How far is Des Peres, MO from Cape Girardeau, MO?
The driving distance from Des Peres, MO to Cape Girardeau, MO is about 117.2 miles (188.6 km), with a travel time of about 01h 51m by car.
- The straight-line flight distance is about 102.4 miles (164.8 km).
- For a round trip, plan for roughly 03h 42m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 01h 51m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
This departure sits inside the recommended comfort window for the route.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in and the county seat of Ste.
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Des Peres and Cape Girardeau.
Turn-by-Turn Driving Directions
Step-by-step road directions between Des Peres and Cape Girardeau.
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1
Start on Manchester Road
1.3 km · 1 min · Manchester Road
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2
Take the ramp slight left toward I 270 South
2176 ft · 1 min
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3
Merge slight left
9.3 mi · 12 min
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4
Take the exit slight right toward I 55, US 61, US 67: Saint Louis, Memphis, Lemay Ferry Road
1911 ft · 27 sec
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5
Keep slight right to continue on I 55 South: Memphis
2031 ft · 44 sec
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6
Merge slight left onto Rosa Parks Highway
1.5 mi · 2 min · Rosa Parks Highway
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7
Continue on Officer Thomas G. Smith, Jr. Memorial Highway
1.8 mi · 2 min · Officer Thomas G. Smith, Jr. Memorial Highway
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8
Continue on Police Officer Steven Jarvis Memorial Highway
93.1 mi · 1 hr 40 min · Police Officer Steven Jarvis Memorial Highway
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9
Take the exit slight right toward US 61, MO 34, I 55 Business: Cape Girardeau, Jackson
814 ft · 17 sec
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10
Keep slight left to continue on I 55 Business, US 61 South, MO 34 East: Cape Girardeau
1354 ft · 29 sec
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11
Continue on North Kingshighway
3.6 mi · 6 min · North Kingshighway
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12
Turn left onto Broadway Street
2 mi · 4 min · Broadway Street
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13
Arrive at your destination
0 m · 1 sec · Broadway Street
Car Route Details
A richer read on the saved driving route between Des Peres and Cape Girardeau.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Police Officer Steven Jarvis Memorial Highway
Continue on Police Officer Steven Jarvis Memorial Highway
93.1 mi · 01h 40m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Sunny leaving Des Peres and Sunny near Cape Girardeau.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Des Peres to Cape Girardeau?
The road trip is about 117.2 miles (188.6 km) and usually takes 01h 51m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
Sainte Genevieve is a useful midpoint, sitting about 56.9 miles from Des Peres and 60.3 miles from Cape Girardeau.
How much longer is the road route than the straight-line distance?
The direct path is about 102.4 miles (164.8 km), while the road route adds roughly 14.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 2:48 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $15.61 one way or $31.22 round trip. Estimated CO2 is about 36.8 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Des Peres and Sunny near Cape Girardeau.
Stop Ideas Near Sainte Genevieve
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Sainte Genevieve.
Du Quoin
Gateway Transportation Center
Kirkwood
Carbondale station
Flight Path Map
This map shows the direct air route between Des Peres and Cape Girardeau. Straight-line distance: 102.42 mi (164.83 km).
#1 Des Peres
City in Saint Louis County, Missouri, United States
| Population | 8,724 |
| Coordinates | 38.6008900, -90.4329000 |
| Altitude | 186 |
| Country | United States |
#2 Cape Girardeau
The second-largest city in Cape Girardeau County, Missouri.
| Population | 41,588 |
| Coordinates | 37.3058800, -89.5181500 |
| Altitude | 108 |
| Country | United States |
End: Broadway Street (-89.518146, 37.305904)
Estimated Travel Time
Distance: 189 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 03h 54m |
| 40 mph (64.37 km/h) | 02h 55m |
| 50 mph (80.47 km/h) | 02h 20m |
| 60 mph (96.56 km/h) | 01h 57m |
| 70 mph (112.65 km/h) | 01h 40m |
| 80 mph (129 km/h) | 01h 27m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $15.61 | $31.22 |
| Mid-grade | $4.25 | $17.61 | $35.21 |
| Premium | $4.65 | $19.27 | $38.54 |
| Diesel | $5.30 | $21.96 | $43.92 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.