How far is Mount Pleasant, MO from St. Louis, MO?
The driving distance from Mount Pleasant, MO to St. Louis, MO is about 158.6 miles (255.2 km), with a travel time of about 02h 28m by car.
- The straight-line flight distance is about 127 miles (204.4 km).
- For a round trip, plan for roughly 04h 57m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 8:00 AM to 10:00 AM CDT.
Reverse, save, or send this route
This route works well as a day trip with time at the destination. Copy the route link, send it to another device, or print a clean version before you head out.
This route works well as a day trip with time at the destination.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 02h 28m.
A morning start gives you useful time at the destination and keeps the return out of the late evening.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms
Showers And Thunderstorms Likely
Driving Route Map
The map below follows the saved road route between Mount Pleasant and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Mount Pleasant and St. Louis.
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1
Start on Doyle Road
82 m · 18 sec · Doyle Road
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2
Turn left
118 m · 14 sec
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3
Turn right
56 mi · 1 hr 3 min
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4
Take the exit slight right toward I 70 East, US 40 East: Saint Louis
1220 ft · 15 sec
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5
Merge slight left onto Dwight D. Eisenhower Highway
61.9 mi · 1 hr 11 min · Dwight D. Eisenhower Highway
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6
Take the exit slight right toward I 64 East, US 40 East, US 61 South: Chesterfield
1567 ft · 33 sec
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7
Merge slight left onto Avenue of the Saints
27.7 mi · 34 min · Avenue of the Saints
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8
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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9
Continue on Jack Buck Memorial Highway
5.8 mi · 7 min · Jack Buck Memorial Highway
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10
Take the exit slight right toward 14th Street
1115 ft · 34 sec
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11
Turn left onto South 14th Street
1715 ft · 42 sec · South 14th Street
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12
Turn right onto Market Street
956 ft · 27 sec · Market Street
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13
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Mount Pleasant and St. Louis.
Interchange-aware route
The drive includes several ramps, exits, or merges, so checking the next few maneuvers before busy interchanges is useful.
Dwight D. Eisenhower Highway
Merge slight left onto Dwight D. Eisenhower Highway
61.9 mi · 01h 11m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A comfortable day-trip route
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
Showers And Thunderstorms leaving Mount Pleasant and Showers And Thunderstorms Likely near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Mount Pleasant to St. Louis?
The road trip is about 158.6 miles (255.2 km) and usually takes 02h 28m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route works well as a day trip. You can leave in the morning, spend meaningful time at the destination, and still return the same day.
What is the halfway point on this route?
New Florence is a useful midpoint, sitting about 79.1 miles from Mount Pleasant and 79.4 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 127 miles (204.4 km), while the road route adds roughly 31.6 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 8:00 AM to 10:00 AM CDT. If you want a more comfortable same-day return, try to leave by 1:32 PM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $21.12 one way or $42.24 round trip. Estimated CO2 is about 49.8 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms around Mount Pleasant and Showers And Thunderstorms Likely near St. Louis.
Stop Ideas Near New Florence
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to New Florence.
Hermann
Washington
Jefferson City
Kirkwood
Flight Path Map
This map shows the direct air route between Mount Pleasant and St. Louis. Straight-line distance: 127.02 mi (204.42 km).
#1 Mount Pleasant
Unincorporated community in Missouri
| Population | 4,830 |
| Coordinates | 38.3680900, -92.5235200 |
| Altitude | 282 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 255 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 16m |
| 40 mph (64.37 km/h) | 03h 57m |
| 50 mph (80.47 km/h) | 03h 10m |
| 60 mph (96.56 km/h) | 02h 38m |
| 70 mph (112.65 km/h) | 02h 15m |
| 80 mph (129 km/h) | 01h 58m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $21.12 | $42.24 |
| Mid-grade | $4.25 | $23.82 | $47.63 |
| Premium | $4.65 | $26.06 | $52.12 |
| Diesel | $5.30 | $29.70 | $59.40 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 19, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.