How far is Port Saint Lucie, FL from Gretna, FL?
The driving distance from Port Saint Lucie, FL to Gretna, FL is about 400 miles (643.8 km), with a travel time of about 07h 18m by car.
- The straight-line flight distance is about 347.2 miles (558.8 km).
- For a round trip, plan for roughly 14h 36m of driving time before adding stops, traffic, or weather delays.
- A comfortable departure window is usually 6:00 AM to 7:30 AM EDT.
Reverse, save, or send this route
This drive is better planned with a longer stop or an overnight stay. Copy the route link, send it to another device, or print a clean version before you head out.
This drive is better planned with a longer stop or an overnight stay.
Flight Distance
Driving Distance
Gas Cost Calculator
Leave and Arrive Planner
Pick a departure time to see your estimated arrival and same-day return window.
Drive time stays fixed at 07h 18m.
Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
You are leaving earlier than the recommended window, which gives you extra margin for breaks and traffic.
Halfway Point
A useful midpoint for breaks, coffee, or meeting in the middle.
Town in Marion County, Florida, United States
Route Weather Snapshot
Check the forecast at both ends before you head out.
Mostly Cloudy then Chance Showers And Thunderstorms
Rain Showers Likely
Driving Route Map
The map below follows the saved road route between Port Saint Lucie and Gretna.
Turn-by-Turn Driving Directions
Step-by-step road directions between Port Saint Lucie and Gretna.
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1
Start on Southwest Carter Avenue
66 m · 11 sec · Southwest Carter Avenue
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2
Turn right onto Southeast Airoso Boulevard
1.6 mi · 3 min · Southeast Airoso Boulevard
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3
Turn right onto Southwest Port Saint Lucie Boulevard
1.3 km · 1 min · Southwest Port Saint Lucie Boulevard
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4
Turn left onto Southwest Bayshore Boulevard
560 ft · 22 sec · Southwest Bayshore Boulevard
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5
Take the ramp straight toward Florida's Turnpike Toll
2787 ft · 1 min
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6
Keep slight right to continue on Orlando, Florida's Turnpike North
1842 ft · 45 sec
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7
Merge slight left onto Florida's Turnpike
164.8 mi · 2 hr 57 min · Florida's Turnpike
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8
Keep slight left to continue on Florida's Turnpike
1281 ft · 16 sec · Florida's Turnpike
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9
Merge slight left
106.9 mi · 1 hr 55 min
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10
Take the exit slight right toward I 10: Jacksonville, Tallahassee
820 ft · 16 sec
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11
Keep slight left to continue on I 10 West: Tallahassee
1569 ft · 30 sec
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12
Merge slight right
115 mi · 2 hr 3 min
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13
Take the exit slight right toward FL 267: Quincy
1571 ft · 38 sec
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14
Turn right
3.4 mi · 6 min
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15
Turn left onto West Jefferson Street
1.2 mi · 2 min · West Jefferson Street
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16
Continue on Blue Star Highway
3.1 mi · 4 min · Blue Star Highway
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17
Continue on Main Street
1 mi · 2 min · Main Street
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18
Turn right onto Broad Avenue
800 ft · 37 sec · Broad Avenue
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19
Turn right onto 2nd Street
15 m · 4 sec · 2nd Street
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20
Arrive at your destination
0 m · 1 sec · 2nd Street
Car Route Details
A richer read on the saved driving route between Port Saint Lucie and Gretna.
Long-distance drive
This route is long enough that fuel, rest stops, weather, and timing matter more than any single maneuver.
Florida's Turnpike
Merge slight left onto Florida's Turnpike
165 mi · 02h 57m
Route Summary
A quick read on whether this route feels easy, ambitious, or worth planning around.
Better with a longer stop
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
Mostly Cloudy then Chance Showers And Thunderstorms leaving Port Saint Lucie and Rain Showers Likely near Gretna.
Trip Questions
Direct answers travelers usually want before committing to the drive.
How long does it take to drive from Port Saint Lucie to Gretna?
The road trip is about 400 miles (643.8 km) and usually takes 07h 18m in normal driving conditions.
Is this a same-day trip or an overnight route?
This route is long enough that most travelers will be better off planning an overnight stay or a more deliberate stop window.
What is the halfway point on this route?
Reddick is a useful midpoint, sitting about 200.1 miles from Port Saint Lucie and 199.9 miles from Gretna.
How much longer is the road route than the straight-line distance?
The direct path is about 347.2 miles (558.8 km), while the road route adds roughly 52.8 extra miles because roads do not follow the straight air line.
When is the best time to leave for this route?
A good departure window is usually 6:00 AM to 7:30 AM EDT. Starting early still helps, but most travelers will want a longer stop or an overnight stay on a route this long.
How much will gas cost for this route?
Using about 28.3 MPG, regular gas is estimated at $58.57 one way or $117.14 round trip. Estimated CO2 is about 125.5 kg one way.
What should you check before leaving?
Before you leave, expect Mostly Cloudy then Chance Showers And Thunderstorms around Port Saint Lucie and Rain Showers Likely near Gretna.
Stop Ideas Near Reddick
Useful break, food, and waypoint ideas within about 15 miles of the route midpoint.
Transit and Meeting Points
Useful pickup, handoff, or rendezvous points close to Reddick.
Ocala, Florida
Gainesville, Florida
Waldo, Florida
The Villages-Lady Lake, FL
Flight Path Map
This map shows the direct air route between Port Saint Lucie and Gretna. Straight-line distance: 347.22 mi (558.79 km).
#1 Port Saint Lucie
The second most populous city in St.
| Population | 209,715 |
| Coordinates | 27.2939300, -80.3503300 |
| Altitude | 5 |
| Country | United States |
#2 Gretna
Human settlement in Gadsden County, Florida, United States of America
| Population | 1,430 |
| Coordinates | 30.6171400, -84.6599100 |
| Altitude | 90 |
| Country | United States |
End: Gretna (-84.65991, 30.61714)
Estimated Travel Time
Distance: 644 km by road
| Speed | Time |
|---|---|
| 30 mph (48.3 km/h) | 13h 19m |
| 40 mph (64.37 km/h) | 10h 00m |
| 50 mph (80.47 km/h) | 08h 00m |
| 60 mph (96.56 km/h) | 06h 40m |
| 70 mph (112.65 km/h) | 05h 42m |
| 80 mph (129 km/h) | 04h 59m |
Fuel, Round Trip and CO2
Estimated fuel cost and emissions for this route.
| Fuel | $/gal | One way | Round trip |
|---|---|---|---|
| Regular gas | $4.15 | $58.57 | $117.14 |
| Mid-grade | $4.60 | $64.90 | $129.79 |
| Premium | $4.90 | $69.13 | $138.26 |
| Diesel | $4.35 | $61.42 | $122.84 |
Assumes 8.3 L/100 km (about 28.3 MPG). CO2 is an estimate and varies by vehicle, fuel blend, traffic, and terrain.
Prices in Florida · May 13, 2026
Distance to Other Cities
Planning a road trip? See the full trip guide on Trip.ovh — stops, fuel costs, weather, and departure timing.