isle.
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1
Start on the route
27 m · 8 sec
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2
Turn right onto Washington Street
763 ft · 23 sec · Washington Street
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3
Continue on River Street
872 ft · 26 sec · River Street
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4
Turn right onto Cottage Street
1.2 mi · 3 min · Cottage Street
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5
Continue on Sanford Road
2.4 mi · 4 min · Sanford Road
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6
Continue on Biddeford Road
1.8 mi · 2 min · Biddeford Road
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7
Continue on Alfred Road
8.2 mi · 9 min · Alfred Road
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8
Continue on Alfred Street
1.4 mi · 2 min · Alfred Street
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9
Take the ramp left
735 ft · 1 min
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10
Keep slight right to continue on I 95 North Toll: Portland, Augusta
1317 ft · 33 sec
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11
Merge slight left onto Maine Turnpike
12.2 mi · 13 min · Maine Turnpike
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12
Keep slight right to continue on Downtown Portland
52.5 mi · 1 hr 1 min
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13
Merge slight left onto Maine Turnpike
198.3 mi · 3 hr 27 min · Maine Turnpike
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14
Take the exit slight right toward US 1: Houlton, Presque Isle
1444 ft · 43 sec
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15
Turn left onto North Street
3.2 mi · 6 min · North Street
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16
Continue on North Road
5.8 mi · 8 min · North Road
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17
Continue on US Highway 1
1.1 km · 55 sec · US Highway 1
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18
Continue on Route 1
6.4 mi · 10 min · Route 1
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19
Continue on Main Road
6.7 mi · 11 min · Main Road
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20
Continue on Route 1
2.7 mi · 4 min · Route 1
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21
Continue on Military Road
1649 ft · 40 sec · Military Road
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22
Continue on Main Street
2412 ft · 1 min · Main Street
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23
Turn left onto Benjamin Street
1.1 km · 2 min · Benjamin Street
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24
Continue on Presque Isle Road
2 mi · 3 min · Presque Isle Road
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25
Continue on Houlton Road
10.3 mi · 14 min · Houlton Road
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26
Continue on Main Street
1.3 mi · 4 min · Main Street
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27
Turn left onto State Street
30 m · 2 sec · State Street
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28
Arrive at your destination
0 m · 1 sec · State Street
Car Route Details
A richer read on the saved driving route between Sanford and Presque Isle.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Maine Turnpike
Merge slight left onto Maine Turnpike
198 mi · 03h 27m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Rain Showers leaving Sanford and Light Rain near Presque Isle.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Sanford to Presque Isle?
The road trip is about 319.9 miles (514.9 km) and usually takes 05h 08m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Bangor is a useful midpoint, sitting about 159.8 miles from Sanford and 160.2 miles from Presque Isle.
How much longer is the road route than the straight-line distance?
The direct path is about 261.3 miles (420.5 km), while the road route adds roughly 58.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 6:44 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $44.54 one way or $89.08 round trip. Estimated CO2 is about 100.3 kg one way.
What should you check before leaving?
Before you leave, expect Rain Showers around Sanford and Light Rain near Presque Isle.
Stop Ideas Near Bangor
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Bangor.
Bangor, Maine
Orono (University of Maine), Maine
Searsport, Maine
Belfast, Maine
Flight Path Map
This map shows the direct air route between Sanford and Presque Isle. Straight-line distance: 261.29 mi (420.51 km).
#1 Sanford
City in York County, Maine, United States
| Population | 21,253 |
| Coordinates | 43.4392500, -70.7742200 |
| Altitude | 92 |
| Country | United States |
#2 Presque Isle
City in Maine, United States
| Population | 8,950 |
| Coordinates | 46.6811500, -68.0158600 |
| Altitude | 139 |
| Country | United States |
End: State Street (-68.015848, 46.681243)
Estimated Travel Time
Distance: 515 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 39m |
| 40 mph (64.37 km/h) | 07h 59m |
| 50 mph (80.47 km/h) | 06h 23m |
| 60 mph (96.56 km/h) | 05h 19m |
| 70 mph (112.65 km/h) | 04h 34m |
| 80 mph (129 km/h) | 03h 59m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.95 | $44.54 | $89.08 |
| Mid-grade | $4.46 | $50.32 | $100.64 |
| Premium | $4.86 | $54.85 | $109.69 |
| Diesel | $6.00 | $67.71 | $135.41 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Maine · May 25, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.