How far is Nixa, MO from Cape Girardeau, MO?
The driving distance from Nixa, MO to Cape Girardeau, MO is about 273.2 miles (439.7 km), with a travel time of about 04h 20m by car.
- The straight-line flight distance is about 208.7 miles (335.8 km).
- For a round trip, plan for roughly 08h 40m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 20m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Nixa and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Nixa and Cape Girardeau.
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1
Start on the route
18 m · 7 sec
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2
Turn right onto East Mount Vernon Street
1.7 mi · 3 min · East Mount Vernon Street
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3
Turn left onto North Cheyenne Road
3150 ft · 1 min · North Cheyenne Road
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4
Turn right onto East North Road
1 mi · 2 min · East North Road
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5
At the end of the road, turn left onto Fremont Road
1.5 mi · 3 min · Fremont Road
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6
Turn right
1.4 km · 2 min
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7
Turn straight
611 ft · 24 sec
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8
Take the ramp left toward US 65 North: Springfield
1043 ft · 26 sec
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9
Merge slight left onto American Legion Memorial Highway
1.4 mi · 2 min · American Legion Memorial Highway
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10
Continue on Schoolcraft Freeway
2.3 mi · 3 min · Schoolcraft Freeway
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11
Take the exit slight right toward US 60 East: Cabool
1498 ft · 32 sec
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12
Merge slight left
81.9 mi · 1 hr 36 min
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13
Keep slight left to continue on US 60 East: Mountain View, Poplar Bluff
90.4 mi · 1 hr 47 min
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14
Keep slight right
4.8 mi · 6 min
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15
Turn straight onto North Westwood Boulevard
823 ft · 14 sec · North Westwood Boulevard
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16
Turn slight left
84 m · 12 sec
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17
Turn left
756 ft · 16 sec
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18
Take the ramp right
1102 ft · 27 sec
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19
Merge slight left
51 mi · 59 min
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20
Take the exit slight right toward I 55 North: Saint Louis
1793 ft · 44 sec
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21
Merge slight left
27.4 mi · 29 min
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22
Keep slight right to continue on US 61, I 55 Business: Cape Girardeau
2 mi · 3 min
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23
Turn right onto Shawnee Parkway
1.6 mi · 3 min · Shawnee Parkway
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24
Turn left onto South Sprigg Street
1.3 km · 2 min · South Sprigg Street
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25
Turn right onto Broadway Street
2497 ft · 51 sec · Broadway Street
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26
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Nixa and Cape Girardeau.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 60 East
Keep slight left to continue on US 60 East: Mountain View, Poplar Bluff
90.4 mi · 01h 47m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Mostly Sunny leaving Nixa and Sunny near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Nixa to Cape Girardeau?
The road trip is about 273.2 miles (439.7 km) and usually takes 04h 20m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Winona is a useful midpoint, sitting about 135.4 miles from Nixa and 137.8 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 208.7 miles (335.8 km), while the road route adds roughly 64.5 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 8:20 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.35 one way or $72.70 round trip. Estimated CO2 is about 85.7 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Nixa and Sunny near Cape Girardeau.
Stop Ideas Near Winona
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Winona.
Poplar Bluff
Walnut Ridge
Flight Path Map
This map shows the direct air route between Nixa and Cape Girardeau. Straight-line distance: 208.67 mi (335.82 km).
#1 Nixa
City in Christian County, Missouri
| Population | 23,330 |
| Coordinates | 37.0433900, -93.2943500 |
| Altitude | 395 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 440 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 06m |
| 40 mph (64.37 km/h) | 06h 49m |
| 50 mph (80.47 km/h) | 05h 27m |
| 60 mph (96.56 km/h) | 04h 33m |
| 70 mph (112.65 km/h) | 03h 54m |
| 80 mph (129 km/h) | 03h 24m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $36.35 | $72.70 |
| Mid-grade | $4.25 | $41.00 | $82.00 |
| Premium | $4.65 | $44.86 | $89.73 |
| Diesel | $5.30 | $51.13 | $102.26 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 25, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.