How far is St. Louis, MO from Mound City, MO?
The driving distance from St. Louis, MO to Mound City, MO is about 340.3 miles (547.6 km), with a travel time of about 06h 26m by car.
- The straight-line flight distance is about 288.2 miles (463.8 km).
- For a round trip, plan for roughly 12h 53m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 06h 26m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Saline County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Isolated Showers And Thunderstorms
Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between St. Louis and Mound City.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Mound City.
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1
Start on Market Street
1.6 mi · 3 min · Market Street
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2
Take the ramp slight left toward I 64 West, US 40 West: Wentzville
1531 ft · 24 sec
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3
Merge slight left onto Jack Buck Memorial Highway
4.3 mi · 6 min · Jack Buck Memorial Highway
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4
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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5
Continue on Avenue of the Saints
27.8 mi · 34 min · Avenue of the Saints
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6
Take the exit slight left toward I 70 West, US 40 West: Kansas City
3047 ft · 1 min
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7
Merge slight left onto Dwight D Eisenhower Highway
80.7 mi · 1 hr 35 min · Dwight D Eisenhower Highway
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8
Continue on Sheriff Roger I. Wilson Memorial Highway
2 mi · 2 min · Sheriff Roger I. Wilson Memorial Highway
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9
Continue on Highway Patrol Sgt. Benjamin Booth Memorial Highway
1.6 mi · 2 min · Highway Patrol Sgt. Benjamin Booth Memorial Highway
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10
Continue on Dwight D. Eisenhower Highway
1.8 mi · 2 min · Dwight D. Eisenhower Highway
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11
Continue on U.S. Submarine Veterans' Memorial Highway
54.4 mi · 58 min · U.S. Submarine Veterans' Memorial Highway
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12
Continue on Dwight D. Eisenhower Highway
52.5 mi · 57 min · Dwight D. Eisenhower Highway
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13
Continue on Truman/Eisenhower Presidential Highway
2.7 mi · 3 min · Truman/Eisenhower Presidential Highway
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14
Continue on Clifton J. Scott Memorial Highway
1.8 mi · 2 min · Clifton J. Scott Memorial Highway
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15
Continue on Truman/Eisenhower Presidential Highway
2.9 mi · 3 min · Truman/Eisenhower Presidential Highway
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16
Continue on George Brett Super Highway
1.4 km · 58 sec · George Brett Super Highway
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17
Take the exit slight right toward I 435 North, US 24 East: Des Moines
1.1 mi · 2 min
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18
Merge slight left onto Lamar Hunt Memorial Highway
7.8 mi · 9 min · Lamar Hunt Memorial Highway
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19
Continue on I435 N
1.3 mi · 1 min · I435 N
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20
Continue straight
20.9 mi · 22 min
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21
Keep slight left to continue on I 29 North, US 71 North: Saint Joseph
37.1 mi · 40 min
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22
Continue straight
30 mi · 32 min
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23
Take the exit slight right toward MO 118: Mound City
1040 ft · 20 sec
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24
Turn right
903 ft · 21 sec
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25
Turn right onto State Street
1294 ft · 49 sec · State Street
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26
Turn left
30 m · 7 sec
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27
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between St. Louis and Mound City.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Dwight D Eisenhower Highway
Merge slight left onto Dwight D Eisenhower Highway
80.7 mi · 01h 35m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Isolated Showers And Thunderstorms leaving St. Louis and Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms near Mound City.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Mound City?
The road trip is about 340.3 miles (547.6 km) and usually takes 06h 26m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Nelson is a useful midpoint, sitting about 169.9 miles from St. Louis and 170.4 miles from Mound City.
How much longer is the road route than the straight-line distance?
The direct path is about 288.2 miles (463.8 km), while the road route adds roughly 52.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM CDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $45.29 one way or $90.58 round trip. Estimated CO2 is about 106.7 kg one way.
What should you check before leaving?
Before you leave, expect Isolated Showers And Thunderstorms around St. Louis and Slight Chance Showers And Thunderstorms then Chance Showers And Thunderstorms near Mound City.
Stop Ideas Near Nelson
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Nelson.
Sedalia
Warrensburg
Jefferson City
Lee's Summit
Flight Path Map
This map shows the direct air route between St. Louis and Mound City. Straight-line distance: 288.16 mi (463.75 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Mound City
City in Missouri
| Population | 1,039 |
| Coordinates | 40.1311100, -95.2316400 |
| Altitude | 271 |
| Country | United States |
End: Mound City (-95.23164, 40.13111)
Estimated Travel Time
Distance: 548 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 11h 20m |
| 40 mph (64.37 km/h) | 08h 30m |
| 50 mph (80.47 km/h) | 06h 48m |
| 60 mph (96.56 km/h) | 05h 40m |
| 70 mph (112.65 km/h) | 04h 51m |
| 80 mph (129 km/h) | 04h 14m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $45.29 | $90.58 |
| Mid-grade | $4.25 | $51.08 | $102.16 |
| Premium | $4.65 | $55.89 | $111.79 |
| Diesel | $5.30 | $63.70 | $127.40 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 16, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.