How far is Cape Girardeau, MO from Nixa, MO?
The driving distance from Cape Girardeau, MO to Nixa, MO is about 270.7 miles (435.6 km), with a travel time of about 05h 22m by car.
- The straight-line flight distance is about 208.7 miles (335.8 km).
- For a round trip, plan for roughly 10h 45m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 22m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Cape Girardeau and Nixa.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Girardeau and Nixa.
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1
Start on Broadway Street
2497 ft · 56 sec · Broadway Street
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2
Turn left onto North Sprigg Street
1.2 km · 2 min · North Sprigg Street
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3
Turn right onto Shawnee Parkway
1.6 mi · 3 min · Shawnee Parkway
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4
Turn left onto South Kingshighway
1.9 mi · 3 min · South Kingshighway
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5
Keep slight left to continue on I 55 South, US 61 South: Sikeston
27.2 mi · 29 min
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6
Take the exit slight right toward US 60 West: Dexter, Poplar Bluff
2865 ft · 1 min
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7
Merge slight left
45.4 mi · 52 min
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8
Keep slight left
5.5 mi · 6 min
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9
Take the exit slight right toward US 60 West, US 67 North: Springfield, Saint Louis
4.5 mi · 6 min
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10
Take the exit slight right
172.8 mi · 3 hr 23 min
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11
Take the exit slight right toward US 65 South: Branson
927 ft · 40 sec
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12
Merge slight left onto Schoolcraft Freeway
2.5 mi · 3 min · Schoolcraft Freeway
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13
Continue on American Legion Memorial Highway
1.4 mi · 2 min · American Legion Memorial Highway
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14
Take the exit slight right toward MO J, MO CC: Fremont Hills
1112 ft · 27 sec
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15
Turn straight
1.4 km · 2 min
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16
Turn left onto Fremont Road
1.5 mi · 2 min · Fremont Road
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17
Turn right onto East North Road
1 mi · 2 min · East North Road
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18
Turn left onto North Cheyenne Road
3150 ft · 1 min · North Cheyenne Road
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19
At the end of the road, turn right
1.7 mi · 3 min
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20
Turn left
18 m · 4 sec
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21
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Cape Girardeau and Nixa.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 60 West
Take the exit slight right
173 mi · 03h 23m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Cape Girardeau and Mostly Sunny near Nixa.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Girardeau to Nixa?
The road trip is about 270.7 miles (435.6 km) and usually takes 05h 22m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Winona is a useful midpoint, sitting about 135.1 miles from Cape Girardeau and 135.5 miles from Nixa.
How much longer is the road route than the straight-line distance?
The direct path is about 208.7 miles (335.8 km), while the road route adds roughly 62 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:14 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.01 one way or $72.03 round trip. Estimated CO2 is about 84.9 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Cape Girardeau and Mostly Sunny near Nixa.
Stop Ideas Near Winona
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Winona.
Poplar Bluff
Walnut Ridge
Flight Path Map
This map shows the direct air route between Cape Girardeau and Nixa. Straight-line distance: 208.67 mi (335.82 km).
#1 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
#2 Nixa
City in Christian County, Missouri
| Population | 23,330 |
| Coordinates | 37.0433900, -93.2943500 |
| Altitude | 395 |
| Country | United States |
End: Nixa (-93.29435, 37.04339)
Estimated Travel Time
Distance: 436 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 01m |
| 40 mph (64.37 km/h) | 06h 46m |
| 50 mph (80.47 km/h) | 05h 24m |
| 60 mph (96.56 km/h) | 04h 30m |
| 70 mph (112.65 km/h) | 03h 52m |
| 80 mph (129 km/h) | 03h 22m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $36.01 | $72.03 |
| Mid-grade | $4.25 | $40.62 | $81.23 |
| Premium | $4.65 | $44.45 | $88.89 |
| Diesel | $5.30 | $50.65 | $101.31 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 25, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.