How far is Greenville, WI from La Crosse, WI?
The driving distance from Greenville, WI to La Crosse, WI is about 187.2 miles (301.3 km), with a travel time of about 03h 14m by car.
- The straight-line flight distance is about 138.6 miles (223 km).
- For a round trip, plan for roughly 06h 28m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 14m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Village in Adams County, Wisconsin
Route Weather Snapshot
Check the forecast at both ends before you head out.
Rain Likely
Chance Showers And Thunderstorms then Chance Rain And Snow Showers
Driving Route Map
The map below follows the saved road route between Greenville and La Crosse.
Turn-by-Turn Driving Directions
Step-by-step road directions between Greenville and La Crosse.
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1
Start on Greenville Drive
10 m · 3 sec · Greenville Drive
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2
Turn left onto Municipal Drive
1.4 km · 2 min · Municipal Drive
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3
Enter the roundabout and take exit 2 toward Municipal Drive
43 m · 3 sec · Municipal Drive
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4
Exit the roundabout onto Municipal Drive
1.6 km · 2 min · Municipal Drive
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5
Turn right onto Wisconsin Avenue
6.7 mi · 10 min · Wisconsin Avenue
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6
Continue on State Road 96
1.1 mi · 2 min · State Road 96
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7
Continue on Wisconsin Avenue
2.3 mi · 3 min · Wisconsin Avenue
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8
Enter the roundabout and take exit 2 toward State Highway 96
41 m · 8 sec · State Highway 96
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9
Exit the roundabout onto State Highway 96
1.8 mi · 3 min · State Highway 96
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10
Continue on State Road 96
3.9 mi · 5 min · State Road 96
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11
Continue on State Highway 110
3.2 mi · 5 min · State Highway 110
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12
Continue on State Highway 49
8.8 mi · 13 min · State Highway 49
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13
Turn right onto County Road M
2 mi · 5 min · County Road M
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14
Continue on County Road M
2674 ft · 1 min · County Road M
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15
Continue on County Road M
3 mi · 7 min · County Road M
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16
At the end of the road, turn right onto County Highway E
620 ft · 22 sec · County Highway E
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17
Turn left onto County Highway A
8.1 mi · 12 min · County Highway A
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18
At the end of the road, turn left onto State Highway 22
8.7 mi · 13 min · State Highway 22
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19
Turn right onto West Main Street
763 ft · 32 sec · West Main Street
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20
Turn left onto South Cambridge Street
1 km · 1 min · South Cambridge Street
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21
Turn right onto West Bird Avenue
785 ft · 40 sec · West Bird Avenue
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22
Turn left onto State Highway 21
12.3 mi · 17 min · State Highway 21
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23
Continue on Wautoma Road
2396 ft · 50 sec · Wautoma Road
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24
Continue on East Follett Drive
28.9 mi · 41 min · East Follett Drive
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25
Continue on East 3rd Street
10.9 mi · 16 min · East 3rd Street
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26
Continue on State Highway 21
11 mi · 15 min · State Highway 21
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27
Continue on East McCoy Boulevard
1684 ft · 34 sec · East McCoy Boulevard
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28
Continue on State Highway 21
640 ft · 12 sec · State Highway 21
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29
Take the exit straight
1644 ft · 42 sec
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30
Merge slight left
2.8 mi · 3 min
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31
Take the exit slight right toward I 90 West: La Crosse, Albert Lea
1.2 km · 51 sec
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32
Merge slight left
38.1 mi · 41 min
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33
Take the exit slight right toward WI 16: La Crosse, Onalaska
1636 ft · 42 sec
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34
At the end of the road, turn left
4.9 mi · 9 min
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35
Continue on Losey Boulevard North
2575 ft · 2 min · Losey Boulevard North
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36
Turn right onto Main Street
1.1 km · 2 min · Main Street
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37
Turn left onto 16th Street South
1.3 km · 2 min · 16th Street South
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38
Turn right onto Johnson Street
1824 ft · 1 min · Johnson Street
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39
At the end of the road, turn right onto West Avenue South
99 m · 11 sec · West Avenue South
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40
Arrive at your destination
0 m · 1 sec · West Avenue South
Car Route Details
A richer read on the saved driving route between Greenville and La Crosse.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
I 90 West
Merge slight left
38.1 mi · 00h 41m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Rain Likely leaving Greenville and Chance Showers And Thunderstorms then Chance Rain And Snow Showers near La Crosse.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Greenville to La Crosse?
The road trip is about 187.2 miles (301.3 km) and usually takes 03h 14m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Friendship is a useful midpoint, sitting about 83 miles from Greenville and 104.2 miles from La Crosse.
How much longer is the road route than the straight-line distance?
The direct path is about 138.6 miles (223 km), while the road route adds roughly 48.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:32 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $24.89 one way or $49.78 round trip. Estimated CO2 is about 58.7 kg one way.
What should you check before leaving?
Before you leave, expect Rain Likely around Greenville and Chance Showers And Thunderstorms then Chance Rain And Snow Showers near La Crosse.
Stop Ideas Near Friendship
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Friendship.
Westfield, WI
Wisconsin Dells
Wisconsin Rapids, WI
Portage
Flight Path Map
This map shows the direct air route between Greenville and La Crosse. Straight-line distance: 138.58 mi (223.02 km).
#1 Greenville
Town in Outagamie County, Wisconsin, United States
| Population | 12,529 |
| Coordinates | 44.3002600, -88.5365000 |
| Altitude | 248 |
| Country | United States |
#2 La Crosse
The most populous city in La Crosse County, Wisconsin.
| Population | 51,163 |
| Coordinates | 43.8013600, -91.2395800 |
| Altitude | 204 |
| Country | United States |
End: West Avenue South (-91.239623, 43.801338)
Estimated Travel Time
Distance: 301 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 06h 14m |
| 40 mph (64.37 km/h) | 04h 40m |
| 50 mph (80.47 km/h) | 03h 44m |
| 60 mph (96.56 km/h) | 03h 07m |
| 70 mph (112.65 km/h) | 02h 40m |
| 80 mph (129 km/h) | 02h 20m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $24.89 | $49.78 |
| Mid-grade | $4.25 | $28.07 | $56.14 |
| Premium | $4.65 | $30.72 | $61.43 |
| Diesel | $5.30 | $35.01 | $70.01 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Wisconsin · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.