How far is St. Louis, MO from Anderson, MO?
The driving distance from St. Louis, MO to Anderson, MO is about 309.3 miles (497.7 km), with a travel time of about 05h 42m by car.
- The straight-line flight distance is about 269.4 miles (433.6 km).
- For a round trip, plan for roughly 11h 24m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 05h 42m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Chance Showers And Thunderstorms
Chance Showers And Thunderstorms
Driving Route Map
The map below follows the saved road route between St. Louis and Anderson.
Turn-by-Turn Driving Directions
Step-by-step road directions between St. Louis and Anderson.
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1
Start on Market Street
1.6 km · 2 min · Market Street
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2
Turn left onto South Jefferson Avenue
1.2 mi · 3 min · South Jefferson Avenue
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3
Take the ramp straight toward I 44 West
1051 ft · 17 sec
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4
Merge slight left onto Officer David Haynes Memorial Highway
2.3 mi · 3 min · Officer David Haynes Memorial Highway
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5
Continue on Officer Michael Barwick Memorial Highway
3.5 mi · 4 min · Officer Michael Barwick Memorial Highway
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6
Continue on Police Officer Robert Stanze Memorial Highway
2.7 mi · 3 min · Police Officer Robert Stanze Memorial Highway
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7
Continue on Police Officer Ernest M. Brockman Sr. Memorial Highway
3.5 mi · 4 min · Police Officer Ernest M. Brockman Sr. Memorial Highway
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8
Continue on Henry Shaw Ozark Corridor
264.9 mi · 4 hr 48 min · Henry Shaw Ozark Corridor
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9
Take the exit slight right toward I 49 South, US 71 South, MO 249 North: Neosho, Fort Smith
1447 ft · 25 sec
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10
Keep slight left to continue on I 49 South, US 71 South: Neosho, Fort Smith
24.1 mi · 26 min
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11
Take the exit slight right toward MO 59, US 71 Business: Goodman, Anderson
1415 ft · 31 sec
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12
Continue straight
4.7 mi · 6 min
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13
Turn right onto North State Highway 59
2841 ft · 53 sec · North State Highway 59
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14
Turn left onto Jefferson Street
567 ft · 25 sec · Jefferson Street
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15
Arrive at your destination
0 m · 1 sec · East Street
Car Route Details
A richer read on the saved driving route between St. Louis and Anderson.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Henry Shaw Ozark Corridor
Continue on Henry Shaw Ozark Corridor
265 mi · 04h 48m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Chance Showers And Thunderstorms leaving St. Louis and Chance Showers And Thunderstorms near Anderson.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from St. Louis to Anderson?
The road trip is about 309.3 miles (497.7 km) and usually takes 05h 42m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Stoutland is a useful midpoint, sitting about 154.5 miles from St. Louis and 154.8 miles from Anderson.
How much longer is the road route than the straight-line distance?
The direct path is about 269.4 miles (433.6 km), while the road route adds roughly 39.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 5:36 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.14 one way or $82.28 round trip. Estimated CO2 is about 97 kg one way.
What should you check before leaving?
Before you leave, expect Chance Showers And Thunderstorms around St. Louis and Chance Showers And Thunderstorms near Anderson.
Stop Ideas Near Stoutland
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Stoutland.
Jefferson City
Sedalia
Flight Path Map
This map shows the direct air route between St. Louis and Anderson. Straight-line distance: 269.42 mi (433.59 km).
#1 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
#2 Anderson
City in Missouri, USA
| Population | 1,915 |
| Coordinates | 36.6506300, -94.4435500 |
| Altitude | 269 |
| Country | United States |
End: Anderson (-94.44355, 36.65063)
Estimated Travel Time
Distance: 498 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 18m |
| 40 mph (64.37 km/h) | 07h 43m |
| 50 mph (80.47 km/h) | 06h 11m |
| 60 mph (96.56 km/h) | 05h 09m |
| 70 mph (112.65 km/h) | 04h 25m |
| 80 mph (129 km/h) | 03h 51m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $41.14 | $82.28 |
| Mid-grade | $4.25 | $46.40 | $92.80 |
| Premium | $4.65 | $50.78 | $101.55 |
| Diesel | $5.30 | $57.87 | $115.73 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · Apr 15, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.