How far is Seneca, SC from Florence, SC?
The driving distance from Seneca, SC to Florence, SC is about 217 miles (349.3 km), with a travel time of about 03h 24m by car.
- The straight-line flight distance is about 184.9 miles (297.6 km).
- For a round trip, plan for roughly 06h 49m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 8:00 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 03h 24m.
An early departure helps you fit a real stop into the day without turning the return into a late-night drive.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Human settlement in Newberry County, South Carolina, United States of America
Route Weather Snapshot
Check the forecast at both ends before you head out.
Sunny
Driving Route Map
The map below follows the saved road route between Seneca and Florence.
Turn-by-Turn Driving Directions
Step-by-step road directions between Seneca and Florence.
-
1
Start on North Townville Street
7 m · 5 sec · North Townville Street
-
2
Turn right onto East North 1st Street
1.4 mi · 4 min · East North 1st Street
-
3
Turn right
27.3 mi · 38 min
-
4
Take the exit slight right
1547 ft · 42 sec
-
5
Keep slight right
763 ft · 21 sec
-
6
Merge slight left onto Highway 153
6.3 mi · 10 min · Highway 153
-
7
Take the exit right
1932 ft · 47 sec
-
8
Merge slight left onto Southern Connector
10.9 mi · 12 min · Southern Connector
-
9
Take the exit slight right toward I 385 South: Columbia
3014 ft · 1 min
-
10
Merge slight right
1140 ft · 14 sec
-
11
Merge slight left onto Golden Strip Freeway
29.8 mi · 32 min · Golden Strip Freeway
-
12
Merge slight left
55.2 mi · 1 hr
-
13
Take the exit slight right toward I 20 East: Florence
1687 ft · 41 sec
-
14
Merge slight left
79.3 mi · 1 hr 30 min
-
15
Turn left onto West Evans Street
2.4 mi · 5 min · West Evans Street
-
16
Turn right onto Warley Street
644 ft · 20 sec · Warley Street
-
17
Turn left onto West Cheves Street
1.1 km · 1 min · West Cheves Street
-
18
Turn right
40 m · 12 sec
-
19
Turn right
15 m · 4 sec
-
20
Arrive at your destination
0 m · 1 sec
Car Route Details
A richer read on the saved driving route between Seneca and Florence.
Highway-focused drive
Most of the mileage stays on named highways, so the important moments are ramps, exits, merges, and the final local approach.
I 20 East
Merge slight left
79.3 mi · 01h 30m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
A longer out-and-back drive
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
Sunny leaving Seneca and Sunny near Florence.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Seneca to Florence?
The road trip is about 217 miles (349.3 km) and usually takes 03h 24m in normal driving conditions.
Is this a same-day trip or an overnight route?
This is still possible in one day, but it becomes a long driving day. Leaving early and planning your stop window matters more here.
What is the halfway point on this route?
Pomaria is a useful midpoint, sitting about 107.5 miles from Seneca and 109.5 miles from Florence.
How much longer is the road route than the straight-line distance?
The direct path is about 184.9 miles (297.6 km), while the road route adds roughly 32.1 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 8:00 AM EDT. If you want a more comfortable same-day return, try to leave by 10:10 AM EDT.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $30.34 one way or $60.68 round trip. Estimated CO2 is about 68.1 kg one way.
What should you check before leaving?
Before you leave, expect Sunny around Seneca and Sunny near Florence.
Stop Ideas Near Pomaria
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Pomaria.
Columbia
Camden
Spartanburg
Denmark
Flight Path Map
This map shows the direct air route between Seneca and Florence. Straight-line distance: 184.93 mi (297.61 km).
#1 Seneca
City in South Carolina
| Population | 8,564 |
| Coordinates | 34.6856600, -82.9532000 |
| Altitude | 294 |
| Country | United States |
#2 Florence
Civil town in Florence County, Wisconsin
| Population | 38,467 |
| Coordinates | 34.1954300, -79.7625600 |
| Altitude | 42 |
| Country | United States |
End: (-79.762378, 34.19544)
Estimated Travel Time
Distance: 349 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 07h 13m |
| 40 mph (64.37 km/h) | 05h 25m |
| 50 mph (80.47 km/h) | 04h 20m |
| 60 mph (96.56 km/h) | 03h 37m |
| 70 mph (112.65 km/h) | 03h 06m |
| 80 mph (129 km/h) | 02h 42m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $3.96 | $30.34 | $60.68 |
| Mid-grade | $4.43 | $33.93 | $67.85 |
| Premium | $4.78 | $36.60 | $73.20 |
| Diesel | $5.62 | $43.08 | $86.16 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in South Carolina · Apr 23, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.