How far is San Antonio, FL from Port Saint Lucie, FL?
The driving distance from San Antonio, FL to Port Saint Lucie, FL is about 166.3 miles (267.7 km), with a travel time of about 02h 57m by car.
- The straight-line flight distance is about 137.9 miles (221.9 km).
- For a round trip, plan for roughly 05h 55m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM EDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 57m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Census designated place in Florida, USA
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between San Antonio and Port Saint Lucie.
Turn-by-Turn Driving Directions
Step-by-step road directions between San Antonio and Port Saint Lucie.
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1
Start on Pennsylvania Avenue
1115 ft · 37 sec · Pennsylvania Avenue
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2
Turn left onto College Avenue
117 m · 11 sec · College Avenue
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3
Enter the roundabout and take exit 2 toward Old State Road 52
31 m · 3 sec · Old State Road 52
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4
Exit the roundabout onto Old State Road 52
2 mi · 3 min · Old State Road 52
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5
Turn right onto Prospect Road
1448 ft · 42 sec · Prospect Road
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6
Turn left onto Clinton Avenue
3.1 mi · 5 min · Clinton Avenue
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7
Turn right
1587 ft · 35 sec
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8
Turn left
25.5 mi · 36 min
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9
Turn left
11.9 mi · 18 min
-
10
Continue on Broadway Avenue
3183 ft · 1 min · Broadway Avenue
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11
Turn left onto Van Fleet Drive
2787 ft · 1 min · Van Fleet Drive
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12
Continue straight
1427 ft · 27 sec
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13
Continue straight
10.8 mi · 14 min
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14
Continue straight
4.3 mi · 6 min
-
15
Continue straight
46.4 mi · 59 min
-
16
Take the exit left
784 ft · 19 sec
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17
Continue straight
90 m · 7 sec
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18
Keep slight right to continue on Florida's Turnpike South: Miami
926 ft · 23 sec
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19
Merge slight left onto Florida's Turnpike
49.8 mi · 53 min · Florida's Turnpike
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20
Take the exit slight right toward Port Saint Lucie
1 mi · 3 min
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21
Continue on Southwest Bayshore Boulevard
147 m · 15 sec · Southwest Bayshore Boulevard
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22
Turn right onto Southwest Port Saint Lucie Boulevard
1.4 km · 2 min · Southwest Port Saint Lucie Boulevard
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23
Turn left onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
-
24
Turn left onto Southwest Carter Avenue
66 m · 9 sec · Southwest Carter Avenue
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25
Arrive at your destination
0 m · 1 sec · Southwest Carter Avenue
Car Route Details
A richer read on the saved driving route between San Antonio and Port Saint Lucie.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Florida's Turnpike
Merge slight left onto Florida's Turnpike
49.8 mi · 00h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving San Antonio and Sunny near Port Saint Lucie.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from San Antonio to Port Saint Lucie?
The road trip is about 166.3 miles (267.7 km) and usually takes 02h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Babson Park is a useful midpoint, sitting about 80 miles from San Antonio and 86.2 miles from Port Saint Lucie.
How much longer is the road route than the straight-line distance?
The direct path is about 137.9 miles (221.9 km), while the road route adds roughly 28.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM EDT. If you want a more comfortable same-day return, try to leave by 12:34 PM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.35 one way or $48.70 round trip. Estimated CO2 is about 52.2 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around San Antonio and Sunny near Port Saint Lucie.
Stop Ideas Near Babson Park
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Babson Park.
Winter Haven
Sebring
Lakeland
Lakeland
Flight Path Map
This map shows the direct air route between San Antonio and Port Saint Lucie. Straight-line distance: 137.88 mi (221.9 km).
#1 San Antonio
City in Pasco County, Florida, USA
| Population | 1,506 |
| Coordinates | 28.3361100, -82.2745300 |
| Altitude | 51 |
| Country | United States |
#2 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
End: Southwest Carter Avenue (-80.350328, 27.294381)
Estimated Travel Time
Distance: 268 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 32m |
| 40 mph (64.37 km/h) | 04h 09m |
| 50 mph (80.47 km/h) | 03h 19m |
| 60 mph (96.56 km/h) | 02h 46m |
| 70 mph (112.65 km/h) | 02h 22m |
| 80 mph (129 km/h) | 02h 04m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $24.35 | $48.70 |
| Mid-grade | $4.60 | $26.98 | $53.96 |
| Premium | $4.90 | $28.74 | $57.48 |
| Diesel | $4.35 | $25.53 | $51.07 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.