How far is Tallahassee, FL from Saint Leo, FL?
The driving distance from Tallahassee, FL to Saint Leo, FL is about 249.9 miles (402.1 km), with a travel time of about 04h 39m by car.
- The straight-line flight distance is about 189.5 miles (304.9 km).
- For a round trip, plan for roughly 09h 19m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 39m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Alachua County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Mostly Sunny
Driving Route Map
The map below follows the saved road route between Tallahassee and Saint Leo.
Turn-by-Turn Driving Directions
Step-by-step road directions between Tallahassee and Saint Leo.
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1
Start on South Monroe Street
55 m · 8 sec · South Monroe Street
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2
Turn right onto East Pensacola Street
1428 ft · 47 sec · East Pensacola Street
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3
Turn left onto South Franklin Boulevard
2557 ft · 1 min · South Franklin Boulevard
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4
Turn right onto East Tennessee Street
3230 ft · 1 min · East Tennessee Street
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5
Continue on Mahan Drive
6.5 mi · 12 min · Mahan Drive
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6
Take the ramp slight right toward I 10 East: Lake City
1.1 km · 1 min
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7
Merge slight left
86.9 mi · 1 hr 33 min
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8
Take the exit slight right toward I-75 South: Tampa
1959 ft · 37 sec
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9
Merge slight left
148.7 mi · 2 hr 39 min
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10
Take the exit slight right toward FL 52: Dade City, New Port Richey
2644 ft · 1 min
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11
Turn slight left onto State Road 52
1.4 mi · 3 min · State Road 52
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12
Turn slight left
103 m · 14 sec
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13
Continue on Old State Road 52
2.3 mi · 4 min · Old State Road 52
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14
Enter the roundabout and take exit 1 toward Old State Road 52
10 m · 1 sec · Old State Road 52
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15
Exit the roundabout onto Old State Road 52
1.3 km · 1 min · Old State Road 52
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16
Turn left
94 m · 24 sec
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17
Enter the roundabout and take exit 2 toward the route
73 m · 19 sec
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18
Exit the roundabout
64 m · 16 sec
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19
Turn right
85 m · 21 sec
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20
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Tallahassee and Saint Leo.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I-75 South
Merge slight left
149 mi · 02h 39m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Tallahassee and Mostly Sunny near Saint Leo.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Tallahassee to Saint Leo?
The road trip is about 249.9 miles (402.1 km) and usually takes 04h 39m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
High Springs is a useful midpoint, sitting about 125 miles from Tallahassee and 124.8 miles from Saint Leo.
How much longer is the road route than the straight-line distance?
The direct path is about 189.5 miles (304.9 km), while the road route adds roughly 60.4 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 7:40 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.59 one way or $73.17 round trip. Estimated CO2 is about 78.4 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Tallahassee and Mostly Sunny near Saint Leo.
Stop Ideas Near High Springs
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to High Springs.
Gainesville, Florida
Waldo, Florida
Ocala, Florida
Palatka
Flight Path Map
This map shows the direct air route between Tallahassee and Saint Leo. Straight-line distance: 189.45 mi (304.89 km).
#1 Tallahassee
The capital of Florida.
| Population | 196,326 |
| Coordinates | 30.4382600, -84.2807300 |
| Altitude | 62 |
| Country | United States |
#2 Saint Leo
Town of the United States
| Population | 1,372 |
| Coordinates | 28.3372300, -82.2584200 |
| Altitude | 57 |
| Country | United States |
End: Saint Leo (-82.25842, 28.33723)
Estimated Travel Time
Distance: 402 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 08h 19m |
| 40 mph (64.37 km/h) | 06h 14m |
| 50 mph (80.47 km/h) | 04h 59m |
| 60 mph (96.56 km/h) | 04h 09m |
| 70 mph (112.65 km/h) | 03h 34m |
| 80 mph (129 km/h) | 03h 07m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $36.59 | $73.17 |
| Mid-grade | $4.60 | $40.54 | $81.07 |
| Premium | $4.90 | $43.18 | $86.37 |
| Diesel | $4.35 | $38.37 | $76.73 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.