How far is North Myrtle Beach, SC from Greenville, SC?
The driving distance from North Myrtle Beach, SC to Greenville, SC is about 264.8 miles (426.2 km), with a travel time of about 04h 11m by car.
- The straight-line flight distance is about 223.6 miles (359.9 km).
- For a round trip, plan for roughly 08h 22m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 11m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between North Myrtle Beach and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between North Myrtle Beach and Greenville.
-
1
Start on 6th Avenue South
1.1 km · 2 min · 6th Avenue South
-
2
Turn right onto US Highway 17 South
1822 ft · 41 sec · US Highway 17 South
-
3
Turn left onto Robert Edge Parkway
1.9 mi · 3 min · Robert Edge Parkway
-
4
Turn left onto SC 31 South: US 501, Myrtle Beach
1749 ft · 42 sec
-
5
Merge slight left onto Carolina Bays Parkway
4.4 mi · 5 min · Carolina Bays Parkway
-
6
Take the exit slight right toward SC 22: Myrtle Beach, Conway
2312 ft · 56 sec
-
7
Keep slight right to continue on SC 22 West: Conway
1.1 km · 1 min
-
8
Merge slight left onto Veterans Highway
25.9 mi · 30 min · Veterans Highway
-
9
Keep slight right to continue on US 501 North: Aynor, Marion
952 ft · 23 sec
-
10
Merge slight left
21 mi · 24 min
-
11
Turn straight
3.2 mi · 4 min
-
12
Continue straight
6.7 mi · 8 min
-
13
Continue straight
12.1 mi · 17 min
-
14
Turn slight right onto East Cheves Street
1.7 mi · 4 min · East Cheves Street
-
15
Turn right onto Warley Street
644 ft · 18 sec · Warley Street
-
16
Turn left onto West Evans Street
2.4 mi · 5 min · West Evans Street
-
17
Turn right onto West David H McLeod Boulevard
1.5 mi · 3 min · West David H McLeod Boulevard
-
18
Continue on J Strom Thurmond Freeway
76.4 mi · 1 hr 25 min · J Strom Thurmond Freeway
-
19
Take the exit slight right toward I 26 West
1.7 mi · 4 min
-
20
Merge slight left
54.8 mi · 1 hr
-
21
Keep slight left to continue on I 385 North: Laurens, Greenville
29.6 mi · 32 min
-
22
Keep slight left to continue on Golden Strip Freeway
12.4 mi · 15 min · Golden Strip Freeway
-
23
Continue on East North Street
1270 ft · 19 sec · East North Street
-
24
Continue on Beattie Place
1231 ft · 27 sec · Beattie Place
-
25
Turn right onto North Church Street
18 m · 2 sec · North Church Street
-
26
Arrive at your destination
0 m · 1 sec · North Church Street
Car Route Details
A richer read on the saved driving route between North Myrtle Beach and Greenville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
J Strom Thurmond Freeway
Continue on J Strom Thurmond Freeway
76.4 mi · 01h 25m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving North Myrtle Beach and Mostly Sunny near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from North Myrtle Beach to Greenville?
The road trip is about 264.8 miles (426.2 km) and usually takes 04h 11m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Camden is a useful midpoint, sitting about 129.4 miles from North Myrtle Beach and 135.5 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 223.6 miles (359.9 km), while the road route adds roughly 41.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:38 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $37.04 one way or $74.07 round trip. Estimated CO2 is about 83.1 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around North Myrtle Beach and Mostly Sunny near Greenville.
Stop Ideas Near Camden
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Camden.
Camden
Columbia
Florence
Kingstree
Flight Path Map
This map shows the direct air route between North Myrtle Beach and Greenville. Straight-line distance: 223.66 mi (359.94 km).
#1 North Myrtle Beach
City in Horry County, South Carolina, United States of America
| Population | 17,280 |
| Coordinates | 33.8160100, -78.6800200 |
| Altitude | 2 |
| Country | United States |
#2 Greenville
The most populous city in Greenville County, South Carolina.
| Population | 72,227 |
| Coordinates | 34.8526200, -82.3940100 |
| Altitude | 307 |
| Country | United States |
End: North Church Street (-82.394165, 34.852668)
Estimated Travel Time
Distance: 426 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 49m |
| 40 mph (64.37 km/h) | 06h 37m |
| 50 mph (80.47 km/h) | 05h 17m |
| 60 mph (96.56 km/h) | 04h 24m |
| 70 mph (112.65 km/h) | 03h 47m |
| 80 mph (129 km/h) | 03h 18m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $37.04 | $74.07 |
| Mid-grade | $4.43 | $41.41 | $82.82 |
| Premium | $4.78 | $44.67 | $89.35 |
| Diesel | $5.62 | $52.58 | $105.17 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.