How far is Anderson, MO from Saint Charles, MO?
The driving distance from Anderson, MO to Saint Charles, MO is about 312.9 miles (503.5 km), with a travel time of about 04h 50m by car.
- The straight-line flight distance is about 261.9 miles (421.5 km).
- For a round trip, plan for roughly 09h 40m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM CDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 04h 50m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Missouri, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Anderson and Saint Charles.
Turn-by-Turn Driving Directions
Step-by-step road directions between Anderson and Saint Charles.
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1
Start on East Street
31 m · 5 sec · East Street
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2
Continue on East Jefferson Street
142 m · 23 sec · East Jefferson Street
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3
Turn right onto South State Highway 59
2841 ft · 53 sec · South State Highway 59
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4
At the end of the road, turn left
4.8 mi · 6 min
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5
Take the ramp left toward I 49 North, US 71 North: Joplin
1437 ft · 17 sec
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6
Merge slight left onto Corporal Bobbie J. Harper Memorial Highway
2.4 mi · 3 min · Corporal Bobbie J. Harper Memorial Highway
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7
Continue on James B. Tatum Highway
5.8 mi · 6 min · James B. Tatum Highway
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8
Continue on Special Agent Tom Crowell Memorial Highway
6 mi · 6 min · Special Agent Tom Crowell Memorial Highway
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9
Continue on Purple Heart Trail
9 mi · 10 min · Purple Heart Trail
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10
Take the exit slight right toward I 44 East, I 49 North, US 71 North: Springfield, Kansas City
3060 ft · 1 min
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11
Merge slight left onto Congressman Gene Taylor Highway
263.7 mi · 4 hr 46 min · Congressman Gene Taylor Highway
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12
Take the exit slight right toward I 270: Chicago, Memphis
871 ft · 19 sec
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13
Keep slight left to continue on I 270 North: Chicago
551 ft · 12 sec
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14
Continue on I 270 North: Chicago
2638 ft · 53 sec
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15
Merge slight left
12.6 mi · 16 min
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16
Take the exit slight right toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport
1 mi · 1 min
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17
Keep slight left to continue on I 70 West: Kansas City
645 ft · 11 sec
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18
Continue on I 70 West: Kansas City
1 km · 57 sec
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19
Merge slight left
2.7 mi · 3 min
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20
Take the exit slight right toward I 70 Business: Fifth Street
841 ft · 18 sec
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21
Keep slight right to continue on I 70 Business: Fifth Street North, Bass Pro Drive, Ameristar Boulevard
71 m · 5 sec
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22
Turn slight right onto South Fifth Street
1.6 km · 2 min · South Fifth Street
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23
Turn right onto Jefferson Street
1093 ft · 44 sec · Jefferson Street
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24
Turn left onto North Second Street
949 ft · 34 sec · North Second Street
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25
Arrive at your destination
0 m · 1 sec · North Second Street
Car Route Details
A richer read on the saved driving route between Anderson and Saint Charles.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Congressman Gene Taylor Highway
Merge slight left onto Congressman Gene Taylor Highway
264 mi · 04h 46m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Anderson and Sunny near Saint Charles.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Anderson to Saint Charles?
The road trip is about 312.9 miles (503.5 km) and usually takes 04h 50m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Stoutland is a useful midpoint, sitting about 156.2 miles from Anderson and 156.7 miles from Saint Charles.
How much longer is the road route than the straight-line distance?
The direct path is about 261.9 miles (421.5 km), while the road route adds roughly 51 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM CDT. If you want a more comfortable same-day return, try to leave by 7:20 AM CDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $41.63 one way or $83.26 round trip. Estimated CO2 is about 98.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Anderson and Sunny near Saint Charles.
Stop Ideas Near Stoutland
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Stoutland.
Jefferson City
Sedalia
Flight Path Map
This map shows the direct air route between Anderson and Saint Charles. Straight-line distance: 261.92 mi (421.52 km).
#1 Anderson
City in Missouri, USA
| Population | 1,915 |
| Coordinates | 36.6506300, -94.4435500 |
| Altitude | 269 |
| Country | United States |
#2 Saint Charles
A city in St.
| Population | 71,761 |
| Coordinates | 38.7839400, -90.4812300 |
| Altitude | 147 |
| Country | United States |
End: North Second Street (-90.481269, 38.783952)
Estimated Travel Time
Distance: 504 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 10h 25m |
| 40 mph (64.37 km/h) | 07h 49m |
| 50 mph (80.47 km/h) | 06h 15m |
| 60 mph (96.56 km/h) | 05h 12m |
| 70 mph (112.65 km/h) | 04h 28m |
| 80 mph (129 km/h) | 03h 54m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.77 | $41.63 | $83.26 |
| Mid-grade | $4.25 | $46.95 | $93.91 |
| Premium | $4.65 | $51.38 | $102.76 |
| Diesel | $5.30 | $58.56 | $117.11 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Missouri · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.