How far is Mesquite, TX from Brownsville, TX?
The driving distance from Mesquite, TX to Brownsville, TX is about 533.6 miles (858.7 km), with a travel time of about 09h 43m by car.
- The straight-line flight distance is about 477.4 miles (768.3 km).
- For a round trip, plan for roughly 19h 26m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 09h 43m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
37th President of the United States of America (1913-1994)
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Mesquite and Brownsville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mesquite and Brownsville.
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1
Start on South Galloway Avenue
1 m · 7 sec · South Galloway Avenue
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2
Turn left onto West Main Street
2020 ft · 57 sec · West Main Street
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3
Continue on Scyene Road
1 mi · 2 min · Scyene Road
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4
Turn left onto Rodeo Center Boulevard
697 ft · 26 sec · Rodeo Center Boulevard
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5
Turn slight left onto I 635 South
1339 ft · 33 sec
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6
Merge slight left onto Lyndon B Johnson Freeway
16.7 mi · 18 min · Lyndon B Johnson Freeway
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7
Take the exit slight right toward I 35E South: Waco
1.6 km · 2 min
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8
Merge slight left onto South R L Thornton Freeway
80.3 mi · 1 hr 22 min · South R L Thornton Freeway
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9
Continue on North Jack Kultgen Expressway
6.6 mi · 8 min · North Jack Kultgen Expressway
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10
Continue on Purple Heart Trail
37.9 mi · 39 min · Purple Heart Trail
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11
Keep slight left
26.5 mi · 27 min
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12
Take the exit slight right toward TX 130 Toll South: San Antonio
1.1 km · 56 sec
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13
Continue straight
58.5 mi · 55 min
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14
Take the exit slight right toward US 183 South: Lockhart
1219 ft · 30 sec
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15
Continue on United States Highway 183
2699 ft · 35 sec · United States Highway 183
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16
Continue on North Colorado Street
4.9 mi · 9 min · North Colorado Street
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17
Continue on US 183
10.1 mi · 12 min · US 183
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18
Continue on North Magnolia Avenue
4.2 mi · 7 min · North Magnolia Avenue
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19
Continue straight
51.2 mi · 57 min
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20
Turn slight left onto Farm-to-Market Road 792
8.4 mi · 11 min · Farm-to-Market Road 792
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21
Continue on East Main Street
1.3 km · 1 min · East Main Street
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22
Turn left onto South Sunset Strip Drive
1.2 mi · 1 min · South Sunset Strip Drive
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23
Continue on South US Highway 181
40.2 mi · 46 min · South US Highway 181
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24
Continue on North 8th Street
1.3 km · 56 sec · North 8th Street
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25
Continue on US Highway 181 South
16.1 mi · 18 min · US Highway 181 South
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26
Take the exit slight right
1648 ft · 45 sec
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27
Keep slight right to continue on US Route 181
65 m · 6 sec · US Route 181
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28
Turn straight onto US Highway 181
1.1 km · 1 min · US Highway 181
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29
Take the ramp right
1926 ft · 47 sec
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30
Merge slight left
11.9 mi · 14 min
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31
Take the exit straight toward I 37, US 77, I 69E
538 ft · 13 sec
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32
Keep slight left
1965 ft · 48 sec
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33
Merge slight right
2.5 mi · 2 min
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34
Take the exit slight right toward I 69E, US 77: Kingsville, Brownsville
31.3 mi · 34 min
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35
Keep slight left to continue on U.S. Highway 77
61.3 mi · 1 hr 9 min · U.S. Highway 77
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36
Keep slight left to continue on U.S. Highway 77
43.7 mi · 47 min · U.S. Highway 77
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37
Continue on North Expressway
2.1 mi · 2 min · North Expressway
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38
Keep slight left to continue on North Expressway
9 mi · 10 min · North Expressway
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39
Take the exit slight right toward 12th-14th Street
1730 ft · 42 sec
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40
Turn straight onto South Expressway
101 m · 9 sec · South Expressway
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41
Turn right onto East 12th Street
1.2 km · 2 min · East 12th Street
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42
Turn right onto East Washington Street
9 m · 1 sec · East Washington Street
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43
Arrive at your destination
0 m · 1 sec · East Washington Street
Car Route Details
A richer read on the saved driving route between Mesquite and Brownsville.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
South R L Thornton Freeway
Merge slight left onto South R L Thornton Freeway
80.3 mi · 01h 22m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Mesquite and Mostly Sunny near Brownsville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mesquite to Brownsville?
The road trip is about 533.6 miles (858.7 km) and usually takes 09h 43m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Nixon is a useful midpoint, sitting about 267.4 miles from Mesquite and 266.2 miles from Brownsville.
How much longer is the road route than the straight-line distance?
The direct path is about 477.4 miles (768.3 km), while the road route adds roughly 56.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $71.16 one way or $142.32 round trip. Estimated CO2 is about 167.3 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Mesquite and Mostly Sunny near Brownsville.
Stop Ideas Near Nixon
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Nixon.
San Marcos Station
San Antonio Station
Austin
Flight Path Map
This map shows the direct air route between Mesquite and Brownsville. Straight-line distance: 477.4 mi (768.3 km).
#1 Mesquite
The ninth most populous city in Texas.
| Population | 138,916 |
| Coordinates | 32.7668000, -96.5991600 |
| Altitude | 151 |
| Country | United States |
#2 Brownsville
The southernmost city in Texas.
| Population | 183,428 |
| Coordinates | 25.9017500, -97.4974800 |
| Altitude | 10 |
| Country | United States |
End: Brownsville (-97.49748, 25.90175)
Estimated Travel Time
Distance: 859 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 17h 46m |
| 40 mph (64.37 km/h) | 13h 20m |
| 50 mph (80.47 km/h) | 10h 40m |
| 60 mph (96.56 km/h) | 08h 53m |
| 70 mph (112.65 km/h) | 07h 37m |
| 80 mph (129 km/h) | 06h 39m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $71.16 | $142.32 |
| Mid-grade | $4.25 | $80.07 | $160.13 |
| Premium | $4.59 | $86.45 | $172.90 |
| Diesel | $3.99 | $75.19 | $150.38 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · May 04, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.