How far is St. Louis, MO from Cameron, MO?
The driving distance from St. Louis, MO to Cameron, MO is about 272.8 miles (439 km), with a travel time of about 05h 26m by car.
- The straight-line flight distance is about 229.8 miles (369.8 km).
- For a round trip, plan for roughly 10h 52m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 26m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
City in Monroe County, Missouri, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between St. Louis and Cameron.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Cameron.
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1
Start on Market Street
1.6 mi · 3 min · Market Street
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2
Take the ramp slight left toward I 64 West, US 40 West: Wentzville
1531 ft · 24 sec
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3
Merge slight left onto Jack Buck Memorial Highway
4.3 mi · 6 min · Jack Buck Memorial Highway
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4
Continue on Daniel Boone Expressway
5.7 mi · 7 min · Daniel Boone Expressway
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5
Continue on Avenue of the Saints
101.2 mi · 2 hr 1 min · Avenue of the Saints
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6
Take the exit slight left
76 m · 15 sec
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7
Turn left onto Paris Gravel Road
2645 ft · 1 min · Paris Gravel Road
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8
Keep slight right to continue on County Road 422
85 m · 9 sec · County Road 422
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9
Turn right onto Veterans Road
2.2 mi · 4 min · Veterans Road
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10
Take the ramp left toward US 36 West, MO 110 West: Monroe City
1226 ft · 16 sec
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11
Merge slight left onto V.F.W. Memorial Highway
5.8 mi · 7 min · V.F.W. Memorial Highway
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12
Continue on Chicago-Kansas City Expressway
149.3 mi · 2 hr 53 min · Chicago-Kansas City Expressway
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13
Take the exit slight right toward US 69, I 35 Business, US 36 Business: Cameron, Winston
1257 ft · 27 sec
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14
Keep slight left to continue on US 69, I 35 Business, US 36 Business: Cameron, Winston
34 m · 6 sec
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15
Turn left onto North Walnut Street
1.4 km · 2 min · North Walnut Street
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16
Turn right onto East 4th Street
1111 ft · 36 sec · East 4th Street
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17
Turn left onto North Cherry Street
761 ft · 35 sec · North Cherry Street
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18
Turn right onto West 2nd Street
103 m · 15 sec · West 2nd Street
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19
Arrive at your destination
0 m · 1 sec · West 2nd Street
Car Route Details
A richer read on the saved driving route between St. Louis and Cameron.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
Chicago-Kansas City Expressway
Continue on Chicago-Kansas City Expressway
149 mi · 02h 53m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving St. Louis and Sunny near Cameron.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Cameron?
The road trip is about 272.8 miles (439 km) and usually takes 05h 26m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Monroe City is a useful midpoint, sitting about 136.2 miles from St. Louis and 136.6 miles from Cameron.
How much longer is the road route than the straight-line distance?
The direct path is about 229.8 miles (369.8 km), while the road route adds roughly 43 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 6:08 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $36.31 one way or $72.63 round trip. Estimated CO2 is about 85.6 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around St. Louis and Sunny near Cameron.
Stop Ideas Near Monroe City
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Monroe City.
Quincy
La Plata
Hermann
Fort Madison station
Flight Path Map
This map shows the direct air route between St. Louis and Cameron. Straight-line distance: 229.76 mi (369.76 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Cameron
City in Missouri, USA
| Population | 8,136 |
| Coordinates | 39.7402800, -94.2410600 |
| Altitude | 315 |
| Country | United States |
End: Cameron (-94.24106, 39.74028)
Estimated Travel Time
Distance: 439 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 09h 05m |
| 40 mph (64.37 km/h) | 06h 49m |
| 50 mph (80.47 km/h) | 05h 27m |
| 60 mph (96.56 km/h) | 04h 32m |
| 70 mph (112.65 km/h) | 03h 53m |
| 80 mph (129 km/h) | 03h 24m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $36.31 | $72.63 |
| Mid-grade | $4.25 | $40.96 | $81.91 |
| Premium | $4.65 | $44.82 | $89.64 |
| Diesel | $5.30 | $51.08 | $102.16 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.