How far is Tampa, FL from Panama City, FL?
The driving distance from Tampa, FL to Panama City, FL is about 375.4 miles (604.1 km), with a travel time of about 07h 10m by car.
- The straight-line flight distance is about 246.4 miles (396.6 km).
- For a round trip, plan for roughly 14h 21m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 10m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
County seat of Suwannee County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Tampa and Panama City.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tampa and Panama City.
-
1
Start on East Kennedy Boulevard
122 m · 17 sec · East Kennedy Boulevard
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2
Turn right onto North Ashley Drive
1748 ft · 49 sec · North Ashley Drive
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3
Take the ramp straight toward I 275
1164 ft · 29 sec
-
4
Keep slight right to continue on I 275 North
843 ft · 21 sec
-
5
Merge slight left
17 mi · 21 min
-
6
Merge slight left
160.3 mi · 2 hr 52 min
-
7
Take the exit slight right toward I 10: Jacksonville, Tallahassee
820 ft · 16 sec
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8
Keep slight left to continue on I 10 West: Tallahassee
1569 ft · 30 sec
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9
Merge slight right
121.8 mi · 2 hr 11 min
-
10
Take the exit slight right toward FL 12: Gretna, Greensboro
1341 ft · 46 sec
-
11
Keep slight left to continue on FL `12 South: Greensboro
112 m · 11 sec
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12
Turn straight onto Greensboro Highway
2.4 mi · 4 min · Greensboro Highway
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13
Continue on Selman Street
3018 ft · 1 min · Selman Street
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14
Turn left onto Green Avenue
2342 ft · 57 sec · Green Avenue
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15
Continue on Bristol Highway
17.7 mi · 23 min · Bristol Highway
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16
At the end of the road, turn right
28.4 mi · 39 min
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17
Turn left
24.1 mi · 32 min
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18
Turn left onto Harrison Avenue
1 mi · 3 min · Harrison Avenue
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19
Turn left onto East 7th Street
69 m · 12 sec · East 7th Street
-
20
Turn right onto Luverne Avenue
131 m · 19 sec · Luverne Avenue
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21
Arrive at your destination
0 m · 1 sec · Luverne Avenue
Car Route Details
A richer read on the saved driving route between Tampa and Panama City.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 275 North
Merge slight left
160 mi · 02h 52m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Sunny leaving Tampa and Sunny near Panama City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tampa to Panama City?
The road trip is about 375.4 miles (604.1 km) and usually takes 07h 10m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Live Oak is a useful midpoint, sitting about 187.8 miles from Tampa and 187.6 miles from Panama City.
How much longer is the road route than the straight-line distance?
The direct path is about 246.4 miles (396.6 km), while the road route adds roughly 129 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $54.96 one way or $109.92 round trip. Estimated CO2 is about 117.8 kg one way.
Do you cross a time zone on this route?
Yes. There is about a 1 hour time difference between Tampa and Panama City, so arrival and return times should be read in local time.
What should you check before leaving?
Before you leave, expect Sunny around Tampa and Sunny near Panama City.
Stop Ideas Near Live Oak
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Live Oak.
Gainesville, Florida
Waldo, Florida
Flight Path Map
This map shows the direct air route between Tampa and Panama City. Straight-line distance: 246.44 mi (396.61 km).
#1 Tampa
The third most populous city in Florida and the center of the Tampa metropolitan area.
| Population | 407,599 |
| Coordinates | 27.9475200, -82.4584300 |
| Altitude | 1 |
| Country | United States |
#2 Panama City
County seat of Bay County, Florida, United States
| Population | 34,667 |
| Coordinates | 30.1594600, -85.6598300 |
| Altitude | 8 |
| Country | United States |
End: Panama City (-85.65983, 30.15946)
Estimated Travel Time
Distance: 604 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 12h 30m |
| 40 mph (64.37 km/h) | 09h 23m |
| 50 mph (80.47 km/h) | 07h 30m |
| 60 mph (96.56 km/h) | 06h 15m |
| 70 mph (112.65 km/h) | 05h 21m |
| 80 mph (129 km/h) | 04h 40m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $54.96 | $109.92 |
| Mid-grade | $4.60 | $60.90 | $121.79 |
| Premium | $4.90 | $64.87 | $129.74 |
| Diesel | $4.35 | $57.64 | $115.27 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 17, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.