How far is North La Crosse, WI from Greenville, WI?
The driving distance from North La Crosse, WI to Greenville, WI is about 166.5 miles (268 km), with a travel time of about 03h 47m by car.
- The straight-line flight distance is about 138.2 miles (222.4 km).
- For a round trip, plan for roughly 07h 35m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 47m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Adams County, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms then Chance Rain And Snow Showers
Rain Likely
Driving Route Map
The map below follows the saved road route between North La Crosse and Greenville.
Turn-by-Turn Driving Directions
Step-by-step road directions between North La Crosse and Greenville.
-
1
Start on Rose Street
1.2 mi · 3 min · Rose Street
-
2
Take the exit slight right
14 mi · 15 min
-
3
Continue straight
44.4 mi · 48 min
-
4
Take the exit slight right toward WI 80: Necedah, New Lisbon
901 ft · 22 sec
-
5
Keep slight left
28 m · 7 sec
-
6
Turn left onto East Bridge Street
2144 ft · 40 sec · East Bridge Street
-
7
Continue on State Highway 80
6.8 mi · 9 min · State Highway 80
-
8
At the end of the road, turn left onto State Highway 80
2.8 mi · 4 min · State Highway 80
-
9
Continue on South Main Street
1.2 mi · 2 min · South Main Street
-
10
Turn right onto West 3rd Street
1.6 km · 2 min · West 3rd Street
-
11
Continue on State Highway 21
28.9 mi · 41 min · State Highway 21
-
12
Continue on Wautoma Road
2396 ft · 50 sec · Wautoma Road
-
13
Continue on State Highway 21
12.3 mi · 17 min · State Highway 21
-
14
Turn left onto South Cambridge Street
2885 ft · 1 min · South Cambridge Street
-
15
Turn right onto West Main Street
750 ft · 32 sec · West Main Street
-
16
Turn left onto State Highway 22
8.7 mi · 13 min · State Highway 22
-
17
Turn right onto County Highway A
8.1 mi · 11 min · County Highway A
-
18
At the end of the road, turn right onto County Highway E
620 ft · 22 sec · County Highway E
-
19
Turn left onto County Road M
3 mi · 7 min · County Road M
-
20
Continue on County Road M
2674 ft · 1 min · County Road M
-
21
Continue on County Road M
2 mi · 5 min · County Road M
-
22
Turn left onto State Highway 49
8.8 mi · 13 min · State Highway 49
-
23
Continue on State Highway 110
3.2 mi · 5 min · State Highway 110
-
24
Continue on State Road 96
3.9 mi · 5 min · State Road 96
-
25
Continue on State Highway 96
1.8 mi · 3 min · State Highway 96
-
26
Enter the roundabout and take exit 2 toward Wisconsin Avenue
40 m · 7 sec · Wisconsin Avenue
-
27
Exit the roundabout onto Wisconsin Avenue
2.3 mi · 3 min · Wisconsin Avenue
-
28
Continue on State Road 96
1.1 mi · 2 min · State Road 96
-
29
Continue on Wisconsin Avenue
6.7 mi · 10 min · Wisconsin Avenue
-
30
Turn left onto Municipal Drive
1.6 km · 2 min · Municipal Drive
-
31
Enter the roundabout and take exit 2 toward Municipal Drive
38 m · 3 sec · Municipal Drive
-
32
Exit the roundabout onto Municipal Drive
1.3 km · 1 min · Municipal Drive
-
33
Turn right onto Greenville Drive
562 ft · 42 sec · Greenville Drive
-
34
Continue on Greenville Drive
141 m · 9 sec · Greenville Drive
-
35
Arrive at your destination
0 m · 1 sec · Greenville Drive
Car Route Details
A richer read on the saved driving route between North La Crosse and Greenville.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Rose Street
Continue straight
44.4 mi · 00h 48m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms then Chance Rain And Snow Showers leaving North La Crosse and Rain Likely near Greenville.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from North La Crosse to Greenville?
The road trip is about 166.5 miles (268 km) and usually takes 03h 47m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Friendship is a useful midpoint, sitting about 83.1 miles from North La Crosse and 83.5 miles from Greenville.
How much longer is the road route than the straight-line distance?
The direct path is about 138.2 miles (222.4 km), while the road route adds roughly 28.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:24 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $22.17 one way or $44.35 round trip. Estimated CO2 is about 52.3 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms then Chance Rain And Snow Showers around North La Crosse and Rain Likely near Greenville.
Stop Ideas Near Friendship
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Friendship.
Westfield, WI
Wisconsin Dells
Wisconsin Rapids, WI
Portage
Flight Path Map
This map shows the direct air route between North La Crosse and Greenville. Straight-line distance: 138.21 mi (222.42 km).
#1 North La Crosse
A city in La Crosse County, Wisconsin.
| Population | 50,470 |
| Coordinates | 43.8463500, -91.2481900 |
| Altitude | 197 |
| Country | United States |
#2 Greenville
Town in Outagamie County, Wisconsin, United States
| Population | 12,529 |
| Coordinates | 44.3002600, -88.5365000 |
| Altitude | 248 |
| Country | United States |
End: Greenville (-88.5365, 44.30026)
Estimated Travel Time
Distance: 268 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 32m |
| 40 mph (64.37 km/h) | 04h 09m |
| 50 mph (80.47 km/h) | 03h 19m |
| 60 mph (96.56 km/h) | 02h 46m |
| 70 mph (112.65 km/h) | 02h 22m |
| 80 mph (129 km/h) | 02h 04m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $22.17 | $44.35 |
| Mid-grade | $4.25 | $25.01 | $50.02 |
| Premium | $4.65 | $27.37 | $54.73 |
| Diesel | $5.30 | $31.19 | $62.38 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.