How far is Cape Girardeau, MO from Des Peres, MO?
The driving distance from Cape Girardeau, MO to Des Peres, MO is about 113.6 miles (182.9 km), with a travel time of about 02h 09m by car.
- The straight-line flight distance is about 102.4 miles (164.8 km).
- For a round trip, plan for roughly 04h 18m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 09m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in and the county seat of Ste.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Sunny
Mostly Cloudy then Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Cape Girardeau and Des Peres.
Turn-by-Turn Driving Directions
Step-by-step road directions between Cape Girardeau and Des Peres.
-
1
Start on Broadway Street
2 mi · 4 min · Broadway Street
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2
Turn right onto North Kingshighway
3.6 mi · 6 min · North Kingshighway
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3
Take the ramp slight right toward I 55 North: Saint Louis
1606 ft · 39 sec
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4
Merge slight left
95.1 mi · 1 hr 42 min
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5
Continue on Rosa Parks Highway
1.3 mi · 2 min · Rosa Parks Highway
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6
Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago
1279 ft · 27 sec
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7
Keep slight left to continue on I 270 West: Kansas City
118 m · 8 sec
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8
Continue on I 270 West
1.2 km · 1 min
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9
Merge slight left
9 mi · 11 min
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10
Take the exit slight right toward MO 100: Manchester Road, West County Center Drive, Lewis-Clark Trail
1248 ft · 27 sec
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11
Continue on MO 100: Manchester Road
117 m · 8 sec
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12
Keep slight right to continue on MO 100 East: Manchester Road
68 m · 5 sec
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13
Turn straight onto Manchester Road
1.4 km · 2 min · Manchester Road
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14
Arrive at your destination
0 m · 1 sec · Manchester Road
Car Route Details
A richer read on the saved driving route between Cape Girardeau and Des Peres.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 55 North
Merge slight left
95.1 mi · 01h 42m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Mostly Sunny leaving Cape Girardeau and Mostly Cloudy then Chance Rain Showers near Des Peres.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Cape Girardeau to Des Peres?
The road trip is about 113.6 miles (182.9 km) and usually takes 02h 09m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Sainte Genevieve is a useful midpoint, sitting about 56.9 miles from Cape Girardeau and 56.8 miles from Des Peres.
How much longer is the road route than the straight-line distance?
The direct path is about 102.4 miles (164.8 km), while the road route adds roughly 11.2 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:12 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.12 one way or $30.24 round trip. Estimated CO2 is about 35.6 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Cape Girardeau and Mostly Cloudy then Chance Rain Showers near Des Peres.
Stop Ideas Near Sainte Genevieve
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sainte Genevieve.
Du Quoin
Gateway Transportation Center
Kirkwood
Carbondale station
Flight Path Map
This map shows the direct air route between Cape Girardeau and Des Peres. Straight-line distance: 102.42 mi (164.83 km).
#1 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
#2 Des Peres
City in Saint Louis County, Missouri, United States
| Population | 8,724 |
| Coordinates | 38.6008900, -90.4329000 |
| Altitude | 186 |
| Country | United States |
End: Des Peres (-90.4329, 38.60089)
Estimated Travel Time
Distance: 183 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 47m |
| 40 mph (64.37 km/h) | 02h 50m |
| 50 mph (80.47 km/h) | 02h 16m |
| 60 mph (96.56 km/h) | 01h 53m |
| 70 mph (112.65 km/h) | 01h 37m |
| 80 mph (129 km/h) | 01h 25m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $15.12 | $30.24 |
| Mid-grade | $4.25 | $17.05 | $34.11 |
| Premium | $4.65 | $18.66 | $37.33 |
| Diesel | $5.30 | $21.27 | $42.54 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 12, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.