How far is Medicine Lodge, KS from Kansas City, KS?
The driving distance from Medicine Lodge, KS to Kansas City, KS is about 280.8 miles (451.9 km), with a travel time of about 04h 22m by car.
- The straight-line flight distance is about 249.2 miles (401 km).
- For a round trip, plan for roughly 08h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 22m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Butler County, Kansas, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Sunny
Driving Route Map
The map below follows the saved road route between Medicine Lodge and Kansas City.
Turn-by-Turn Driving Directions
Step-by-step road directions between Medicine Lodge and Kansas City.
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1
Start on the route
20 m · 7 sec
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2
Turn right
64 m · 20 sec
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3
Turn left onto West Kansas Avenue
65 m · 11 sec · West Kansas Avenue
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4
Turn right onto South Main Street
1758 ft · 54 sec · South Main Street
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5
Turn left onto East Fowler Avenue
20.8 mi · 31 min · East Fowler Avenue
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6
Continue on Hershey Highway
10.1 mi · 15 min · Hershey Highway
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7
Turn left
2.9 mi · 4 min
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8
Keep slight left
699 ft · 14 sec
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9
Turn right onto West 14th Street
15 mi · 22 min · West 14th Street
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10
Continue on West 10th Avenue
14.3 mi · 21 min · West 10th Avenue
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11
Continue on West 15th Street
6.3 mi · 10 min · West 15th Street
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12
Turn left onto North G Street
2461 ft · 1 min · North G Street
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13
Turn right
2200 ft · 39 sec
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14
Enter the roundabout and take exit 1 toward the route
34 m · 2 sec
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15
Exit the roundabout
3.1 mi · 5 min
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16
Take the ramp left
669 ft · 16 sec
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17
Keep slight right
1506 ft · 37 sec
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18
Merge slight left onto Kansas Turnpike
107.2 mi · 1 hr 47 min · Kansas Turnpike
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19
Keep slight left to continue on Kansas Turnpike
110.7 mi · 1 hr 52 min · Kansas Turnpike
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20
Keep slight right to continue on I 70 East, US 24 East, US 40 East, US 69 North: Saint Louis
1600 ft · 25 sec
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21
Take the exit slight right toward US 69 North, US 169 South
943 ft · 21 sec
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22
Turn left onto South 7th Street Trafficway
1.5 mi · 4 min · South 7th Street Trafficway
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23
Turn left onto Armstrong Avenue
86 m · 18 sec · Armstrong Avenue
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24
Turn left
45 m · 11 sec
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25
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Medicine Lodge and Kansas City.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Kansas Turnpike
Keep slight left to continue on Kansas Turnpike
111 mi · 01h 52m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Medicine Lodge and Sunny near Kansas City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Medicine Lodge to Kansas City?
The road trip is about 280.8 miles (451.9 km) and usually takes 04h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Cassoday is a useful midpoint, sitting about 147 miles from Medicine Lodge and 133.7 miles from Kansas City.
How much longer is the road route than the straight-line distance?
The direct path is about 249.2 miles (401 km), while the road route adds roughly 31.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:14 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $37.37 one way or $74.74 round trip. Estimated CO2 is about 88.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Medicine Lodge and Sunny near Kansas City.
Stop Ideas Near Cassoday
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Cassoday.
Newton
Hutchinson
Flight Path Map
This map shows the direct air route between Medicine Lodge and Kansas City. Straight-line distance: 249.18 mi (401.02 km).
#1 Medicine Lodge
City in Barber County, Kansas, United States
| Population | 1,804 |
| Coordinates | 37.2811300, -98.5803600 |
| Altitude | 456 |
| Country | United States |
#2 Kansas City
The second most populous city in Kansas.
| Population | 152,960 |
| Coordinates | 39.1141700, -94.6274600 |
| Altitude | 266 |
| Country | United States |
End: Armstrong Avenue (-94.627458, 39.114578)
Estimated Travel Time
Distance: 452 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 21m |
| 40 mph (64.37 km/h) | 07h 01m |
| 50 mph (80.47 km/h) | 05h 36m |
| 60 mph (96.56 km/h) | 04h 40m |
| 70 mph (112.65 km/h) | 04h 00m |
| 80 mph (129 km/h) | 03h 30m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $37.37 | $74.74 |
| Mid-grade | $4.25 | $42.15 | $84.29 |
| Premium | $4.65 | $46.12 | $92.24 |
| Diesel | $5.30 | $52.56 | $105.13 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Kansas · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.