How far is St. Louis, MO from Doniphan, MO?
The driving distance from St. Louis, MO to Doniphan, MO is about 177.1 miles (285 km), with a travel time of about 03h 33m by car.
- The straight-line flight distance is about 142.8 miles (229.8 km).
- For a round trip, plan for roughly 07h 06m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 33m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Madison County, Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Showers And Thunderstorms Likely
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between St. Louis and Doniphan.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Doniphan.
-
1
Start on Market Street
26 m · 4 sec · Market Street
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2
Turn left onto South Tucker Boulevard
1.3 mi · 4 min · South Tucker Boulevard
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3
Turn straight onto Gravois Avenue
1619 ft · 46 sec · Gravois Avenue
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4
Take the ramp left toward I 55 South: Memphis
626 ft · 15 sec
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5
Merge slight left
32.7 mi · 38 min
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6
Take the exit slight right toward US 67 South: Farmington, Poplar Bluff
914 ft · 20 sec
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7
Keep slight left
729 ft · 18 sec
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8
Enter the roundabout and take exit 1 toward the route
9 m · 1 sec
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9
Exit the roundabout
112.6 mi · 2 hr 10 min
-
10
Take the exit slight right toward US 67 South: Corning, Arkansas
10.4 mi · 12 min
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11
Take the exit slight right
1651 ft · 45 sec
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12
Continue straight
18.2 mi · 27 min
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13
Turn left onto Walnut Street
1.1 km · 1 min · Walnut Street
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14
Turn left onto Plum Street
52 m · 7 sec · Plum Street
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15
Arrive at your destination
0 m · 1 sec · Plum Street
Car Route Details
A richer read on the saved driving route between St. Louis and Doniphan.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
US 67 South
Exit the roundabout
113 mi · 02h 10m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Showers And Thunderstorms Likely leaving St. Louis and Chance Showers And Thunderstorms near Doniphan.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Doniphan?
The road trip is about 177.1 miles (285 km) and usually takes 03h 33m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Cobalt Village is a useful midpoint, sitting about 88.6 miles from St. Louis and 88.5 miles from Doniphan.
How much longer is the road route than the straight-line distance?
The direct path is about 142.8 miles (229.8 km), while the road route adds roughly 34.3 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 9:54 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $23.57 one way or $47.14 round trip. Estimated CO2 is about 55.5 kg one way.
What should you check before leaving?
Before you leave, expect Showers And Thunderstorms Likely around St. Louis and Chance Showers And Thunderstorms near Doniphan.
Stop Ideas Near Cobalt Village
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Cobalt Village.
Poplar Bluff
Carbondale station
Du Quoin
Kirkwood
Flight Path Map
This map shows the direct air route between St. Louis and Doniphan. Straight-line distance: 142.79 mi (229.8 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Doniphan
City in Ripley County, Missouri, United States
| Population | 1,919 |
| Coordinates | 36.6208900, -90.8234600 |
| Altitude | 122 |
| Country | United States |
End: Doniphan (-90.82346, 36.62089)
Estimated Travel Time
Distance: 285 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 05h 54m |
| 40 mph (64.37 km/h) | 04h 25m |
| 50 mph (80.47 km/h) | 03h 32m |
| 60 mph (96.56 km/h) | 02h 57m |
| 70 mph (112.65 km/h) | 02h 31m |
| 80 mph (129 km/h) | 02h 12m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $23.57 | $47.14 |
| Mid-grade | $4.25 | $26.58 | $53.16 |
| Premium | $4.65 | $29.09 | $58.18 |
| Diesel | $5.30 | $33.15 | $66.30 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 18, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.