How far is Greenville, WI from North La Crosse, WI?
The driving distance from Greenville, WI to North La Crosse, WI is about 161.2 miles (259.5 km), with a travel time of about 02h 57m by car.
- The straight-line flight distance is about 138.2 miles (222.4 km).
- For a round trip, plan for roughly 05h 54m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 57m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Adams County, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Likely
Chance Showers And Thunderstorms then Chance Rain And Snow Showers
Driving Route Map
The map below follows the saved road route between Greenville and North La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and North La Crosse.
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1
Start on Greenville Drive
10 m · 3 sec · Greenville Drive
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2
Turn left onto Municipal Drive
1.4 km · 2 min · Municipal Drive
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3
Enter the roundabout and take exit 2 toward Municipal Drive
43 m · 3 sec · Municipal Drive
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4
Exit the roundabout onto Municipal Drive
1.6 km · 2 min · Municipal Drive
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5
Turn right onto Wisconsin Avenue
6.7 mi · 10 min · Wisconsin Avenue
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6
Continue on State Road 96
1.1 mi · 2 min · State Road 96
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7
Continue on Wisconsin Avenue
2.3 mi · 3 min · Wisconsin Avenue
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8
Enter the roundabout and take exit 2 toward State Highway 96
41 m · 8 sec · State Highway 96
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9
Exit the roundabout onto State Highway 96
1.8 mi · 3 min · State Highway 96
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10
Continue on State Road 96
3.9 mi · 5 min · State Road 96
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11
Continue on State Highway 110
3.2 mi · 5 min · State Highway 110
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12
Continue on State Highway 49
8.8 mi · 13 min · State Highway 49
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13
Turn right onto County Road M
2 mi · 5 min · County Road M
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14
Continue on County Road M
2674 ft · 1 min · County Road M
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15
Continue on County Road M
3 mi · 7 min · County Road M
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16
At the end of the road, turn right onto County Highway E
620 ft · 22 sec · County Highway E
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17
Turn left onto County Highway A
8.1 mi · 12 min · County Highway A
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18
At the end of the road, turn left onto State Highway 22
8.7 mi · 13 min · State Highway 22
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19
Turn right onto West Main Street
763 ft · 32 sec · West Main Street
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20
Turn left onto South Cambridge Street
1 km · 1 min · South Cambridge Street
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21
Turn right onto West Bird Avenue
785 ft · 40 sec · West Bird Avenue
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22
Turn left onto State Highway 21
12.3 mi · 17 min · State Highway 21
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23
Continue on Wautoma Road
2396 ft · 50 sec · Wautoma Road
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24
Continue on East Follett Drive
28.9 mi · 41 min · East Follett Drive
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25
Continue on East 3rd Street
10.9 mi · 16 min · East 3rd Street
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26
Continue on State Highway 21
11 mi · 15 min · State Highway 21
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27
Continue on East McCoy Boulevard
1684 ft · 34 sec · East McCoy Boulevard
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28
Continue on State Highway 21
640 ft · 12 sec · State Highway 21
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29
Take the exit straight
1644 ft · 42 sec
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30
Merge slight left
2.8 mi · 3 min
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31
Take the exit slight right toward I 90 West: La Crosse, Albert Lea
1.2 km · 51 sec
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32
Merge slight left
41 mi · 44 min
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33
Take the exit slight right toward US 53 South, WI 35: La Crosse, Onalaska
1291 ft · 37 sec
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34
Turn left onto Rose Street
1.6 mi · 3 min · Rose Street
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35
Arrive at your destination
0 m · 1 sec · Rose Street
Car Route Details
A richer read on the saved driving route between Greenville and North La Crosse.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 90 West
Merge slight left
41 mi · 00h 44m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Rain Likely leaving Greenville and Chance Showers And Thunderstorms then Chance Rain And Snow Showers near North La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to North La Crosse?
The road trip is about 161.2 miles (259.5 km) and usually takes 02h 57m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Friendship is a useful midpoint, sitting about 81.6 miles from Greenville and 79.7 miles from North La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 138.2 miles (222.4 km), while the road route adds roughly 23 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 12:36 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.46 one way or $42.91 round trip. Estimated CO2 is about 50.6 kg one way.
What should you check before leaving?
Before you leave, expect Rain Likely around Greenville and Chance Showers And Thunderstorms then Chance Rain And Snow Showers near North La Crosse.
Stop Ideas Near Friendship
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Friendship.
Westfield, WI
Wisconsin Dells
Wisconsin Rapids, WI
Portage
Flight Path Map
This map shows the direct air route between Greenville and North La Crosse. Straight-line distance: 138.21 mi (222.42 km).
#1 Greenville
Town in Outagamie County, Wisconsin, United States
| Population | 12,529 |
| Coordinates | 44.3002600, -88.5365000 |
| Altitude | 248 |
| Country | United States |
#2 North La Crosse
A city in La Crosse County, Wisconsin.
| Population | 50,470 |
| Coordinates | 43.8463500, -91.2481900 |
| Altitude | 197 |
| Country | United States |
End: Rose Street (-91.248268, 43.846348)
Estimated Travel Time
Distance: 259 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 22m |
| 40 mph (64.37 km/h) | 04h 01m |
| 50 mph (80.47 km/h) | 03h 13m |
| 60 mph (96.56 km/h) | 02h 41m |
| 70 mph (112.65 km/h) | 02h 18m |
| 80 mph (129 km/h) | 02h 00m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $21.46 | $42.91 |
| Mid-grade | $4.25 | $24.20 | $48.40 |
| Premium | $4.65 | $26.48 | $52.96 |
| Diesel | $5.30 | $30.18 | $60.36 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.