How far is Tampa, FL from Big Pine Key, FL?
The driving distance from Tampa, FL to Big Pine Key, FL is about 391.2 miles (629.6 km), with a travel time of about 07h 53m by car.
- The straight-line flight distance is about 236.6 miles (380.7 km).
- For a round trip, plan for roughly 15h 47m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 53m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Collier County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Slight Chance Rain Showers
Driving Route Map
The map below follows the saved road route between Tampa and Big Pine Key.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tampa and Big Pine Key.
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1
Start on East Kennedy Boulevard
36 m · 11 sec · East Kennedy Boulevard
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2
Turn left onto North Tampa Street
90 m · 13 sec · North Tampa Street
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3
Turn left onto East Jackson Street
2823 ft · 2 min · East Jackson Street
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4
Keep slight left to continue on East Jackson Street
21 m · 4 sec · East Jackson Street
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5
Turn left onto North Nebraska Avenue
123 m · 10 sec · North Nebraska Avenue
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6
Take the ramp slight right toward FL 618 Toll East: Brandon
853 ft · 21 sec
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7
Merge slight left onto Lee Roy Selmon Expressway
7.8 mi · 9 min · Lee Roy Selmon Expressway
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8
Keep slight right to continue on I 75 South: Naples
2585 ft · 34 sec
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9
Merge slight left
55.8 mi · 1 hr
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10
Keep slight left
175.7 mi · 3 hr 8 min
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11
Take the exit slight right toward US 27: Miami, South Bay
1118 ft · 21 sec
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12
Keep slight right to continue on US 27 South: Miami
2407 ft · 59 sec
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13
Merge slight left
9.2 mi · 11 min
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14
Keep slight right
8.6 mi · 11 min
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15
Take the exit right toward Florida's Turnpike South: Homestead, Key West
1324 ft · 32 sec
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16
Merge slight left onto Homestead Extension of Florida's Turnpike
34.5 mi · 41 min · Homestead Extension of Florida's Turnpike
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17
Keep slight left
2930 ft · 1 min
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18
Merge slight left onto Dixie Highway
19.2 mi · 27 min · Dixie Highway
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19
Continue on Overseas Highway
77.4 mi · 2 hr · Overseas Highway
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20
Arrive at your destination
0 m · 1 sec · Overseas Highway
Car Route Details
A richer read on the saved driving route between Tampa and Big Pine Key.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
I 75 South
Keep slight left
176 mi · 03h 08m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Sunny leaving Tampa and Slight Chance Rain Showers near Big Pine Key.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tampa to Big Pine Key?
The road trip is about 391.2 miles (629.6 km) and usually takes 07h 53m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Immokalee is a useful midpoint, sitting about 195.8 miles from Tampa and 195.4 miles from Big Pine Key.
How much longer is the road route than the straight-line distance?
The direct path is about 236.6 miles (380.7 km), while the road route adds roughly 154.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $57.28 one way or $114.57 round trip. Estimated CO2 is about 122.7 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Sunny around Tampa and Slight Chance Rain Showers near Big Pine Key.
Stop Ideas Near Immokalee
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Immokalee.
Fort Myers, Florida
Port Charlotte, Florida
Okeechobee
Flight Path Map
This map shows the direct air route between Tampa and Big Pine Key. Straight-line distance: 236.56 mi (380.71 km).
#1 Tampa
The third most populous city in Florida and the center of the Tampa metropolitan area.
| Population | 407,599 |
| Coordinates | 27.9475200, -82.4584300 |
| Altitude | 1 |
| Country | United States |
#2 Big Pine Key
Census designated place
| Population | 4,252 |
| Coordinates | 24.6698700, -81.3539700 |
| Altitude | 1 |
| Country | United States |
End: Big Pine Key (-81.35397, 24.66987)
Estimated Travel Time
Distance: 630 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 02m |
| 40 mph (64.37 km/h) | 09h 46m |
| 50 mph (80.47 km/h) | 07h 49m |
| 60 mph (96.56 km/h) | 06h 31m |
| 70 mph (112.65 km/h) | 05h 35m |
| 80 mph (129 km/h) | 04h 52m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $57.28 | $114.57 |
| Mid-grade | $4.60 | $63.47 | $126.94 |
| Premium | $4.90 | $67.61 | $135.23 |
| Diesel | $4.35 | $60.07 | $120.15 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.