How far is St. Louis, MO from Mount Pleasant, MO?
The driving distance from St. Louis, MO to Mount Pleasant, MO is about 158.6 miles (255.2 km), with a travel time of about 03h 09m by car.
- The straight-line flight distance is about 127 miles (204.4 km).
- For a round trip, plan for roughly 06h 19m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 09m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between St. Louis and Mount Pleasant.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Mount Pleasant.
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1
Start on Market Street
1.6 mi · 3 min · Market Street
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2
Take the ramp slight left toward I 64 West, US 40 West: Wentzville
1531 ft · 24 sec
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3
Merge slight left onto Jack Buck Memorial Highway
4.3 mi · 6 min · Jack Buck Memorial Highway
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4
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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5
Continue on Avenue of the Saints
27.8 mi · 34 min · Avenue of the Saints
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6
Take the exit slight left toward I 70 West, US 40 West: Kansas City
3047 ft · 1 min
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7
Merge slight left onto Dwight D Eisenhower Highway
61.6 mi · 1 hr 11 min · Dwight D Eisenhower Highway
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8
Take the exit slight right toward US 54: Auxvasse, Mexico, Fulton
1196 ft · 28 sec
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9
Turn left
55.2 mi · 1 hr 2 min
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10
Turn left onto County Road 54-66
52 m · 7 sec · County Road 54-66
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11
Continue on Storage Road
657 ft · 31 sec · Storage Road
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12
Turn right onto Oakwood Road
1320 ft · 58 sec · Oakwood Road
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13
Continue on Oakwood Road
2514 ft · 2 min · Oakwood Road
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14
Turn right onto Old 54
679 ft · 30 sec · Old 54
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15
Continue on Doyle Road
1459 ft · 1 min · Doyle Road
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16
Arrive at your destination
0 m · 1 sec · Doyle Road
Car Route Details
A richer read on the saved driving route between St. Louis and Mount Pleasant.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Dwight D Eisenhower Highway
Merge slight left onto Dwight D Eisenhower Highway
61.6 mi · 01h 11m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving St. Louis and Showers And Thunderstorms near Mount Pleasant.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Mount Pleasant?
The road trip is about 158.6 miles (255.2 km) and usually takes 03h 09m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
New Florence is a useful midpoint, sitting about 79.2 miles from St. Louis and 79.4 miles from Mount Pleasant.
How much longer is the road route than the straight-line distance?
The direct path is about 127 miles (204.4 km), while the road route adds roughly 31.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 10:40 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.12 one way or $42.24 round trip. Estimated CO2 is about 49.8 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around St. Louis and Showers And Thunderstorms near Mount Pleasant.
Stop Ideas Near New Florence
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to New Florence.
Hermann
Washington
Jefferson City
Kirkwood
Flight Path Map
This map shows the direct air route between St. Louis and Mount Pleasant. Straight-line distance: 127.02 mi (204.42 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Mount Pleasant
Unincorporated community in Missouri
| Population | 4,830 |
| Coordinates | 38.3680900, -92.5235200 |
| Altitude | 282 |
| Country | United States |
End: Mount Pleasant (-92.52352, 38.36809)
Estimated Travel Time
Distance: 255 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 17m |
| 40 mph (64.37 km/h) | 03h 57m |
| 50 mph (80.47 km/h) | 03h 10m |
| 60 mph (96.56 km/h) | 02h 38m |
| 70 mph (112.65 km/h) | 02h 15m |
| 80 mph (129 km/h) | 01h 58m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $21.12 | $42.24 |
| Mid-grade | $4.25 | $23.82 | $47.63 |
| Premium | $4.65 | $26.06 | $52.12 |
| Diesel | $5.30 | $29.70 | $59.40 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.