How far is Hilton Head, SC from Greenville, SC?
The driving distance from Hilton Head, SC to Greenville, SC is about 252 miles (405.6 km), with a travel time of about 04h 01m by car.
- The straight-line flight distance is about 205.2 miles (330.3 km).
- For a round trip, plan for roughly 08h 02m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 01m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Calhoun County, South Carolina
Route Weather Snapshot
Check the forecast at both ends before you head out.
Partly Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Hilton Head and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between Hilton Head and Greenville.
-
1
Start on William Hilton Parkway
1601 ft · 29 sec · William Hilton Parkway
-
2
Continue on William Hilton Parkway
3.8 mi · 4 min · William Hilton Parkway
-
3
Continue on Fording Island Road
9 mi · 13 min · Fording Island Road
-
4
Take the exit slight right
1444 ft · 40 sec
-
5
Keep slight right
45 m · 4 sec
-
6
Merge slight left onto Okatie Highway
3.9 mi · 5 min · Okatie Highway
-
7
Take the exit slight left
149 m · 14 sec
-
8
Continue on Lowcountry Drive
7.9 mi · 11 min · Lowcountry Drive
-
9
Continue on Coosaw Scenic Drive
9.4 mi · 13 min · Coosaw Scenic Drive
-
10
Take the ramp slight right toward I 95 North, US 17 North: Florence
1435 ft · 35 sec
-
11
Merge slight left
57.2 mi · 1 hr 1 min
-
12
Take the exit slight right toward I 26 West: Columbia
1864 ft · 1 min
-
13
Merge slight left
116.6 mi · 2 hr 7 min
-
14
Keep slight left to continue on I 385 North: Laurens, Greenville
29.6 mi · 32 min
-
15
Keep slight left to continue on Golden Strip Freeway
12.4 mi · 15 min · Golden Strip Freeway
-
16
Continue on East North Street
1270 ft · 19 sec · East North Street
-
17
Continue on Beattie Place
1231 ft · 27 sec · Beattie Place
-
18
Turn right onto North Church Street
18 m · 2 sec · North Church Street
-
19
Arrive at your destination
0 m · 1 sec · North Church Street
Car Route Details
A richer read on the saved driving route between Hilton Head and Greenville.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 26 West
Merge slight left
117 mi · 02h 07m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Partly Sunny leaving Hilton Head and Mostly Sunny near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Hilton Head to Greenville?
The road trip is about 252 miles (405.6 km) and usually takes 04h 01m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Saint Matthews is a useful midpoint, sitting about 125.9 miles from Hilton Head and 126.1 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 205.2 miles (330.3 km), while the road route adds roughly 46.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 8:58 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $35.21 one way or $70.43 round trip. Estimated CO2 is about 79 kg one way.
What should you check before leaving?
Before you leave, expect Partly Sunny around Hilton Head and Mostly Sunny near Greenville.
Stop Ideas Near Saint Matthews
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Saint Matthews.
Columbia
Denmark
Camden
Kingstree
Flight Path Map
This map shows the direct air route between Hilton Head and Greenville. Straight-line distance: 205.21 mi (330.26 km).
#1 Hilton Head
Resort town in South Carolina, USA
| Population | 37,099 |
| Coordinates | 32.2163200, -80.7526100 |
| Altitude | 3 |
| Country | United States |
#2 Greenville
The most populous city in Greenville County, South Carolina.
| Population | 72,227 |
| Coordinates | 34.8526200, -82.3940100 |
| Altitude | 307 |
| Country | United States |
End: North Church Street (-82.394165, 34.852668)
Estimated Travel Time
Distance: 406 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 23m |
| 40 mph (64.37 km/h) | 06h 18m |
| 50 mph (80.47 km/h) | 05h 02m |
| 60 mph (96.56 km/h) | 04h 12m |
| 70 mph (112.65 km/h) | 03h 36m |
| 80 mph (129 km/h) | 03h 08m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $35.21 | $70.43 |
| Mid-grade | $4.43 | $39.37 | $78.75 |
| Premium | $4.78 | $42.48 | $84.95 |
| Diesel | $5.62 | $50.00 | $99.99 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · May 17, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.