How far is Anderson, MO from St. Louis, MO?
The driving distance from Anderson, MO to St. Louis, MO is about 309.3 miles (497.7 km), with a travel time of about 04h 46m by car.
- The straight-line flight distance is about 269.4 miles (433.6 km).
- For a round trip, plan for roughly 09h 33m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 46m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Anderson and St. Louis.
Turn-by-Turn Driving Directions
Step-by-step road directions between Anderson and St. Louis.
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1
Start on East Street
31 m · 5 sec · East Street
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2
Continue on East Jefferson Street
142 m · 23 sec · East Jefferson Street
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3
Turn right onto South State Highway 59
2841 ft · 53 sec · South State Highway 59
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4
At the end of the road, turn left
4.8 mi · 6 min
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5
Take the ramp left toward I 49 North, US 71 North: Joplin
1437 ft · 17 sec
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6
Merge slight left onto Corporal Bobbie J. Harper Memorial Highway
2.4 mi · 3 min · Corporal Bobbie J. Harper Memorial Highway
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7
Continue on James B. Tatum Highway
5.8 mi · 6 min · James B. Tatum Highway
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8
Continue on Special Agent Tom Crowell Memorial Highway
6 mi · 6 min · Special Agent Tom Crowell Memorial Highway
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9
Continue on Purple Heart Trail
9 mi · 10 min · Purple Heart Trail
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10
Take the exit slight right toward I 44 East, I 49 North, US 71 North: Springfield, Kansas City
3060 ft · 1 min
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11
Merge slight left onto Congressman Gene Taylor Highway
264.9 mi · 4 hr 48 min · Congressman Gene Taylor Highway
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12
Continue on Police Officer Ernest M. Brockman Sr. Memorial Highway
3.5 mi · 4 min · Police Officer Ernest M. Brockman Sr. Memorial Highway
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13
Continue on Police Officer Robert Stanze Memorial Highway
2.7 mi · 3 min · Police Officer Robert Stanze Memorial Highway
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14
Continue on Officer Michael Barwick Memorial Highway
3.5 mi · 4 min · Officer Michael Barwick Memorial Highway
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15
Continue on Officer David Haynes Memorial Highway
2.3 mi · 3 min · Officer David Haynes Memorial Highway
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16
Take the exit slight right toward Jefferson Avenue
924 ft · 22 sec
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17
Turn left onto South Jefferson Avenue
1.3 mi · 3 min · South Jefferson Avenue
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18
Turn right onto Market Street
1.6 km · 2 min · Market Street
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19
Arrive at your destination
0 m · 1 sec · Market Street
Car Route Details
A richer read on the saved driving route between Anderson and St. Louis.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Congressman Gene Taylor Highway
Merge slight left onto Congressman Gene Taylor Highway
265 mi · 04h 48m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Anderson and Sunny near St. Louis.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Anderson to St. Louis?
The road trip is about 309.3 miles (497.7 km) and usually takes 04h 46m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Stoutland is a useful midpoint, sitting about 154.3 miles from Anderson and 155 miles from St. Louis.
How much longer is the road route than the straight-line distance?
The direct path is about 269.4 miles (433.6 km), while the road route adds roughly 39.9 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:26 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.14 one way or $82.28 round trip. Estimated CO2 is about 97 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Anderson and Sunny near St. Louis.
Stop Ideas Near Stoutland
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Stoutland.
Jefferson City
Sedalia
Flight Path Map
This map shows the direct air route between Anderson and St. Louis. Straight-line distance: 269.42 mi (433.59 km).
#1 Anderson
City in Missouri, USA
| Population | 1,915 |
| Coordinates | 36.6506300, -94.4435500 |
| Altitude | 269 |
| Country | United States |
#2 St. Louis
The second most populous city in Missouri and the center of the St.
| Population | 315,685 |
| Coordinates | 38.6272700, -90.1978900 |
| Altitude | 142 |
| Country | United States |
End: Market Street (-90.197859, 38.627348)
Estimated Travel Time
Distance: 498 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 18m |
| 40 mph (64.37 km/h) | 07h 43m |
| 50 mph (80.47 km/h) | 06h 11m |
| 60 mph (96.56 km/h) | 05h 09m |
| 70 mph (112.65 km/h) | 04h 25m |
| 80 mph (129 km/h) | 03h 51m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $41.14 | $82.28 |
| Mid-grade | $4.25 | $46.40 | $92.80 |
| Premium | $4.65 | $50.78 | $101.55 |
| Diesel | $5.30 | $57.87 | $115.73 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.