How far is Mesquite, TX from Laredo, TX?
The driving distance from Mesquite, TX to Laredo, TX is about 454.5 miles (731.5 km), with a travel time of about 06h 33m by car.
- The straight-line flight distance is about 402.8 miles (648.3 km).
- For a round trip, plan for roughly 13h 06m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 33m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Hays County, Texas, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms
Partly Sunny
Driving Route Map
The map below follows the saved road route between Mesquite and Laredo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mesquite and Laredo.
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1
Start on South Galloway Avenue
1 m · 7 sec · South Galloway Avenue
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2
Turn left onto West Main Street
2020 ft · 57 sec · West Main Street
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3
Continue on Scyene Road
1 mi · 2 min · Scyene Road
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4
Turn left onto Rodeo Center Boulevard
697 ft · 26 sec · Rodeo Center Boulevard
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5
Turn slight left onto I 635 South
1339 ft · 33 sec
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6
Merge slight left onto Lyndon B Johnson Freeway
16.7 mi · 18 min · Lyndon B Johnson Freeway
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7
Take the exit slight right toward I 35E South: Waco
1.6 km · 2 min
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8
Merge slight left onto South R L Thornton Freeway
80.3 mi · 1 hr 22 min · South R L Thornton Freeway
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9
Continue on North Jack Kultgen Expressway
6.6 mi · 8 min · North Jack Kultgen Expressway
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10
Continue on Purple Heart Trail
37.9 mi · 39 min · Purple Heart Trail
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11
Keep slight left
55.8 mi · 59 min
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12
Keep slight left to continue on Purple Heart Trail
49.8 mi · 55 min · Purple Heart Trail
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13
Continue on Interstate Highway 35
1.7 mi · 2 min · Interstate Highway 35
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14
Continue on Purple Heart Trail
11.9 mi · 13 min · Purple Heart Trail
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15
Continue on North Pan Am Expressway
10 mi · 12 min · North Pan Am Expressway
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16
Keep slight left to continue on North Pan Am Expressway
6.4 mi · 8 min · North Pan Am Expressway
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17
Keep slight left to continue on North Pan Am Expressway
2.1 mi · 3 min · North Pan Am Expressway
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18
Keep slight right to continue on South Pan Am Expressway
10.4 mi · 12 min · South Pan Am Expressway
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19
Continue on Purple Heart Trail
144.5 mi · 2 hr 26 min · Purple Heart Trail
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20
Turn right onto Houston Street
1607 ft · 42 sec · Houston Street
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21
Turn left onto Salinas Avenue
83 m · 12 sec · Salinas Avenue
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22
Turn left onto Matamoros Street
93 m · 5 sec · Matamoros Street
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23
Arrive at your destination
0 m · 1 sec · Matamoros Street
Car Route Details
A richer read on the saved driving route between Mesquite and Laredo.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Purple Heart Trail
Continue on Purple Heart Trail
144 mi · 02h 26m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms leaving Mesquite and Partly Sunny near Laredo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mesquite to Laredo?
The road trip is about 454.5 miles (731.5 km) and usually takes 06h 33m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Buda is a useful midpoint, sitting about 219 miles from Mesquite and 235.5 miles from Laredo.
How much longer is the road route than the straight-line distance?
The direct path is about 402.8 miles (648.3 km), while the road route adds roughly 51.7 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $60.62 one way or $121.23 round trip. Estimated CO2 is about 142.5 kg one way.
What should you check before leaving?
Before you leave, expect Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms around Mesquite and Partly Sunny near Laredo.
Stop Ideas Near Buda
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Buda.
Austin
San Marcos Station
Taylor
San Antonio Station
Flight Path Map
This map shows the direct air route between Mesquite and Laredo. Straight-line distance: 402.82 mi (648.27 km).
#1 Mesquite
The ninth most populous city in Texas.
| Population | 138,916 |
| Coordinates | 32.7668000, -96.5991600 |
| Altitude | 151 |
| Country | United States |
#2 Laredo
The third most populous city in Texas and the center of the Laredo metropolitan area.
| Population | 263,640 |
| Coordinates | 27.5064100, -99.5075400 |
| Altitude | 126 |
| Country | United States |
End: Matamoros Street (-99.507507, 27.506385)
Estimated Travel Time
Distance: 732 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 15h 08m |
| 40 mph (64.37 km/h) | 11h 21m |
| 50 mph (80.47 km/h) | 09h 05m |
| 60 mph (96.56 km/h) | 07h 34m |
| 70 mph (112.65 km/h) | 06h 29m |
| 80 mph (129 km/h) | 05h 40m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.78 | $60.62 | $121.23 |
| Mid-grade | $4.25 | $68.20 | $136.40 |
| Premium | $4.59 | $73.64 | $147.28 |
| Diesel | $3.99 | $64.05 | $128.10 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Texas · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.