How far is Sanford, ME from Greenville, ME?
The driving distance from Sanford, ME to Greenville, ME is about 187.4 miles (301.6 km), with a travel time of about 03h 56m by car.
- The straight-line flight distance is about 151.3 miles (243.5 km).
- For a round trip, plan for roughly 07h 52m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 56m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Maine, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers then Mostly Cloudy
Chance Light Rain
Driving Route Map
The map below follows the saved road route between Sanford and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Sanford and Greenville.
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1
Start on the route
27 m · 8 sec
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2
Turn right onto Washington Street
763 ft · 23 sec · Washington Street
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3
Continue on River Street
872 ft · 26 sec · River Street
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4
Turn right onto Cottage Street
1.2 mi · 3 min · Cottage Street
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5
Continue on Sanford Road
2.4 mi · 4 min · Sanford Road
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6
Continue on Biddeford Road
1.8 mi · 2 min · Biddeford Road
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7
Continue on Alfred Road
8.2 mi · 9 min · Alfred Road
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8
Continue on Alfred Street
1.4 mi · 2 min · Alfred Street
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9
Take the ramp left
735 ft · 1 min
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10
Keep slight right to continue on I 95 North Toll: Portland, Augusta
1317 ft · 33 sec
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11
Merge slight left onto Maine Turnpike
12.2 mi · 13 min · Maine Turnpike
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12
Keep slight right to continue on Downtown Portland
52.5 mi · 1 hr 1 min
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13
Merge slight left onto Maine Turnpike
53.6 mi · 58 min · Maine Turnpike
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14
Take the exit slight right toward ME 11, ME 100: Newport, Dexter
1611 ft · 46 sec
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15
Keep slight left
34 m · 7 sec
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16
Turn left onto Ox Bow Road
2725 ft · 1 min · Ox Bow Road
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17
Enter the roundabout and take exit 2 toward Moosehead Trail
37 m · 2 sec · Moosehead Trail
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18
Exit the roundabout onto Moosehead Trail
4.7 mi · 7 min · Moosehead Trail
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19
Continue on Newport Road
1.4 mi · 2 min · Newport Road
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20
Continue on Dexter Road
5.9 mi · 9 min · Dexter Road
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21
Continue on Corinna Road
1.2 mi · 2 min · Corinna Road
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22
Continue on Spring Street
1 mi · 2 min · Spring Street
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23
Continue on Church Street
1027 ft · 22 sec · Church Street
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24
Turn left onto Dam Street
89 m · 5 sec · Dam Street
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25
Continue on Grove Street
3106 ft · 53 sec · Grove Street
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26
Continue on Crockett Road
128 m · 7 sec · Crockett Road
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27
Turn straight onto North Dexter Road
9.4 mi · 14 min · North Dexter Road
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28
Continue on Main Street
1.4 km · 1 min · Main Street
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29
Continue on Bridge Street
626 ft · 19 sec · Bridge Street
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30
Turn left onto Water Street
1.3 mi · 2 min · Water Street
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31
Continue on South Main Street
150 m · 10 sec · South Main Street
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32
Turn right onto Elm Street
1.4 km · 1 min · Elm Street
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33
Continue on Main Road
6.3 mi · 9 min · Main Road
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34
Continue on Tenney Hill Road
4.1 mi · 6 min · Tenney Hill Road
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35
Continue on Greenville Road
10.2 mi · 15 min · Greenville Road
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36
Continue on Moosehead Lake Road
4.2 mi · 6 min · Moosehead Lake Road
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37
Turn right onto Pleasant Street
58 m · 8 sec · Pleasant Street
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38
Arrive at your destination
0 m · 1 sec · Pleasant Street
Car Route Details
A richer read on the saved driving route between Sanford and Greenville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Maine Turnpike
Merge slight left onto Maine Turnpike
53.6 mi · 00h 58m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Slight Chance Rain Showers then Mostly Cloudy leaving Sanford and Chance Light Rain near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Sanford to Greenville?
The road trip is about 187.4 miles (301.6 km) and usually takes 03h 56m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Sidney is a useful midpoint, sitting about 93.6 miles from Sanford and 93.8 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 151.3 miles (243.5 km), while the road route adds roughly 36.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 9:08 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $26.08 one way or $52.15 round trip. Estimated CO2 is about 58.7 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Rain Showers then Mostly Cloudy around Sanford and Chance Light Rain near Greenville.
Stop Ideas Near Sidney
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Waterville Opera House
Augusta City Hall
Inn At City Hall
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sidney.
Augusta, ME
Waldoboro, Maine
Damariscotta, Maine
Wiscasset, Maine
Flight Path Map
This map shows the direct air route between Sanford and Greenville. Straight-line distance: 151.3 mi (243.49 km).
#1 Sanford
City in York County, Maine, United States
| Population | 21,253 |
| Coordinates | 43.4392500, -70.7742200 |
| Altitude | 92 |
| Country | United States |
#2 Greenville
Town in Piscataquis County, Maine, United States
| Population | 1,628 |
| Coordinates | 45.4594900, -69.5906100 |
| Altitude | 318 |
| Country | United States |
End: Greenville (-69.59061, 45.45949)
Estimated Travel Time
Distance: 302 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 14m |
| 40 mph (64.37 km/h) | 04h 41m |
| 50 mph (80.47 km/h) | 03h 44m |
| 60 mph (96.56 km/h) | 03h 07m |
| 70 mph (112.65 km/h) | 02h 40m |
| 80 mph (129 km/h) | 02h 20m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.95 | $26.08 | $52.15 |
| Mid-grade | $4.46 | $29.46 | $58.92 |
| Premium | $4.86 | $32.11 | $64.22 |
| Diesel | $6.00 | $39.64 | $79.28 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Maine · May 03, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.